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Amgen vs Moderna: revenue, profit, margins and growth compared

Amgen brought in $36.8B of revenue in fiscal 2025, Moderna $1.9B in fiscal 2025. Revenue changed by +10.0% at Amgen and -39.9% at Moderna on the year before, so Amgen grew faster. Amgen kept 21.0% of its revenue as net profit, Moderna -145.2%. Free cash flow was $8.1B at Amgen and -$2.1B at Moderna.

Side by side, latest fiscal year

AMGNMRNA
Fiscal year endedFY2025 (December 31, 2025)FY2025 (December 31, 2025)
Revenue$36.8B$1.9B
Revenue growth+10.0%-39.9%
Net income$7.7B-$2.8B
Net margin21.0%-145.2%
Free cash flow$8.1B-$2.1B
Free cash flow margin22.0%-106.2%
Earnings per share (diluted)$14.23-$7.26
Cash$9.1B$2.6B
Debt$54.6B$590M
Price to earnings29.1n/a
Market value$224.2B$79.4B
Dividend yield2.33%n/a
Rank by revenue in sector#20 of 523 · Health care#111 of 523 · Health care

Over the years

Revenue
AMGN FY2018: $23.7BAMGN FY2019: $23.4BAMGN FY2020: $25.4BAMGN FY2021: $26BAMGN FY2022: $26.3BAMGN FY2023: $28.2BAMGN FY2024: $33.4BAMGN FY2025: $36.8BMRNA FY2018: $135.1MMRNA FY2019: $60.2MMRNA FY2020: $803MMRNA FY2021: $18.5BMRNA FY2022: $19.3BMRNA FY2023: $6.8BMRNA FY2024: $3.2BMRNA FY2025: $1.9BFY18FY19FY20FY21FY22FY23FY24FY25
AMGN $36.8BMRNA $1.9B
Net income
AMGN FY2018: $8.4BAMGN FY2019: $7.8BAMGN FY2020: $7.3BAMGN FY2021: $5.9BAMGN FY2022: $6.6BAMGN FY2023: $6.7BAMGN FY2024: $4.1BAMGN FY2025: $7.7BMRNA FY2018: -$384.7MMRNA FY2019: -$514MMRNA FY2020: -$747MMRNA FY2021: $12.2BMRNA FY2022: $8.4BMRNA FY2023: -$4.7BMRNA FY2024: -$3.6BMRNA FY2025: -$2.8BFY18FY19FY20FY21FY22FY23FY24FY25
AMGN $7.7BMRNA -$2.8B
Net margin
AMGN FY2018: 35.3%AMGN FY2019: 33.6%AMGN FY2020: 28.6%AMGN FY2021: 22.7%AMGN FY2022: 24.9%AMGN FY2023: 23.8%AMGN FY2024: 12.2%AMGN FY2025: 21.0%MRNA FY2018: -284.8%MRNA FY2019: -853.7%MRNA FY2020: -93.0%MRNA FY2021: 66.1%MRNA FY2022: 43.4%MRNA FY2023: -68.8%MRNA FY2024: -110.0%MRNA FY2025: -145.2%FY18FY19FY20FY21FY22FY23FY24FY25
AMGN 21.0%MRNA -145.2%
Revenue growth
AMGN FY2019: -1.6%AMGN FY2020: +8.8%AMGN FY2021: +2.2%AMGN FY2022: +1.3%AMGN FY2023: +7.1%AMGN FY2024: +18.6%AMGN FY2025: +10.0%MRNA FY2019: -55.4%MRNA FY2020: +1,233.7%MRNA FY2021: +2,200.2%MRNA FY2022: +4.3%MRNA FY2023: -64.4%MRNA FY2024: -52.7%MRNA FY2025: -39.9%FY19FY20FY21FY22FY23FY24FY25
AMGN +10.0%MRNA -39.9%
Free cash flow
AMGN FY2018: $10.6BAMGN FY2019: $8.5BAMGN FY2020: $9.9BAMGN FY2021: $8.4BAMGN FY2022: $8.8BAMGN FY2023: $7.4BAMGN FY2024: $10.4BAMGN FY2025: $8.1BMRNA FY2018: -$436.6MMRNA FY2019: -$491MMRNA FY2020: $2BMRNA FY2021: $13.3BMRNA FY2022: $4.6BMRNA FY2023: -$3.8BMRNA FY2024: -$4.1BMRNA FY2025: -$2.1BFY18FY19FY20FY21FY22FY23FY24FY25
AMGN $8.1BMRNA -$2.1B

Fiscal years as each company reports them; the two may end in different months.

Questions about Amgen and Moderna

Which is bigger by revenue, Amgen or Moderna?

Amgen is bigger by revenue: $36.8B in fiscal 2025, against $1.9B for Moderna in fiscal 2025.

Which keeps more of its revenue as profit, Amgen or Moderna?

Amgen had a net margin of 21.0% in fiscal 2025; Moderna had -145.2% in fiscal 2025.

Which grew revenue faster, Amgen or Moderna?

In their latest fiscal years revenue changed by +10.0% at Amgen and -39.9% at Moderna.

Where do these numbers come from?

From the annual reports each company files with the SEC (10-K, or 20-F and 40-F for foreign companies), read from their XBRL data. Margins and growth are simple arithmetic on those figures. Nothing here is a recommendation.

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