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Syndax Pharmaceuticals Inc (SNDX)

Syndax Pharmaceuticals Inc brought in $289.4M of revenue over the twelve months to September 30, 2026, up 159.5% from a year earlier. It posted a net loss of $209.5M. In fiscal 2025 capital spending exceeded operating cash flow by $323.2M. At September 30, 2026 it held $135.9M in cash against $350M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 2, 2026.

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Price
$9.69
+1.47% on the day · November 10, 2026
52-week range $9.15 to $25.59
Market cap
$865.3M
Revenue (last 12 months)
$289.4M
+159.5% year on year
Net margin
-72.4%

Key facts about Syndax Pharmaceuticals Inc

Net worth
Syndax Pharmaceuticals Inc has a market value (market cap) of $865.3M at the latest share price, and shareholders' equity of -$17.2M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $172.4M (+627.8% year on year), with a net loss of $285.4M. Over the 12 months to September 30, 2026: revenue $289.4M, net loss $209.5M.
Cash flow
In fiscal 2025 operations used $323M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 2, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Syndax Pharmaceuticals Inc's next report is expected around January 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Syndax Pharmaceuticals Inc does

Syndax Pharmaceuticals Inc is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker SNDX.

Revenue and profit by year

Revenue
FY18: $1.5M $1.5M FY18FY19: $1.5M $1.5M FY19FY20: $1.5M $1.5M FY20FY21: $139.7M $139.7M FY21FY22: $0 $0 FY22FY23: $0 $0 FY23FY24: $23.7M $23.7M FY24FY25: $172.4M $172.4M FY25
Net income
FY18: -$74M -$74M FY18FY19: -$56M -$56M FY19FY20: -$73.2M -$73.2M FY20FY21: $24.9M $24.9M FY21FY22: -$149.3M -$149.3M FY22FY23: -$209.4M -$209.4M FY23FY24: -$318.8M -$318.8M FY24FY25: -$285.4M -$285.4M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$172.4M-$273.1M-$285.4M-$3.29-$323.2M
2024$23.7M-$339.7M-$318.8M-$3.72-$274.9M
2023$0-$230M-$209.4M-$2.98-$160.6M
2022$0-$151.8M-$149.3M-$2.46-$133.7M
2021$139.7M$26.2M$24.9M$0.46$29M
2020$1.5M-$71.4M-$73.2M-$1.87-$71.3M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around January 11, 2027.

Estimated from its filing rhythm: 52 weeks after its report of January 12, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where SNDX ranks in Health care

Revenue$172.4M
#288 of 751 in Health care · Top 38%
Revenue growth+627.8%
#15 of 532 in Health care · Top 3%
Net margin-165.6%
#471 of 544 in Health care · Bottom 13%
Free cash flow margin-187.5%
#434 of 490 in Health care · Bottom 11%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Syndax Pharmaceuticals Inc has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 2, 2026
    Quarterly report 10-Q · period to September 30, 2026Revenue rose 82% to $83.3M versus the same quarter last year; diluted EPS -$0.55 versus -$0.70.
  2. November 2, 2026
  3. August 7, 2026
  4. August 4, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue rose 92% to $72.8M versus the same quarter last year; diluted EPS -$0.55 versus -$0.83.
  5. August 4, 2026
  6. July 14, 2026
  7. June 10, 2026
  8. June 10, 2026
  9. June 4, 2026
  10. June 4, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 30, 2026. Insider transactions on SEC

Insider trades

What the people running Syndax Pharmaceuticals Inc did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $113.7K worth of shares in the last 90 days and bought none on the open market. All of the selling was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$113.7K
last 90 days
Net sold
8,000
$113.7K
DateInsiderWhatSharesPriceValueFiling
October 29, 2026 Podlesak DennisDirector Exercised options 8,000 $11.81 $94.5K Form 4
October 29, 2026 Podlesak DennisDirector Soldpre-planned (10b5-1) 8,000 $14.21 $113.7K Form 4
July 8, 2026 Metzger Michael AChief Executive Officer, Director Exercised options 32,375 $6.38 $206.6K Form 4
July 8, 2026 Metzger Michael AChief Executive Officer, Director Soldpre-planned (10b5-1) 32,375 $24.24 $784.8K Form 4
June 12, 2026 Botwood Nicholas A.J.Head of R&D, CMO Exercised options 31,235 $13.82 $431.7K Form 4
June 12, 2026 Botwood Nicholas A.J.Head of R&D, CMO Soldpre-planned (10b5-1) 31,235 $18.14 $566.6K Form 4
June 11, 2026 Botwood Nicholas A.J.Head of R&D, CMO Exercised options 22,515 $13.82 $311.2K Form 4
June 11, 2026 Botwood Nicholas A.J.Head of R&D, CMO Soldpre-planned (10b5-1) 34,280 $18.00 $617K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns SNDX

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Kynam Capital Management, LP13G, passive with 2 related filers 9.98% 8,520,000 February 14, 2025
Vanguard Capital Management13G, passive 5.05% 4,457,143 April 30, 2026

Latest filings below 5%: Point72 Asset Management, L.P. 2.3% (May 15, 2026); The Vanguard Group 0% (March 27, 2026); Wellington Management Group LLP 0% (March 7, 2025).

Largest institutional holders

No Form 13F positions imported for this company yet.

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

9 insiders reported holding 1,428,743 shares in total, about $13.8M at the last price.

HolderSharesAs of
Metzger Michael AChief Executive Officer, Director 484,843 July 8, 2026
Podlesak DennisDirector 239,763 October 29, 2026
Goldan Keith A.Chief Financial Officer 139,252 June 1, 2026
Katkin KeithDirector 124,000 February 4, 2026
Jarrett JenniferDirector 114,000 February 4, 2026
Legault PierreDirector 114,000 February 4, 2026
Huber Martin H. Jr.Director 103,000 February 4, 2026
Botwood Nicholas A.J.Head of R&D, CMO 60,885 June 12, 2026
Rizo AleksandraDirector 49,000 February 4, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about SNDX

What does Syndax Pharmaceuticals Inc do?

Syndax Pharmaceuticals Inc is a company in the Health care sector, listed on NASDAQ as SNDX. Its shares trade on NASDAQ under the ticker SNDX.

What is Syndax Pharmaceuticals Inc's net worth?

Syndax Pharmaceuticals Inc has a market value (market cap) of $865.3M at the latest share price, and shareholders' equity of -$17.2M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Syndax Pharmaceuticals Inc profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $209.5M on revenue of $289.4M.

How much revenue does Syndax Pharmaceuticals Inc make?

Over the twelve months to September 30, 2026 Syndax Pharmaceuticals Inc reported revenue of $289.4M. That is 159.5% more than a year earlier.

When did Syndax Pharmaceuticals Inc last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 2, 2026. It covers the period to September 30, 2026.

When is Syndax Pharmaceuticals Inc's next earnings report?

Syndax Pharmaceuticals Inc's next report is expected around January 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Syndax Pharmaceuticals Inc tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.