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NASDAQ · Health care

Silence Therapeutics plc (SLN)

Silence Therapeutics plc brought in $615K of revenue over the twelve months to June 30, 2026, down 97.7% from a year earlier. It posted a net loss of $60M. In fiscal 2025 capital spending exceeded operating cash flow by $62.3M. At June 30, 2026 it held $72.1M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 10, 2026.

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Price
$11.20
+0.18% on the day · September 28, 2026
52-week range $4.19 to $17.58
Market cap
$524.2M
Revenue (last 12 months)
$615K
-97.7% year on year
Net margin
-9,748.5%

What Silence Therapeutics plc does

Silence Therapeutics plc is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker SLN.

Revenue and profit by year

Revenue
FY22: $21.7M $21.7M FY22FY24: $31.6M $31.6M FY24FY24: $43.3M $43.3M FY24FY25: $559K $559K FY25
Net income
FY22: -$50.3M -$50.3M FY22FY24: -$54.2M -$54.2M FY24FY24: -$45.3M -$45.3M FY24FY25: -$88.6M -$88.6M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$559K-$91.1M-$88.6M-$0.63-$62.3M
2024$43.3M-$63.3M-$45.3M-$0.33-$67.9M
2024$31.6M-$64.4M-$54.2M-$0.49-$49.5M
2022$21.7M-$61M-$50.3M-$0.52-$57.2M

Full financial statements: income, balance sheet and cash flow

Next report expected around November 5, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 6, 2025. Not a date the company has announced. See the report calendar

Where SLN ranks in Health care

Revenue$559K
#671 of 742 in Health care · Bottom 10%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Silence Therapeutics plc has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. August 13, 2026
  2. August 13, 2026
  3. August 12, 2026
  4. August 12, 2026
  5. August 11, 2026
  6. August 10, 2026
  7. August 10, 2026
  8. August 10, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$0.09 versus -$0.19.
  9. August 10, 2026
  10. July 16, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on August 13, 2026. Insider transactions on SEC

Insider trades

What the people running Silence Therapeutics plc did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider trades were reported in the last 90 days.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns SLN

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Richard Ian Griffiths13D, may seek influence with 1 related filers 16.9% 23,709,102 March 27, 2024
Richard Griffiths13D, may seek influence 7.97% 14,391,498 August 13, 2026
Raymond Debbane13G, passive with 7 related filers 7% 9,934,314 August 13, 2026

Latest filings below 5%: Lombard Odier Asset Management (USA) Corp 4.2% (February 9, 2026); Redmile Group, LLC 4.7% (May 15, 2025); Deep Track Capital, LP 2.14% (November 14, 2024).

Largest institutional holders

No Form 13F positions imported for this company yet.

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

No insider reported holdings on a Form 4 in the last 12 months.

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about SLN

What does Silence Therapeutics plc do?

Silence Therapeutics plc is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker SLN.

Is Silence Therapeutics plc profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $60M on revenue of $615K.

How much revenue does Silence Therapeutics plc make?

Over the twelve months to June 30, 2026 Silence Therapeutics plc reported revenue of $615K. That is 97.7% less than a year earlier.

When did Silence Therapeutics plc last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 10, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the activist stake changed from August 13, 2026.

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Where the numbers come from

Financial figures are the values Silence Therapeutics plc tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.