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Financial statements

Syndax Pharmaceuticals Inc financial statements

Income statement, balance sheet and cash flow statement for the last 10 fiscal years, taken from the XBRL data Syndax Pharmaceuticals Inc files with the SEC in its annual reports.

In USD millions, except per-share amounts. Outflows in the cash flow statement are negative.

Income statement

FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue1.222.111.521.521.521400023.7172
Research and development31.748.260.14350.488.2118163242259
Selling, general and administrative25.233.366.9121180
General and administrative13.315.917.316.122.525.233.3
Operating expenses4564.177.459.172.9113152230363445
Operating income-43.8-62-75.9-57.5-71.426.2-152-230-340-273
Interest expense2.361.93.140.21-00.01
Interest income1.941.570.840.45.8721.226.122.7
Other non-operating income-0.711.151.921.49-1.74-1.292.4220.620.9-12.3
Income tax0000000.43
Net income-44.5-60.8-74-56-73.224.9-149-209-319-285
EBITDA-43.7-61.9-75.8-57.4-71.369.2-119-218-332-267
EPS, basic-3.22-2.90-2.92-1.84-1.870.48-2.46-2.98-3.72-3.29
EPS, diluted-3.22-2.90-2.92-1.84-1.870.46-2.46-2.98-3.72-3.29
Shares, basic (weighted)14.62125.430.541.352.160.870.485.686.6
Shares, diluted (weighted)14.62125.430.541.353.660.870.485.686.6

Balance sheet

FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash and equivalents23.835.233.824.611522274.4295154135
Short-term investments81.594.847.135.2178218401275419259
Receivables07.638
Inventory00.3732.8
Other current assets3.033.362.332.565.681.451.9208.5413.5
Total current assets10913383.362.3299448490581603528
Property, plant and equipment0.260.270.370.280.190.280.020.0100.18
Lease right-of-use assets0.720.290.981.041.492.021.34
Long-term investments3.2505.4729.81200
Other non-current assets0.240.230.220.21.2700.810.460
Total assets10913783.963.5301450497613725530
Accounts payable2.382.231.446.183.515.674.359.9611.616.6
Accrued liabilities1.642.392.82.83.214.345.9511.214.524.4
Deferred revenue1.221.571.521.521.52
Short-term debt0344344
Total current liabilities10.415.816.118.418.920.729.158.1104120
Long-term debt0332
Lease liabilities0.420.10.710.710.581.58
Other non-current liabilities0.290.310.140.010
Total liabilities24.932.930.931.948.441.329.858.7437465
Total debt0338350
Paid-in capital3894714925278219521,1611,4561,5091,571
Retained earnings-305-366-439-495-569-544-693-902-1,221-1,507
Shareholders' equity84.11045331.625240846755428864.6
Total equity84.11045331.625240846755428864.6
Total liabilities and equity10913783.963.5301450497613725530
Shares outstanding18.224.424.827.147.95568.184.885.787.4

Cash flow statement

FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Net income-44.5-60.8-74-56-73.224.9-149-209-319-285
Depreciation and amortization0.090.080.080.090.0943331286
Stock-based compensation4.715.456.26.019.0613.316314347.5
Change in receivables00-7.6-30.4
Change in inventory00-0.37-32.1
Change in payables0.92-0.19-0.794.74-2.672.16-1.325.611.674.95
Cash from operations-35.2-47.4-68.5-50.6-71.329.1-134-161-275-323
Capital expenditures-0.26-0.08-0.190-0.13000-0.19
Purchases of investments-158-152-78.8-104-279-295-495-355-557-196
Cash from investing-18.3-17.151.412.8-143-40.9-186118-220290
Stock issued2.060.280.030.186.636.3411.55.13812.1
Cash from financing54.275.715.728.630411817226435313.7
Net change in cash0.7611.3-1.4-9.2690.6107-148221-141-19.3
Free cash flow-35.4-47.5-68.7-71.329-134-161-275-323
Interest paid01.6322.0600
Income taxes paid0

Key metrics

Worked out from the statements above. Latest values use the trailing twelve months to June 30, 2026; growth uses fiscal years. Valuation uses the share price of $18.20 on September 25, 2026.

Profitability

MetricValueHow it is calculated
Operating margin-77.1%Operating income / revenue.
Net margin-87.6%Net income / revenue.
Operating cash flow margin-87.6%Cash from operations / revenue.
Return on equity (ROE)-1,462.0%Net income / average shareholders' equity (opening and closing). Not shown when equity is negative.
Return on assets (ROA)-31.4%Net income / average total assets.
Return on invested capital (ROIC)-535.9%Approximation: operating income x (1 - tax rate) / average (total debt + equity - cash). Tax rate is the effective rate when between 0% and 50%, else 21%.
R&D / revenue103.9%Research and development expense / revenue.
Stock-based pay / revenue19.6%Stock-based compensation (from the cash flow statement) / revenue.

