Stocks Comparison
Caris Life Sciences vs Guardant Health: revenue, profit, margins and growth compared
Caris Life Sciences brought in $812M of revenue in fiscal 2025, Guardant Health $982M in fiscal 2025. Revenue changed by +97.0% at Caris Life Sciences and +32.9% at Guardant Health on the year before, so Caris Life Sciences grew faster. Caris Life Sciences kept -8.4% of its revenue as net profit, Guardant Health -42.4%. Free cash flow was $66.9M at Caris Life Sciences and -$233.1M at Guardant Health.
Side by side, latest fiscal year
| CAI | GH | |
|---|---|---|
| Fiscal year ended | FY2025 (December 31, 2025) | FY2025 (December 31, 2025) |
| Revenue | $812M | $982M |
| Revenue growth | +97.0% | +32.9% |
| Net income | -$68.1M | -$416.3M |
| Net margin | -8.4% | -42.4% |
| Free cash flow | $66.9M | -$233.1M |
| Free cash flow margin | 8.2% | -23.7% |
| Earnings per share (diluted) | -$3.22 | -$3.32 |
| Cash | $796.3M | $378.2M |
| Debt | $378.5M | $1.5B |
| Price to earnings | n/a | n/a |
| Market value | $9B | $23.8B |
| Dividend yield | n/a | n/a |
| Rank by revenue in sector | #161 of 523 · Health care | #146 of 523 · Health care |
Over the years
Questions about Caris Life Sciences and Guardant Health
Which is bigger by revenue, Caris Life Sciences or Guardant Health?
Guardant Health is bigger by revenue: $982M in fiscal 2025, against $812M for Caris Life Sciences in fiscal 2025.
Which keeps more of its revenue as profit, Caris Life Sciences or Guardant Health?
Caris Life Sciences had a net margin of -8.4% in fiscal 2025; Guardant Health had -42.4% in fiscal 2025.
Which grew revenue faster, Caris Life Sciences or Guardant Health?
In their latest fiscal years revenue changed by +97.0% at Caris Life Sciences and +32.9% at Guardant Health.
Where do these numbers come from?
From the annual reports each company files with the SEC (10-K, or 20-F and 40-F for foreign companies), read from their XBRL data. Margins and growth are simple arithmetic on those figures. Nothing here is a recommendation.