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NASDAQ · Health care

Cue Biopharma, Inc. (CUE)

Cue Biopharma, Inc. brought in $37.7M of revenue over the twelve months to June 30, 2026, up 354.4% from a year earlier. It posted a net loss of $164.1M. In fiscal 2025 capital spending exceeded operating cash flow by $21.9M. At June 30, 2026 it held $17.4M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 14, 2026.

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Price
$18.76
-6.85% on the day · November 10, 2026
52-week range $4.98 to $45.50
Market cap
$136.3M
Revenue (last 12 months)
$37.7M
+354.4% year on year
Net margin
-435.8%

Key facts about Cue Biopharma, Inc.

Net worth
Cue Biopharma, Inc. has a market value (market cap) of $136.3M at the latest share price, and shareholders' equity of $2.3M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $27.5M (+195.7% year on year), with a net loss of $26.6M. Over the 12 months to June 30, 2026: revenue $37.7M, net loss $164.1M.
Cash flow
In fiscal 2025 operations used $21.7M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on August 14, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR
Next earnings report
Cue Biopharma, Inc.'s next report is expected around November 11, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

What Cue Biopharma, Inc. does

Cue Biopharma, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker CUE.

Revenue and profit by year

Revenue
FY18: $1.1M $1.1M FY18FY19: $3.5M $3.5M FY19FY20: $3.2M $3.2M FY20FY21: $14.9M $14.9M FY21FY22: $1.2M $1.2M FY22FY23: $5.5M $5.5M FY23FY24: $9.3M $9.3M FY24FY25: $27.5M $27.5M FY25
Net income
FY18: -$39M -$39M FY18FY19: -$36.7M -$36.7M FY19FY20: -$44.8M -$44.8M FY20FY21: -$44.2M -$44.2M FY21FY22: -$53M -$53M FY22FY23: -$50.7M -$50.7M FY23FY24: -$40.7M -$40.7M FY24FY25: -$26.6M -$26.6M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$27.5M-$26.6M-$26.6M-$0.28-$21.9M
2024$9.3M-$41.5M-$40.7M-$0.72-$36.4M
2023$5.5M-$52.1M-$50.7M-$1.11-$40M
2022$1.2M-$53.2M-$53M-$1.49-$42M
2021$14.9M-$43.7M-$44.2M-$1.41-$39.8M
2020$3.2M-$45M-$44.8M-$1.56-$33.1M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around November 11, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 12, 2025. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where CUE ranks in Health care

Revenue$27.5M
#456 of 751 in Health care · Bottom 39%
Revenue growth+195.7%
#31 of 532 in Health care · Top 6%
Net margin-96.9%
#442 of 544 in Health care · Bottom 19%
Free cash flow margin-79.6%
#399 of 490 in Health care · Bottom 19%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Cue Biopharma, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. October 8, 2026
  2. September 21, 2026
  3. August 21, 2026
  4. August 14, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue rose 167% to $7.9M versus the same quarter last year; diluted EPS -$24.14 versus -$2.67.
  5. August 14, 2026
  6. August 14, 2026
  7. August 12, 2026
  8. August 3, 2026
  9. July 10, 2026
  10. June 18, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 14, 2026. Insider transactions on SEC

Insider trades

What the people running Cue Biopharma, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $1.3M worth of shares in the last 90 days and bought none on the open market.

Bought (open market)
$0
last 90 days
Sold
$1.3M
last 90 days
Net sold
46,790
$1.3M
DateInsiderWhatSharesPriceValueFiling
October 12, 2026 Ray SumitaChief Legal Compliance Officer Sold 1,844 $28.05 $51.7K Form 4
October 12, 2026 Lin Shao-LeeChief Executive Officer, Director Sold 10,000 $27.50 $275K Form 4
October 12, 2026 Lin Shao-LeeChief Executive Officer, Director Sold 1,087 $28.05 $30.5K Form 4
October 12, 2026 Meluzio Michael VincentVP, Prin. Accounting Officer Sold 1,144 $28.05 $32.1K Form 4
August 13, 2026 Ray SumitaChief Legal Compliance Officer Exercised options 18,196 - - Form 4
August 13, 2026 Ray SumitaChief Legal Compliance Officer Sold 2,383 $29.37 $70K Form 4
August 13, 2026 Ray SumitaChief Legal Compliance Officer Sold 6,442 $30.35 $195.5K Form 4
August 13, 2026 Ray SumitaChief Legal Compliance Officer Sold 4 $31.13 $124.5 Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns CUE

