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What is Vertex Pharmaceuticals Inc / MA worth?

With the base-case assumptions below, a discounted cash flow model on Vertex Pharmaceuticals Inc / MA's reported free cash flow gives $387.95 per share. The share price was $547.89 on November 10, 2026, 41% above that value.

Inputs from the filings

Free cash flow, fiscal 2025
$3.19B
Average free cash flow, last 5 years
$2.41B
Cash
$4.98B
balance sheet of September 30, 2026
Debt
$4.5B
balance sheet of September 30, 2026
Diluted shares, fiscal 2025
258,000,000
Revenue growth per year, last 5 years
14.1%

Three sets of assumptions

CaseGrowth yrs 1-5Growth yrs 6-10After year 10Discount rateValue per shareValue vs price
Bear9.0%5.5%2.0%10.0%$236.73-57%
Base14.0%8.5%2.5%9.0%$387.95-29%
Bull19.0%11.0%3.0%8.0%$669.64+22%

Sensitivity: base case value per share

Discount rate down the side, growth after year 10 across the top. Everything else as in the base case.

1.5%2.0%2.5%3.0%3.5%
7.0%$501.86$537.30$580.62$634.78$704.40
8.0%$416.34$439.33$466.49$499.09$538.93
9.0%$354.10$369.82$387.95$409.10$434.11
10.0%$306.88$318.06$330.72$345.20$361.90
11.0%$269.91$278.11$287.26$297.57$309.24

Where the presets come from

Base: years 1 to 5 grow at Vertex Pharmaceuticals Inc / MA's revenue growth rate over the last 5 fiscal years (14.1% a year), held between -5% and 15%. Years 6 to 10 grow halfway between that and the long-run rate of 2.5%. Future cash is discounted at 9% a year.

Bear: 5 points less growth, 2% long-run growth, 10% discount rate. Bull: 5 points more growth (at most 25%), 3% long-run growth, 8% discount rate.

Value per share = (present value of 10 years of free cash flow + present value of everything after + cash - debt) / diluted shares.

This is a model run on assumptions, not a recommendation or a price target. Small changes in the discount rate or growth move the result a lot, as the table above shows. Change them yourself in the calculator.

Adjust the assumptions

Move the sliders for growth, long-run growth and discount rate, or switch to average free cash flow, and see the value per share change.

Adjust the assumptions

Vertex Pharmaceuticals Inc / MA company page