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NASDAQ · Health care

Pyxis Oncology, Inc. (PYXS)

It posted a net loss of $88.7M. In fiscal 2025 capital spending exceeded operating cash flow by $63.5M. At June 30, 2026 it held $18.9M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 13, 2026.

Price
$2.86
-2.06% on the day · September 25, 2026
52-week range $1.03 to $5.55
Market cap
$238.5M

What Pyxis Oncology, Inc. does

Pyxis Oncology, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker PYXS.

Revenue and profit by year

Revenue
FY24: $16.1M $16.1M FY24FY25: $13.9M $13.9M FY25
Net income
FY21: -$12.8M -$12.8M FY21FY21: -$76M -$76M FY21FY22: -$120.7M -$120.7M FY22FY23: -$73.8M -$73.8M FY23FY24: -$77.3M -$77.3M FY24FY25: -$79.6M -$79.6M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$13.9M-$84.4M-$79.6M-$1.28-$63.5M
2024$16.1M-$89.5M-$77.3M-$1.32-$57.9M
2023n/a-$82.2M-$73.8M-$1.85-$77.4M
2022n/a-$123.5M-$120.7M-$3.65-$95.7M
2021n/a-$69.7M-$76M-$8.95-$35.9M
2021n/a-$12.9M-$12.8M-$12.45-$11.6M
Next report expected around November 2, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 3, 2025. Not a date the company has announced. See the report calendar

Where PYXS ranks in Health care

Revenue$13.9M
#423 of 523 in Health care · Bottom 19%
Revenue growth-14.2%
#394 of 437 in Health care · Bottom 10%
Net margin-574.5%
#426 of 447 in Health care · Bottom 5%
Free cash flow margin-458.3%
#388 of 408 in Health care · Bottom 5%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Pyxis Oncology, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. September 9, 2026
  2. September 8, 2026
  3. August 28, 2026
  4. August 20, 2026
  5. August 13, 2026
    Quarterly report 10-Q · period to June 30, 2026
  6. August 13, 2026
  7. July 10, 2026
  8. July 2, 2026
  9. July 2, 2026
  10. June 15, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on September 8, 2026. Insider transactions on SEC

Insider trades

What the people running Pyxis Oncology, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider trades were reported in the last 90 days.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days

All insider filings on SEC.gov · Where insiders are buying across the market

All filings on SEC EDGAR

Questions about PYXS

What does Pyxis Oncology, Inc. do?

Pyxis Oncology, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker PYXS.

Is Pyxis Oncology, Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $88.7M.

When did Pyxis Oncology, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 13, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the investor disclosure from September 9, 2026.

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Where the numbers come from

Financial figures are the values Pyxis Oncology, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.