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Bleichroeder LP13G, passive with 2 related filers 9.99% 6,127,662 March 21, 2025
Mark E. Strome13G, passive with 5 related filers 8.5% 644,916 October 8, 2026
Driehaus Capital Management LLC13G, passive 6.96% 292,144 August 14, 2026
Shao-Lee Lin13D, may seek influence 6.2% 467,166 August 21, 2026

Latest filings below 5%: Slate Path Capital LP 1.4% (February 14, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 49 managers reported a position.

HolderSharesValueChange on quarter
Bleichroeder LP370,682$11.7Mnew
Driehaus Capital Management LLC292,144$9.2Mnew
Vanguard Capital Management LLC161,700$5.1Mnew
Ikarian Capital, LLC104,364$3.3Mnew
Tetragon Partners GP Ltd93,819$3Mnew
Stempoint Capital LP66,995$2.1Mnew
BlackRock, Inc.57,807$1.8Mnew
ADAR1 Capital Management, LLC55,193$1.7Mnew
Lion Point Capital, LP52,928$1.7Mnew
Squadron Capital Management LLC50,000$1.6Mnew
Diadema Partners LP48,369$1.5Mnew
Geode Capital Management, LLC47,824$1.5Mnew
Boothbay Fund Management, LLC31,459$992.8Knew
UBS Group AG26,700$842.7Knew
Citadel Advisors LLC25,633$809Knew
Vanguard Fiduciary Trust Co24,476$772.5Knew
Texas Capital Bank Wealth Management Services Inc22,881$722.1Knew
Renaissance Technologies LLC14,689$463.6Knew
Persistent Asset Partners Ltd12,332$389.2Knew
Robertson Stephens Wealth Management, LLC11,133$351.4Knew

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

9 insiders reported holding 1,008,121 shares in total, about $18.9M at the last price.

HolderSharesAs of
Lin Shao-LeeChief Executive Officer, Director 694,908 October 12, 2026
Ray SumitaChief Legal Compliance Officer 116,701 October 12, 2026
Meluzio Michael VincentVP, Prin. Accounting Officer 47,817 October 12, 2026
Borie Dominique ChristianChief Medical Officer 31,500 July 13, 2026
Sarraf PashaDirector 29,195 July 9, 2026
Ahlers James MChief Financial Officer 25,500 July 30, 2026
Meehan Viola MongDirector 21,800 July 9, 2026
Camardo Daniel A.Director 21,800 July 9, 2026
Garzone PamelaDirector 18,900 July 9, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about CUE

What does Cue Biopharma, Inc. do?

Cue Biopharma, Inc. is a company in the Health care sector, listed on NASDAQ as CUE. Its shares trade on NASDAQ under the ticker CUE.

What is Cue Biopharma, Inc.'s net worth?

Cue Biopharma, Inc. has a market value (market cap) of $136.3M at the latest share price, and shareholders' equity of $2.3M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Cue Biopharma, Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $164.1M on revenue of $37.7M.

How much revenue does Cue Biopharma, Inc. make?

Over the twelve months to June 30, 2026 Cue Biopharma, Inc. reported revenue of $37.7M. That is 354.4% more than a year earlier.

When did Cue Biopharma, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 14, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the insider trade from October 14, 2026.

When is Cue Biopharma, Inc.'s next earnings report?

Cue Biopharma, Inc.'s next report is expected around November 11, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Cue Biopharma, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.