Income statement, balance sheet and cash flow statement for the last 10 fiscal years, taken from the XBRL data SYNLOGIC, INC. files with the SEC in its annual reports.
In USD millions, except per-share amounts. Outflows in the cash flow statement are negative.
Income statement
FY2016
FY2017
FY2018
FY2019
FY2020
FY2021
FY2022
FY2023
FY2024
FY2025
Revenue
0.44
2.44
2.52
2.22
0.55
1.75
1.18
3.37
0.01
0
Research and development
15
30.3
38
41.9
47.5
47.1
52
44
9.15
0.04
General and administrative
6.4
12.9
15.7
14.7
13.5
15.4
16.6
14.6
6.63
3.49
Operating expenses
21.4
43.3
53.8
56.6
61
62.5
68.6
58.5
41
4.01
Operating income
-21
-40.8
-51.2
-54.4
-60.5
-60.8
-67.4
-55.2
-41
-4.01
Interest expense
0.01
0.06
0.04
0.02
0.01
0
0
0
0
Interest income
0.35
Other non-operating income
0.01
0.45
2.8
3.04
1.29
0.2
1.27
-6.1
17.6
3
Pre-tax income
-66.1
-61.3
-23.4
-1.01
Income tax
0
0
0
0
0
0
0.01
0.01
0
Net income
-21
-40.4
-48.4
-51.4
-59.2
-60.6
-66.1
-61.3
-23.4
-1.01
EBITDA
-20.8
-38.5
-48.8
-51.7
-57.8
-58.3
-64.9
-53.2
-40.6
-4.01
EPS, basic
-20.25
-96.44
-32.63
-27.32
-26.52
-17.52
-14.79
-9.42
-1.92
-0.08
EPS, diluted
-20.25
-96.44
-32.63
-27.32
-26.52
-17.52
-14.79
-9.42
-1.92
-0.08
Shares, basic (weighted)
1.3
0.42
1.49
1.88
2.23
3.44
4.47
6.5
12.2
12.3
Shares, diluted (weighted)
1.3
0.42
1.49
1.88
2.23
3.44
4.47
6.5
12.2
12.3
Balance sheet
FY2016
FY2017
FY2018
FY2019
FY2020
FY2021
FY2022
FY2023
FY2024
FY2025
Cash and equivalents
14.6
58.4
11.3
26.2
32.5
16.4
15.9
24
18.9
14.7
Short-term investments
28.6
111
93.4
67.9
112
61.8
23.8
0
Other current assets
0.03
0.3
0.39
0.65
0.25
0.31
0.18
0.15
0.08
0.05
Total current assets
16.1
88.6
124
133
107
133
79.8
49.9
19.8
15.4
Property, plant and equipment
3.5
9.78
14.8
13
10.8
9.09
7.32
5.6
0
Lease right-of-use assets
17.3
15.5
13.9
14.4
12.1
0
Long-term investments
7.5
8.04
Other non-current assets
0.42
0.23
0.06
0.06
0
0
0.01
0.02
0
Total assets
20
99.7
140
189
144
175
111
75.6
19.8
15.4
Accounts payable
0.99
2.68
2.42
2.17
2
1.94
1.79
1.46
0.16
0.1
Accrued liabilities
2.3
4.82
4.99
3.95
3.77
4.4
5.29
3
2.04
0.92
Deferred revenue
0.44
0.44
0.27
0.54
0.53
0.88
0
Total current liabilities
4.19
9.03
8.34
8.86
8.3
10.1
12.1
30.3
7.08
3.58
Lease liabilities
22.8
20.3
17.4
16.1
12.5
0
Other non-current liabilities
0.13
Total liabilities
3.81
14.7
16.2
31.7
28.7
27.5
28.3
42.8
7.08
3.58
Paid-in capital
163
157
244
328
345
438
442
454
457
457
Retained earnings
-31.2
-71.7
-120
-171
-230
-291
-357
-418
-442
-443
Treasury stock
-2.52
-2.52
-2.52
-2.52
Other comprehensive income
-103
-0.01
-0.07
0.11
0.01
-0.05
-0.16
0.01
0
0
Shareholders' equity
8.5
85
124
157
115
147
82.6
32.8
12.8
11.9
Total equity
8.5
85
124
157
115
147
82.6
32.8
12.8
11.9
Total liabilities and equity
20
99.7
140
189
144
175
111
75.6
19.8
15.4
Shares outstanding
0
1.01
1.58
2.01
2.38
4.34
4.16
9.19
11.7
11.7
Cash flow statement
FY2016
FY2017
FY2018
FY2019
FY2020
FY2021
FY2022
FY2023
FY2024
FY2025
Net income
-21
-40.4
-48.4
-51.4
-59.2
-60.6
-66.1
-61.3
-23.4
-1.01
Depreciation and amortization
0.16
2.31
2.42
2.7
2.64
2.44
2.52
1.96
0.35
0
Stock-based compensation
0.37
2.65
4.32
4.13
3.91
3.36
3.64
2.81
3.17
0.12
Change in payables
-3.26
4.07
-0.26
-0.94
-0.35
0.54
0.7
-2.65
-2.26
-1.18
Cash from operations
-20.4
-31.1
-42.5
-75.5
-39.6
-52.2
-56.9
-51.6
-31.7
-4.36
Capital expenditures
-1.84
-2.58
-5.65
-1.25
-0.4
-0.68
-0.73
-0.21
-0.01
0
Purchases of investments
-51.4
-173
-145
-86.5
-168
-82.8
-27.9
-1.48
0
Sales and maturities of investments
58.8
22.9
91.3
157
28.5
1.27
0
66.9
25.5
0
Cash from investing
-1.83
9.28
-87.2
10.8
32.5
-53.3
58.4
38.8
25.3
0.17
Stock issued
0
0.01
82.7
57
81
0
Share buybacks
0
-2.52
0
Cash from financing
30.6
