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NASDAQ · Health care

Q32 Bio Inc. (QTTB)

In fiscal 2025 capital spending exceeded operating cash flow by $33.5M. At September 30, 2026 it held $289.6M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 4, 2026.

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Price
$9.33
-0.11% on the day · November 10, 2026
52-week range $1.91 to $23.57
Market cap
$277.7M
P/E
3.9
on FY2025 diluted EPS

Key facts about Q32 Bio Inc.

Net worth
Q32 Bio Inc. has a market value (market cap) of $277.7M at the latest share price, and shareholders' equity of $287.7M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $53.7M, with net income of $29.8M.
Cash flow
In fiscal 2025 operations used $33.5M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 4, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Q32 Bio Inc.'s next report is expected around March 9, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Q32 Bio Inc. does

Q32 Bio Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker QTTB.

Revenue and profit by year

Revenue
FY18: $5.3M $5.3M FY18FY19: $1.7M $1.7M FY19FY20: $2.7M $2.7M FY20FY21: $34M $34M FY21FY22: $3.2M $3.2M FY22FY23: $1.2M $1.2M FY23FY24: $0 $0 FY24FY25: $53.7M $53.7M FY25
Net income
FY18: -$55.6M -$55.6M FY18FY19: -$103.9M -$103.9M FY19FY20: -$128.7M -$128.7M FY20FY21: -$95.8M -$95.8M FY21FY22: -$5M -$5M FY22FY23: -$53.7M -$53.7M FY23FY24: -$47.7M -$47.7M FY24FY25: $29.8M $29.8M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$53.7M$16.9M$29.8M$2.42-$33.5M
2024$0-$66.1M-$47.7M-$6.58-$67.8M
2023$1.2M-$48.3M-$53.7M-$153.96-$18.7M
2022$3.2M-$133.3M-$5M-$7.11-$114.9M
2021$34M-$95.9M-$95.8M-$136.59-$112.1M
2020$2.7M-$130.3M-$128.7M-$221.07-$98.1M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around March 9, 2027.

Estimated from its filing rhythm: 52 weeks after its report of March 10, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where QTTB ranks in Health care

Revenue$53.7M
#389 of 751 in Health care · Bottom 48%
Net margin55.5%
#12 of 544 in Health care · Top 2%
Free cash flow margin-62.4%
#390 of 490 in Health care · Bottom 20%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Q32 Bio Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 6, 2026
  2. November 6, 2026
  3. November 4, 2026
    Quarterly report 10-Q · period to September 30, 2026Diluted EPS -$0.26 versus -$0.60.
  4. November 4, 2026
  5. October 28, 2026
  6. October 9, 2026
  7. September 30, 2026
  8. September 14, 2026
  9. August 14, 2026
  10. August 14, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 14, 2026. Insider transactions on SEC

Insider trades

What the people running Q32 Bio Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $320.4K worth of shares in the last 90 days and bought none on the open market.

Bought (open market)
$0
last 90 days
Sold
$320.4K
last 90 days
Net sold
22,054
$320.4K
DateInsiderWhatSharesPriceValueFiling
October 6, 2026 Kalowski LeeCFO and President Sold 1,301 $8.32 $10.8K Form 4
October 6, 2026 Violette Shelia M.Chief Scientific Officer Sold 917 $8.32 $7.6K Form 4
October 6, 2026 Morrison Jodie PopeCEO, Director Sold 3,221 $8.32 $26.8K Form 4
August 25, 2026 Violette Shelia M.Chief Scientific Officer Sold 2,798 $16.56 $46.3K Form 4
August 25, 2026 Morrison Jodie PopeCEO, Director Sold 9,845 $16.56 $163K Form 4
August 25, 2026 Kalowski LeeCFO and President Sold 3,972 $16.56 $65.8K Form 4
July 16, 2026 Kalowski LeeCFO and President Received as pay 53,250 - - Form 4
July 16, 2026 Morrison Jodie PopeCEO, Director Received as pay 132,000 - - Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns QTTB