Growth

MetricValueHow it is calculated
Revenue growth, 1y627.8%Revenue vs the same period a year earlier. Only from a positive base.
Revenue CAGR, 5y157.7%Compound annual growth of revenue over 5 fiscal years: (end / start)^(1/5) - 1. Only when both values are positive.
Book value growth, 1y-77.6%Book value vs the same period a year earlier. Only from a positive base.
Book value CAGR, 3y-48.3%Compound annual growth of book value over 3 fiscal years: (end / start)^(1/3) - 1. Only when both values are positive.
Book value CAGR, 5y-23.8%Compound annual growth of book value over 5 fiscal years: (end / start)^(1/5) - 1. Only when both values are positive.
Total assets growth, 1y-26.9%Total assets vs the same period a year earlier. Only from a positive base.
Total assets CAGR, 3y2.1%Compound annual growth of total assets over 3 fiscal years: (end / start)^(1/3) - 1. Only when both values are positive.
Total assets CAGR, 5y12.0%Compound annual growth of total assets over 5 fiscal years: (end / start)^(1/5) - 1. Only when both values are positive.
Share count change, 1y1.2%Change in diluted weighted shares vs a year earlier. Negative means buybacks shrank the share count; positive means dilution.
Share count change per year, 3y12.5%Change in diluted weighted shares, per year over 3 years. Negative means buybacks shrank the share count; positive means dilution.
Share count change per year, 5y16.0%Change in diluted weighted shares, per year over 5 years. Negative means buybacks shrank the share count; positive means dilution.

Balance sheet health

MetricValueHow it is calculated
Current ratio6.77xCurrent assets / current liabilities.
Quick ratio5.50x(Cash + short-term investments + receivables) / current liabilities.
Cash ratio5.50x(Cash + short-term investments) / current liabilities.
Debt / equity23.2xTotal debt / shareholders' equity. Not shown when equity is negative.
Debt / assets49.7%Total debt / total assets.
Liabilities / assets97.9%Total liabilities / total assets.
Net debt-$197.9MTotal debt - cash - short-term investments. Negative means more cash than debt.
Interest coverage-97,085xOperating income / interest expense.
Working capital$575.4MCurrent assets - current liabilities.
Tangible book value$15.1MShareholders' equity - goodwill - intangible assets.

Efficiency

MetricValueHow it is calculated
Asset turnover0.36xRevenue / average total assets.
Fixed asset turnover1,189xRevenue / average property, plant and equipment.

Per share

MetricValueHow it is calculated
EPS, diluted-$2.48Net income per diluted share, as reported (split-adjusted). Over the last twelve months: the four quarters summed, or net income / latest diluted shares when a quarter has no reported EPS.
Revenue per share$2.83Revenue / diluted weighted shares.
Operating cash flow per share-$2.48Cash from operations / diluted weighted shares.
Book value per share$0.17Shareholders' equity / shares outstanding (diluted weighted shares when not reported).
Tangible book per share$0.17Tangible book value / shares outstanding.
Cash per share$6.15(Cash + short-term investments) / shares outstanding.

Valuation

MetricValueHow it is calculated
Market cap$1.63BShare price x shares outstanding.
Enterprise value$1.43BMarket cap + total debt - cash - short-term investments.
P/S6.45xMarket cap / revenue.
P/B108xMarket cap / shareholders' equity. Only when equity is positive.
Price / tangible book108xMarket cap / tangible book value, when positive.
EV/Sales5.66xEnterprise value / revenue.
Earnings yield-13.6%Net income / market cap (the inverse of P/E).
What was Syndax Pharmaceuticals Inc's revenue in fiscal 2025?

Syndax Pharmaceuticals Inc reported revenue of $172.4M for fiscal 2025, 627.8% higher than the year before.

Was Syndax Pharmaceuticals Inc profitable in fiscal 2025?

No. It reported a net loss of $285.4M.

How much free cash flow did Syndax Pharmaceuticals Inc generate in fiscal 2025?

Cash from operations of $323.0M minus capital expenditures of $187.0K left free cash flow of -$323.2M.

Source: SEC EDGAR XBRL company facts. Where a company tags only year-to-date figures, quarters are worked out as differences. Where a line is not tagged it is left empty, never estimated.

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