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Entrada Therapeutics, Inc. (TRDA)

Entrada Therapeutics, Inc. brought in $4M of revenue over the twelve months to September 30, 2026, down 93.5% from a year earlier. It posted a net loss of $161.4M. In fiscal 2025 capital spending exceeded operating cash flow by $129.6M. At September 30, 2026 it held $112.2M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 5, 2026.

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Price
$5.08
+8.28% on the day · November 10, 2026
52-week range $4.11 to $16.45
Market cap
$197.8M
Revenue (last 12 months)
$4M
-93.5% year on year
Net margin
-4,058.0%

Key facts about Entrada Therapeutics, Inc.

Net worth
Entrada Therapeutics, Inc. has a market value (market cap) of $197.8M at the latest share price, and shareholders' equity of $198.3M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $25.4M (-87.9% year on year), with a net loss of $143.8M. Over the 12 months to September 30, 2026: revenue $4M, net loss $161.4M.
Cash flow
In fiscal 2025 operations used $128.5M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 5, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Entrada Therapeutics, Inc.'s next report is expected around January 7, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Entrada Therapeutics, Inc. does

Entrada Therapeutics, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker TRDA.

Revenue and profit by year

Revenue
FY23: $129M $129M FY23FY24: $210.8M $210.8M FY24FY25: $25.4M $25.4M FY25
Net income
FY21: -$26.5M -$26.5M FY21FY21: -$51.2M -$51.2M FY21FY22: -$94.6M -$94.6M FY22FY23: -$6.7M -$6.7M FY23FY24: $65.6M $65.6M FY24FY25: -$143.8M -$143.8M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$25.4M-$157.9M-$143.8M-$3.47-$129.6M
2024$210.8M$47M$65.6M$1.68-$44.7M
2023$129M-$3.2M-$6.7M-$0.20$134.2M
2022n/a-$97.2M-$94.6M-$3.02-$96.7M
2021n/a-$51.1M-$51.2M-$8.16-$55.4M
2021n/a-$26.7M-$26.5M-$24.00-$27.9M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around January 7, 2027.

Estimated from its filing rhythm: 52 weeks after its report of January 8, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where TRDA ranks in Health care

Revenue$25.4M
#458 of 751 in Health care · Bottom 39%
Revenue growth-87.9%
#531 of 532 in Health care · Bottom 1%
Net margin-565.5%
#520 of 544 in Health care · Bottom 4%
Free cash flow margin-509.6%
#472 of 490 in Health care · Bottom 4%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Entrada Therapeutics, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 5, 2026
    Quarterly report 10-Q · period to September 30, 2026Revenue fell 44% to $905K versus the same quarter last year; diluted EPS -$0.94 versus -$1.06.
  2. November 5, 2026
  3. October 14, 2026
  4. September 10, 2026
  5. August 14, 2026
  6. August 5, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue fell 54% to $898K versus the same quarter last year; diluted EPS -$1.01 versus -$1.04.
  7. August 5, 2026
  8. June 10, 2026
  9. May 19, 2026
  10. May 7, 2026
    Quarterly report 10-Q · period to March 31, 2026Revenue fell 96% to $875K versus the same quarter last year; diluted EPS -$0.95 versus -$0.42.

Recent insider filings (Forms 3, 4 and 144): 10, the latest on September 9, 2026. Insider transactions on SEC

Insider trades

What the people running Entrada Therapeutics, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $7.2M worth of shares in the last 90 days and bought none on the open market.

Bought (open market)
$0
last 90 days
Sold
$7.2M
last 90 days
Net sold
991,894
$7.2M
DateInsiderWhatSharesPriceValueFiling
September 9, 2026 MPM BioVentures 2014, L.P.10% owner Soldindirect 28,837 $7.13 $205.6K Form 4
September 9, 2026 Mpm Bioventures 2018, L.P.10% owner Soldindirect 28,837 $7.13 $205.6K Form 4
September 8, 2026 MPM BioVentures 2014, L.P.10% owner Soldindirect 192,500 $7.41 $1.4M Form 4
September 8, 2026 Mpm Bioventures 2018, L.P.10% owner Soldindirect 192,500 $7.41 $1.4M Form 4
September 4, 2026 MPM BioVentures 2014, L.P.10% owner Soldindirect 38,500 $7.11 $273.7K Form 4
September 4, 2026 Mpm Bioventures 2018, L.P.10% owner Soldindirect 38,500 $7.11 $273.7K Form 4
September 3, 2026 MPM BioVentures 2014, L.P.10% owner Soldindirect 32,263 $7.17 $231.3K Form 4
September 3, 2026 Mpm Bioventures 2018, L.P.10% owner Soldindirect 32,263 $7.17 $231.3K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns TRDA

