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Caris Life Sciences, Inc. (CAI)

Caris Life Sciences, Inc. brought in $1B of revenue over the twelve months to September 30, 2026. Net income was $96.1M, a net margin of 9.2%. Operating cash flow minus capital spending left $66.9M of free cash flow in fiscal 2025. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 4, 2026.

Free, no password. An email when CAI files with the SEC.

Price
$24.43
-4.46% on the day · November 10, 2026
52-week range $14.19 to $36.50
Market cap
$6.9B
Revenue (last 12 months)
$1B
Net margin
9.2%

Key facts about Caris Life Sciences, Inc.

Net worth
Caris Life Sciences, Inc. has a market value (market cap) of $6.9B at the latest share price, and shareholders' equity of $639.5M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $812M (+97.0% year on year), with a net loss of $68.1M. Over the 12 months to September 30, 2026: revenue $1B, net income $96.1M.
Cash flow
In fiscal 2025 operations brought in $83.2M of cash; after $16.3M of capital spending, free cash flow was $66.9M.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 4, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Caris Life Sciences, Inc.'s next report is expected around January 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Caris Life Sciences, Inc. does

Caris Life Sciences, Inc. is registered with the SEC under industry code SIC 8071 (Services-Medical Laboratories). Its shares trade on NASDAQ under the ticker CAI.

Revenue and profit by year

Revenue
FY23: $306.1M $306.1M FY23FY25: $412.3M $412.3M FY25FY25: $812M $812M FY25
Net income
FY23: -$341.4M -$341.4M FY23FY25: -$281.9M -$281.9M FY25FY25: -$68.1M -$68.1M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$812M$45.1M-$68.1M-$3.22$66.9M
2025$412.3M-$257.1M-$281.9M-$10.66-$253.6M
2023$306.1M-$319.6M-$341.4M-$13.24-$298.4M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around January 11, 2027.

Estimated from its filing rhythm: 52 weeks after its report of January 12, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where CAI ranks in Health care

Revenue$812M
#169 of 751 in Health care · Top 22%
Revenue growth+97.0%
#57 of 532 in Health care · Top 11%
Net margin-8.4%
#274 of 544 in Health care · Top 50%
Free cash flow margin8.2%
#148 of 490 in Health care · Top 30%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Caris Life Sciences, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 5, 2026
  2. November 4, 2026
    Quarterly report 10-Q · period to September 30, 2026Revenue rose 27% to $275.4M versus the same quarter last year; diluted EPS $0.05 versus $0.08.
  3. November 4, 2026
  4. September 14, 2026
  5. August 12, 2026
  6. August 7, 2026
  7. August 5, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue rose 45% to $263.7M versus the same quarter last year; diluted EPS $0.00 versus -$7.97.
  8. August 5, 2026
  9. June 5, 2026
  10. May 12, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on September 23, 2026. Insider transactions on SEC

What is CAI worth? A DCF from its reported cash flow

Insider trades

What the people running Caris Life Sciences, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $27.2M worth of shares in the last 90 days and bought none on the open market.

Bought (open market)
$0
last 90 days
Sold
$27.2M
last 90 days
Net sold
1,004,712
$27.2M
DateInsiderWhatSharesPriceValueFiling
September 22, 2026 Denton John RusselSee Remarks Sold 7,500 $31.82 $238.6K Form 4
September 17, 2026 Brille Brian JSee Remarks, Director Exercised options 400,000 $2.44 $976K Form 4
September 17, 2026 Brille Brian JSee Remarks, Director Sold 400,000 $30.33 $12.1M Form 4
September 4, 2026 Spetzler David BaxleyPresident Exercised options 250,000 $2.44 $610K Form 4
September 4, 2026 Spetzler David BaxleyPresident Sold 119,212 $24.76 $3M Form 4
September 3, 2026 Spetzler David BaxleyPresident Exercised options 1,000,000 $2.44 $2.4M Form 4
September 3, 2026 Spetzler David BaxleyPresident Sold 393,100 $24.76 $9.7M Form 4
September 3, 2026 Spetzler David BaxleyPresident Sold 84,900 $25.32 $2.1M Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns CAI

