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NASDAQ · Health care

GRAIL, Inc. (GRAL)

GRAIL, Inc. brought in $166.6M of revenue over the twelve months to September 30, 2026, up 17.5% from a year earlier. It posted a net loss of $406.2M. In fiscal 2025 capital spending exceeded operating cash flow by $299.9M. At September 30, 2026 it held $29M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 5, 2026.

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Price
$128.08
+5.47% on the day · November 9, 2026
52-week range $41.50 to $166.48
Market cap
$5.7B
Revenue (last 12 months)
$166.6M
+17.5% year on year
Net margin
-243.8%

Key facts about GRAIL, Inc.

Net worth
GRAIL, Inc. has a market value (market cap) of $5.7B at the latest share price, and shareholders' equity of $2.5B on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $147.2M (+17.2% year on year), with a net loss of $408.4M. Over the 12 months to September 30, 2026: revenue $166.6M, net loss $406.2M.
Cash flow
In fiscal 2025 operations used $299M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 5, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
GRAIL, Inc.'s next report is expected around January 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What GRAIL, Inc. does

GRAIL, Inc. is registered with the SEC under industry code SIC 8071 (Services-Medical Laboratories). Its shares trade on NASDAQ under the ticker GRAL.

Revenue and profit by year

Revenue
FY22: $55.6M $55.6M FY22FY24: $93.1M $93.1M FY24FY24: $125.6M $125.6M FY24FY25: $147.2M $147.2M FY25
Net income
FY22: -$5.4B -$5.4B FY22FY24: -$1.5B -$1.5B FY24FY24: -$2B -$2B FY24FY25: -$408.4M -$408.4M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$147.2M-$562.2M-$408.4M-$11.11-$299.9M
2024$125.6M-$2.2B-$2B-$63.54-$582.4M
2024$93.1M-$1.5B-$1.5B-$47.21-$608.7M
2022$55.6M-$5.4B-$5.4B-$173.89-$584.2M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around January 11, 2027.

Estimated from its filing rhythm: 52 weeks after its report of January 12, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where GRAL ranks in Health care

Revenue$147.2M
#298 of 751 in Health care · Top 40%
Revenue growth+17.2%
#205 of 532 in Health care · Top 38%
Net margin-277.5%
#493 of 544 in Health care · Bottom 9%
Free cash flow margin-203.8%
#440 of 490 in Health care · Bottom 10%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What GRAIL, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 5, 2026
    Quarterly report 10-Q · period to September 30, 2026Revenue rose 3.7% to $37.5M versus the same quarter last year; diluted EPS -$2.21 versus -$2.46.
  2. November 5, 2026
  3. November 4, 2026
  4. August 13, 2026
  5. August 7, 2026
  6. August 6, 2026
  7. August 6, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue rose 26% to $44.7M versus the same quarter last year; diluted EPS -$2.56 versus -$3.18.
  8. August 5, 2026
  9. July 28, 2026
  10. June 22, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 16, 2026. Insider transactions on SEC

Insider trades

What the people running GRAIL, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $14.8M worth of shares in the last 90 days and bought none on the open market. Most of the selling (69%) was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$14.8M
last 90 days
Net sold
129,944
$14.8M
DateInsiderWhatSharesPriceValueFiling
October 15, 2026 Mizell StevenDirector Received as pay 148 $135.46 $20K Form 4
October 15, 2026 Ofman Joshua J.Chief Executive Officer, Director Soldpre-planned (10b5-1) 400 $133.12 $53.2K Form 4
October 15, 2026 Ofman Joshua J.Chief Executive Officer, Director Soldpre-planned (10b5-1) 1,000 $134.38 $134.4K Form 4
October 15, 2026 Ofman Joshua J.Chief Executive Officer, Director Soldpre-planned (10b5-1) 3,400 $135.44 $460.5K Form 4
October 15, 2026 Ofman Joshua J.Chief Executive Officer, Director Soldpre-planned (10b5-1) 7,052 $136.83 $964.9K Form 4
October 15, 2026 Ofman Joshua J.Chief Executive Officer, Director Soldpre-planned (10b5-1) 6,034 $137.63 $830.5K Form 4
October 15, 2026 Ofman Joshua J.Chief Executive Officer, Director Soldpre-planned (10b5-1) 2,114 $138.79 $293.4K Form 4
October 15, 2026 Chase William JDirector Received as pay 153 $135.46 $20.7K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns GRAL