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Baker Bros. Advisors LP13D, may seek influence with 3 related filers 13.2% 4,865,819 June 26, 2024
Kush Parmar13D, may seek influence with 6 related filers 10.8% 4,123,849 November 18, 2025
Ansbert Gadicke13D, may seek influence with 12 related filers 9.9% 3,885,115 September 10, 2026
Roche Finance Ltd13G, passive with 1 related filers 6.9% 2,569,115 February 14, 2025

Latest filings below 5%: TCG Crossover GP I, LLC 2.7% (August 14, 2026); T. Rowe Price Associates, Inc. 0.9% (November 14, 2025); Janus Henderson Group PLC 4% (August 14, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 129 managers reported a position.

HolderSharesValueChange on quarter
Baker Bros. Advisors LP5,072,730$37.3M0
5AM Venture Management, LLC4,056,379$29.9M0
BlackRock, Inc.2,583,333$19M+224,540
Merck & Co., Inc.1,739,768$12.8Mnew
Vanguard Capital Management LLC1,269,634$9.3M+13,621
Mpm Bioimpact LLC1,253,053$9.2Mnew
TCG Crossover Management, LLC1,060,230$7.8M-1,227,270
Wellington Management Group Llp954,419$7M-80,363
Millennium Management LLC763,959$5.6M+244,603
StepStone Group LP761,277$5.6M0
Geode Capital Management, LLC717,430$5.3M+50,083
Aqr Capital Management LLC699,537$5.1M+620,044
Nantahala Capital Management, LLC601,150$4.4M+441,818
State Street Corp596,677$4.4M+62,879
Jpmorgan Chase & Co496,457$3.8M+481,610
Citadel Advisors LLC394,323$2.9M+179,305
Dimensional Fund Advisors LP376,136$2.8M+51,665
Northern Trust Corp309,942$2.3M+74,950
Jacobs Levy Equity Management, Inc303,459$2.2M-30,455
Vanguard Portfolio Management LLC254,130$1.9M+33,636

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

10 insiders reported holding 18,986,605 shares in total, about $96.5M at the last price.

HolderSharesAs of
Baker Bros. Advisors LP10% owner 4,691,3924,691,392 held indirectly November 20, 2025
Mpm Bioventures 2018, L.P.10% owner 3,885,1153,885,115 held indirectly September 9, 2026
MPM BioVentures 2014, L.P.10% owner 3,885,1153,885,115 held indirectly September 9, 2026
5AM Ventures V, L.P.10% owner 2,783,781 August 7, 2026
Parmar KushDirector 2,691,3372,691,337 held indirectly August 10, 2026
Doshi DipalCEO, Director 517,290 September 2, 2026
Sethuraman NatarajanPresident, Research & Develop. 214,238 September 2, 2026
Dowden Nathan JPresident & COO 196,060 September 2, 2026
Wentworth Kory JamesChief Financial Officer 117,277 September 2, 2026
Zeiher Bernhardt GDirector 5,0005,000 held indirectly May 20, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about TRDA

What does Entrada Therapeutics, Inc. do?

Entrada Therapeutics, Inc. is a company in the Health care sector, listed on NASDAQ as TRDA. Its shares trade on NASDAQ under the ticker TRDA.

What is Entrada Therapeutics, Inc.'s net worth?

Entrada Therapeutics, Inc. has a market value (market cap) of $197.8M at the latest share price, and shareholders' equity of $198.3M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Entrada Therapeutics, Inc. profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $161.4M on revenue of $4M.

How much revenue does Entrada Therapeutics, Inc. make?

Over the twelve months to September 30, 2026 Entrada Therapeutics, Inc. reported revenue of $4M. That is 93.5% less than a year earlier.

When did Entrada Therapeutics, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 5, 2026. It covers the period to September 30, 2026.

When is Entrada Therapeutics, Inc.'s next earnings report?

Entrada Therapeutics, Inc.'s next report is expected around January 7, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Entrada Therapeutics, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.