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
David D. Halbert13G, passive with 1 related filers 44.1% 124,906,296 August 13, 2025
Fmr LLC13G, passive with 1 related filers 10.8% 30,631,585 April 7, 2026

Latest filings below 5%: J H Whitney VI L P 4% (August 12, 2026); Alan Waxman 2.6% (August 7, 2026); Millennium Management LLC 1.3% (June 24, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 246 managers reported a position.

HolderSharesValueChange on quarter
Fmr LLC30,923,878$551.1M+138,293
J. H. Whitney Equity Partners VI, LLC11,256,615$200.6M-7,000,000
Coatue Management LLC9,819,992$175M0
Braidwell LP8,256,032$147.1M+246,585
Sixth Street Partners Management Company, L.P.7,327,041$130.6M-7,058,358
PointState Capital LP6,828,835$121.7M-531,611
Jpmorgan Chase & Co6,558,514$120.2M+3,098,299
BlackRock, Inc.5,536,798$98.7M+679,686
Vanguard Portfolio Management LLC4,844,431$86.3M+1,085,969
Vanguard Capital Management LLC4,280,238$76.3M+951,217
Los Angeles Capital Management LLC3,958,531$70.5M+1,668,929
Neuberger Berman Group LLC3,590,963$64M+377
Orbimed Advisors LLC2,806,811$50M0
Bnp Paribas Financial Markets2,370,268$42.2M+755,982
Millennium Management LLC2,202,647$39.3M+674,891
Mak Capital One LLC1,937,229$34.5Mnew
Morgan Stanley1,935,531$34.5M+856,114
Clearbridge Investments, LLC1,595,877$28.4M+44,103
FIL Ltd1,548,918$27.6M+2,827
UBS Group AG1,423,371$25.4M-1,322,440

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

15 insiders reported holding 6,141,540 shares in total, about $150M at the last price.

HolderSharesAs of
Halbert David DSee Remarks, Director, 10% owner 2,574,533 May 15, 2026
Spetzler David BaxleyPresident 1,182,871 September 4, 2026
Halbert JonDirector 836,411704,598 held indirectly August 14, 2026
Johansen Laura IDirector 343,897 August 14, 2026
Knowles Jonathan Kenneth CharlesDirector 308,979 May 29, 2026
Brille Brian JSee Remarks, Director 230,303 September 17, 2026
Denton John RusselSee Remarks 174,855 September 22, 2026
Power Luke ThomasSee Remarks 153,771 May 15, 2026
Phillips T DannyDirector 133,060 August 14, 2026
Vacirca Jeff LDirector 62,863 August 14, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about CAI

What does Caris Life Sciences, Inc. do?

Caris Life Sciences, Inc. is a company in the Health care sector, listed on NASDAQ as CAI. Its shares trade on NASDAQ under the ticker CAI.

What is Caris Life Sciences, Inc.'s net worth?

Caris Life Sciences, Inc. has a market value (market cap) of $6.9B at the latest share price, and shareholders' equity of $639.5M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Caris Life Sciences, Inc. profitable?

Yes. Over the twelve months to September 30, 2026 it reported net income of $96.1M on revenue of $1B, a net margin of 9.2%.

How much revenue does Caris Life Sciences, Inc. make?

Over the twelve months to September 30, 2026 Caris Life Sciences, Inc. reported revenue of $1B.

When did Caris Life Sciences, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 4, 2026. It covers the period to September 30, 2026. Its newest filing of any kind is the passive stake changed from November 5, 2026.

When is Caris Life Sciences, Inc.'s next earnings report?

Caris Life Sciences, Inc.'s next report is expected around January 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Caris Life Sciences, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.