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NASDAQ · Health care

Milestone Pharmaceuticals Inc. (MIST)

It posted a net loss of $84M. In fiscal 2025 capital spending exceeded operating cash flow by $49.3M. At June 30, 2026 it held $169.7M in cash against $59.2M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 12, 2026.

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Price
$0.69
-6.83% on the day · November 10, 2026
52-week range $0.63 to $3.06
Market cap
$85.7M

Key facts about Milestone Pharmaceuticals Inc.

Net worth
Milestone Pharmaceuticals Inc. has a market value (market cap) of $85.7M at the latest share price, and shareholders' equity of $18.2M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Cash flow
In fiscal 2025 operations used $49M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on August 12, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR
Next earnings report
Milestone Pharmaceuticals Inc.'s next report is expected around November 11, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

What Milestone Pharmaceuticals Inc. does

Milestone Pharmaceuticals Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker MIST.

Revenue and profit by year

Net income
FY19: -$23.2M -$23.2M FY19FY19: -$55.2M -$55.2M FY19FY20: -$50M -$50M FY20FY21: -$42.9M -$42.9M FY21FY22: -$58.4M -$58.4M FY22FY23: -$59.7M -$59.7M FY23FY24: -$41.5M -$41.5M FY24FY25: -$63.1M -$63.1M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025n/a-$62.1M-$63.1M-$0.75-$49.3M
2024n/a-$42.1M-$41.5M-$0.67-$28.9M
2023n/a-$61.1M-$59.7M-$1.39-$46.5M
2022n/a-$59.6M-$58.4M-$1.38-$52.7M
2021n/a-$43.1M-$42.9M-$1.02n/a
2020n/a-$50.7M-$50M-$1.70n/a

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around November 11, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 12, 2025. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Latest SEC filings

What Milestone Pharmaceuticals Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. October 28, 2026
  2. September 3, 2026
  3. August 12, 2026
  4. August 12, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue was $559K; diluted EPS -$0.21 versus -$0.20.
  5. August 7, 2026
  6. June 15, 2026
  7. May 15, 2026
  8. May 13, 2026
  9. May 13, 2026
  10. May 13, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on June 12, 2026. Insider transactions on SEC

Insider trades

What the people running Milestone Pharmaceuticals Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider trades were reported in the last 90 days.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days
DateInsiderWhatSharesPriceValueFiling
April 16, 2026 Oliveto JosephPresident and CEO, Director Soldpre-planned (10b5-1) 36,500 $2.26 $82.5K Form 4
January 26, 2026 Oliveto JosephPresident and CEO, Director Exercised options 66,600 - - Form 4
January 26, 2026 Oliveto JosephPresident and CEO, Director Sold 34,523 $1.93 $66.6K Form 4
January 26, 2026 Muller LorenzChief Commercial Officer Exercised options 20,100 - - Form 4
January 26, 2026 Muller LorenzChief Commercial Officer Sold 11,180 $1.93 $21.6K Form 4
January 26, 2026 Hasija AmitCFO & EVP of Corp. Development Exercised options 20,100 - - Form 4
January 26, 2026 Hasija AmitCFO & EVP of Corp. Development Sold 12,245 $1.93 $23.6K Form 4
January 26, 2026 Bharucha DavidChief Medical Officer Exercised options 20,100 - - Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns MIST

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Propel Bio Management, LLC13G, passive with 3 related filers 9.9% 8,861,186 December 23, 2025
RTW Investments, LP13G, passive with 1 related filers 9.9% 12,356,953 May 15, 2026
Pavaki Capital Management LLC13G, passive with 2 related filers 7.3% 9,067,848 August 7, 2026
Adage Capital Management, L.P.13G, passive with 2 related filers 6.37% 8,000,000 May 13, 2026

Latest filings below 5%: Trails Edge Capital Partners, LP 4.3% (March 26, 2026); Integrated Core Strategies (US) LLC 0.6% (April 30, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 78 managers reported a position.

HolderSharesValueChange on quarter
Pavaki Capital Management LLC9,067,848$12.2M+5,000
Rtw Investments, LP7,833,336$10.5M+1,502,335
Propel Bio Management, LLC7,429,590$10M+3,311,269
Point72 Asset Management, L.P.5,411,138$7.3M+4,325,455
Simplify Asset Management Inc.3,349,379$4.5M+1,842,974
Millennium Management LLC3,142,219$4.2M+1,597,894
Kalehua Capital Management LLC2,538,474$3.4Mnew
Two Sigma Investments, LP2,040,015$2.7M-277,161
Marshall Wace, Llp1,797,695$2.4M-146,835
Lion Point Capital, LP820,000$1.1M0
Toronto Dominion Bank750,000$1M0
Ameriprise Financial Inc666,666$893.3K0
Boxer Capital Management, LLC666,666$893.3K0
Morgan Stanley635,211$851.2K-88,930
UBS Group AG465,403$623.6K-29,505
Boothbay Fund Management, LLC462,669$620K+293,994
Susquehanna International Group, Llp359,895$482.3K-159,151
Aptus Capital Advisors, LLC339,450$454.9K+59,200
Guardian Wealth Advisors, LLC / NC339,450$454.9K+59,200
Seven Fleet Capital Management LP270,233$362.1K-63,100

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

5 insiders reported holding 914,527 shares in total, about $629.2K at the last price.

HolderSharesAs of
Oliveto JosephPresident and CEO, Director 446,244 April 16, 2026
Muller LorenzChief Commercial Officer 205,406 January 26, 2026
Bharucha DavidChief Medical Officer 113,181 January 26, 2026
Hasija AmitCFO & EVP of Corp. Development 99,848 January 26, 2026
Nelson Jeffrey EdwardChief Operating Officer 49,848 January 26, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about MIST

What does Milestone Pharmaceuticals Inc. do?

Milestone Pharmaceuticals Inc. is a company in the Health care sector, listed on NASDAQ as MIST. Its shares trade on NASDAQ under the ticker MIST.

What is Milestone Pharmaceuticals Inc.'s net worth?

Milestone Pharmaceuticals Inc. has a market value (market cap) of $85.7M at the latest share price, and shareholders' equity of $18.2M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Milestone Pharmaceuticals Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $84M.

When did Milestone Pharmaceuticals Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 12, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the stock exchange listing notice from October 28, 2026.

When is Milestone Pharmaceuticals Inc.'s next earnings report?

Milestone Pharmaceuticals Inc.'s next report is expected around November 11, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Milestone Pharmaceuticals Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.