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Orbimed Advisors LLC13D, may seek influence with 2 related filers 13.9% 4,127,987 July 20, 2026
Bvf Partners L P13G, passive with 9 related filers 9.99% 2,367,524 June 4, 2026
RA Capital Management, L.P.13G, passive with 3 related filers 9.8% 2,332,457 June 4, 2026
Boxer Capital Management, LLC13G, passive with 3 related filers 7.9% 2,357,922 November 6, 2026
Bank of America Corp13G, passive 7.4% 2,205,390 October 28, 2026
Acorn Bioventures, L.P.13D, may seek influence with 2 related filers 6.7% - April 4, 2024
Frazier Life Sciences Public Fund, L.P.13G, passive with 8 related filers 5.9% 1,755,116 October 9, 2026

Latest filings below 5%: Opaleye Management Inc. 3.76% (November 6, 2026); Point72 Asset Management, L.P. 4.95% (August 14, 2026); Sirenia Capital Management LP 0% (August 14, 2026); Atlas Venture Fund X, L.P. 3.6% (May 28, 2026); Sio Capital Management, LLC 0% (April 8, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 71 managers reported a position.

HolderSharesValueChange on quarter
Orbimed Advisors LLC4,127,987$52.6M+1,875,000
Boxer Capital Management, LLC3,149,310$40.1Mnew
Atlas Venture Life Science Advisors, LLC2,717,106$34.6M+625,000
Bvf Inc2,350,000$29.9Mnew
RA Capital Management, L.P.2,332,457$29.7Mnew
Point72 Asset Management, L.P.1,173,396$14.9Mnew
Opaleye Management Inc.931,000$11.9M-325,228
Logos Global Management LP800,000$10.2Mnew
SummitTX Capital, L.P.733,774$9.3Mnew
Vanguard Capital Management LLC518,803$6.6M+212,402
Ikarian Capital, LLC430,000$5.5Mnew
Woodline Partners LP286,212$3.6Mnew
American Century Companies Inc272,752$3.5M+253,982
Sanofi244,083$3.1M0
Acorn Capital Advisors, LLC216,171$2.8M-98,881
Renaissance Technologies LLC179,600$2.3M-27,315
Jane Street Group, LLC162,747$2.1M+97,148
Monimus Capital Management, LP132,036$1.7M-2,274
Boothbay Fund Management, LLC130,427$1.7Mnew
Geode Capital Management, LLC122,690$1.6M+4,538

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

6 insiders reported holding 1,907,583 shares in total, about $17.8M at the last price.

HolderSharesAs of
Orbimed Advisors LLCDirector, 10% owner 625,000625,000 held indirectly May 28, 2026
Xu DiyongDirector, 10% owner 625,000625,000 held indirectly May 28, 2026
Morrison Jodie PopeCEO, Director 340,038 October 6, 2026
Kalowski LeeCFO and President 137,170 October 6, 2026
Violette Shelia M.Chief Scientific Officer 126,854 October 6, 2026
Manke IsaacDirector 53,521 June 30, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about QTTB

What does Q32 Bio Inc. do?

Q32 Bio Inc. is a company in the Health care sector, listed on NASDAQ as QTTB. Its shares trade on NASDAQ under the ticker QTTB.

What is Q32 Bio Inc.'s net worth?

Q32 Bio Inc. has a market value (market cap) of $277.7M at the latest share price, and shareholders' equity of $287.7M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Q32 Bio Inc. profitable?

Yes. Over the twelve months to September 30, 2026 it reported net income of $32.3M.

When did Q32 Bio Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 4, 2026. It covers the period to September 30, 2026. Its newest filing of any kind is the passive stake changed from November 6, 2026.

When is Q32 Bio Inc.'s next earnings report?

Q32 Bio Inc.'s next report is expected around March 9, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Q32 Bio Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.