66.7
82.5
79.6
13.4
89.4
-2.04
20.9
0.17
0
Net change in cash
8.41
44.9
-47.2
14.9
6.32
-16.1
-0.58
8.1
-6.15
-4.19
Free cash flow
-22.2
-33.6
-48.1
-76.7
-39.9
-52.9
-57.6
-51.8
-31.7
-4.36
Interest paid
0.01
0.04
0.04
0.02
0.01
0
0
0
0
Income taxes paid
0
0.01
0.01
0
Key metrics
Worked out from the statements above. Latest values use the trailing twelve months to June 30, 2026; growth uses fiscal years. Valuation uses the share price of $1.15 on September 28, 2026.
Profitability
Metric
Value
How it is calculated
Return on equity (ROE)
-5.5%
Net income / average shareholders' equity (opening and closing). Not shown when equity is negative.
Return on assets (ROA)
-4.9%
Net income / average total assets.
Growth
Metric
Value
How it is calculated
Revenue growth, 1y
-100.0%
Revenue vs the same period a year earlier. Only from a positive base.
Book value growth, 1y
-7.0%
Book value vs the same period a year earlier. Only from a positive base.
Book value CAGR, 3y
-47.6%
Compound annual growth of book value over 3 fiscal years: (end / start)^(1/3) - 1. Only when both values are positive.
Book value CAGR, 5y
-36.5%
Compound annual growth of book value over 5 fiscal years: (end / start)^(1/5) - 1. Only when both values are positive.
Total assets growth, 1y
-22.1%
Total assets vs the same period a year earlier. Only from a positive base.
Total assets CAGR, 3y
-48.2%
Compound annual growth of total assets over 3 fiscal years: (end / start)^(1/3) - 1. Only when both values are positive.
Total assets CAGR, 5y
-36.0%
Compound annual growth of total assets over 5 fiscal years: (end / start)^(1/5) - 1. Only when both values are positive.
Share count change, 1y
0.9%
Change in diluted weighted shares vs a year earlier. Negative means buybacks shrank the share count; positive means dilution.
Share count change per year, 3y
40.2%
Change in diluted weighted shares, per year over 3 years. Negative means buybacks shrank the share count; positive means dilution.
Share count change per year, 5y
40.7%
Change in diluted weighted shares, per year over 5 years. Negative means buybacks shrank the share count; positive means dilution.
Balance sheet health
Metric
Value
How it is calculated
Current ratio
9.19x
Current assets / current liabilities.
Quick ratio
9.02x
(Cash + short-term investments + receivables) / current liabilities.
Cash ratio
9.02x
(Cash + short-term investments) / current liabilities.
Net income per diluted share, as reported (split-adjusted). Over the last twelve months: the four quarters summed, or net income / latest diluted shares when a quarter has no reported EPS.
Revenue per share
$0.00
Revenue / diluted weighted shares.
Operating cash flow per share
-$0.31
Cash from operations / diluted weighted shares.
Book value per share
$1.03
Shareholders' equity / shares outstanding (diluted weighted shares when not reported).
Market cap + total debt - cash - short-term investments.
P/B
1.17x
Market cap / shareholders' equity. Only when equity is positive.
Price / tangible book
1.17x
Market cap / tangible book value, when positive.
Earnings yield
-4.6%
Net income / market cap (the inverse of P/E).
What was SYNLOGIC, INC.'s revenue in fiscal 2025?
SYNLOGIC, INC. reported revenue of $0.0 for fiscal 2025, 100% lower than the year before.
Was SYNLOGIC, INC. profitable in fiscal 2025?
No. It reported a net loss of $1.0M.
How much free cash flow did SYNLOGIC, INC. generate in fiscal 2025?
Cash from operations of $4.4M minus capital expenditures of $0.0 left free cash flow of -$4.4M.
Source: SEC EDGAR XBRL company facts. Where a company tags only year-to-date figures, quarters are worked out as differences. Where a line is not tagged it is left empty, never estimated.