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NASDAQ · Health care

Design Therapeutics, Inc. (DSGN)

It posted a net loss of $74.1M. In fiscal 2025 capital spending exceeded operating cash flow by $54.6M. At September 30, 2026 it held $15.3M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 4, 2026.

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Price
$10.80
+5.78% on the day · November 9, 2026
52-week range $6.68 to $17.25
Market cap
$675.9M

Key facts about Design Therapeutics, Inc.

Net worth
Design Therapeutics, Inc. has a market value (market cap) of $675.9M at the latest share price, and shareholders' equity of $202.2M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $0, with a net loss of $69.8M.
Cash flow
In fiscal 2025 operations used $54.4M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 4, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Design Therapeutics, Inc.'s next report is expected around March 8, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Design Therapeutics, Inc. does

Design Therapeutics, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker DSGN.

Revenue and profit by year

Revenue
FY21: $226K $226K FY21FY24: $0 $0 FY24FY25: $0 $0 FY25
Net income
FY21: -$8.3M -$8.3M FY21FY21: -$35.5M -$35.5M FY21FY22: -$63.3M -$63.3M FY22FY23: -$66.9M -$66.9M FY23FY24: -$49.6M -$49.6M FY24FY25: -$69.8M -$69.8M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$0-$79.5M-$69.8M-$1.22-$54.6M
2024$0-$62.4M-$49.6M-$0.88-$43.4M
2023n/a-$78.2M-$66.9M-$1.19-$58.8M
2022n/a-$67.6M-$63.3M-$1.14-$52.2M
2021n/a-$35.8M-$35.5M-$0.77-$30.9M
2021$226K-$8.3M-$8.3M-$0.52-$8.7M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around March 8, 2027.

Estimated from its filing rhythm: 52 weeks after its report of March 9, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Latest SEC filings

What Design Therapeutics, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 4, 2026
  2. November 4, 2026
    Quarterly report 10-Q · period to September 30, 2026Diluted EPS -$0.32 versus -$0.30.
  3. November 4, 2026
  4. August 14, 2026
  5. August 14, 2026
  6. August 3, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$0.32 versus -$0.34.
  7. August 3, 2026
  8. June 11, 2026
  9. June 9, 2026
  10. May 18, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on June 11, 2026. Insider transactions on SEC

Insider trades

What the people running Design Therapeutics, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider trades were reported in the last 90 days.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns DSGN

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Simeon George13D, may seek influence with 3 related filers 10.7% 6,607,892 March 11, 2026
Sirenia Capital Management LP13G, passive with 1 related filers 9.5% 5,963,936 August 14, 2026
Light Irrevocable Trust #1 dated April 22, 201913G, passive with 1 related filers 6.9% 3,834,355 February 7, 2025
Star Irrevocable Trust #1 dated April 22, 201913G, passive with 1 related filers 6.9% 3,834,355 February 7, 2025

Latest filings below 5%: Point72 Asset Management, L.P. 3.8% (August 14, 2026); Arsani William 4.4% (November 18, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 137 managers reported a position.

HolderSharesValueChange on quarter
SR One Capital Management, LP6,526,476$94.4M0
Logos Global Management LP3,000,000$43.4M+1,050,000
Baker Bros. Advisors LP2,678,430$38.8M+92,452
Driehaus Capital Management LLC2,661,115$38.5M+916,128
BlackRock, Inc.2,660,024$38.5M+526,260
Point72 Asset Management, L.P.2,366,453$34.2M-356,301
Trails Edge Capital Partners, LP2,001,282$29M+1,149,269
Frazier Life Sciences Management, L.P.1,809,854$26.2Mnew
Vivo Capital, LLC1,612,903$23.3M0
Vanguard Capital Management LLC1,571,022$22.7M+221,172
Caption Management, LLC1,118,098$16.2M+1,031,390
Almitas Capital LLC1,026,893$14.9M-503,442
Geode Capital Management, LLC958,417$13.9M+265,899
Sofinnova Investments, Inc.865,135$12.5Mnew
Fmr LLC776,462$11.2M-21,949
Morgan Stanley765,425$11.1M+108,860
State Street Corp736,221$10.7M+76,646
Woodline Partners LP700,354$10.1M-261,147
Dimensional Fund Advisors LP694,743$10.1M+262,903
Goldman Sachs Group Inc656,584$9.5M+151,866

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

No insider reported holdings on a Form 4 in the last 12 months.

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about DSGN

What does Design Therapeutics, Inc. do?

Design Therapeutics, Inc. is a company in the Health care sector, listed on NASDAQ as DSGN. Its shares trade on NASDAQ under the ticker DSGN.

What is Design Therapeutics, Inc.'s net worth?

Design Therapeutics, Inc. has a market value (market cap) of $675.9M at the latest share price, and shareholders' equity of $202.2M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Design Therapeutics, Inc. profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $74.1M.

When did Design Therapeutics, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 4, 2026. It covers the period to September 30, 2026.

When is Design Therapeutics, Inc.'s next earnings report?

Design Therapeutics, Inc.'s next report is expected around March 8, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Design Therapeutics, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.