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Baker Bros. Advisors LP13G, passive with 3 related filers 9.8% 4,028,614 May 15, 2026
Farallon Capital Management, L.L.C.13G, passive with 28 related filers 9.6% 4,161,584 August 13, 2026
Dapice Joshua J.13G, passive with 27 related filers 7.8% 3,253,684 May 11, 2026
Primecap Management Co13G, passive 5.08% 21,801,016 August 6, 2026
Crcm LP13G, passive with 8 related filers 5% 1,800,651 October 6, 2025

Latest filings below 5%: The Vanguard Group 0% (March 27, 2026); Sessa Capital (Master), L.P. 4.27% (May 7, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 373 managers reported a position.

HolderSharesValueChange on quarter
Farallon Capital Management, L.L.C.4,161,584$284.1M+907,900
Baker Bros. Advisors LP4,028,614$275M0
BlackRock, Inc.3,577,075$244.2M+608,539
State Street Corp2,385,514$162.9M+493,621
Primecap Management Co2,180,106$148.8M+336,334
Arbiter Partners Capital Management LLC2,068,594$141.2M+1,033,997
Sessa Capital IM, L.P.2,037,518$139.1M+318,204
Deep Track Capital, LP1,834,944$125.3M+112,147
Vanguard Capital Management LLC1,641,117$112M+114,012
Morgan Stanley1,462,163$99.8M-170,032
Geode Capital Management, LLC991,380$67.7M+163,438
Goldman Sachs Group Inc748,015$51.1M+166,091
Jefferies Financial Group Inc.724,000$49.4M+66,500
Bank of America Corp723,437$49.4M-190,677
Dimensional Fund Advisors LP679,587$46.4M+270,937
Casdin Capital, LLC480,000$32.8M+250,000
Vanguard Portfolio Management LLC477,982$32.6M+143,076
Northern Trust Corp372,588$25.4M+23,451
Citigroup Inc371,253$25.3M+69,117
Kingdon Capital Management, L.L.C.340,000$23.2Mnew

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

8 insiders reported holding 1,416,728 shares in total, about $181.5M at the last price.

HolderSharesAs of
Ragusa Robert PChief Executive Officer, Director 518,582 April 8, 2026
Ofman Joshua J.Chief Executive Officer, Director 342,271 October 15, 2026
Freidin AaronChief Financial Officer 225,364 October 5, 2026
Partridge Andrew JohnChief Growth Officer 155,865 October 5, 2026
Summe Gregory LDirector 45,909 October 15, 2026
Chase William JDirector 43,131 October 15, 2026
Mizell StevenDirector 42,978 October 15, 2026
Krevans SarahDirector 42,628 June 18, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about GRAL

What does GRAIL, Inc. do?

GRAIL, Inc. is a company in the Health care sector, listed on NASDAQ as GRAL. Its shares trade on NASDAQ under the ticker GRAL.

What is GRAIL, Inc.'s net worth?

GRAIL, Inc. has a market value (market cap) of $5.7B at the latest share price, and shareholders' equity of $2.5B on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is GRAIL, Inc. profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $406.2M on revenue of $166.6M.

How much revenue does GRAIL, Inc. make?

Over the twelve months to September 30, 2026 GRAIL, Inc. reported revenue of $166.6M. That is 17.5% more than a year earlier.

When did GRAIL, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 5, 2026. It covers the period to September 30, 2026.

When is GRAIL, Inc.'s next earnings report?

GRAIL, Inc.'s next report is expected around January 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values GRAIL, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.