Income statement, balance sheet and cash flow statement for the last 6 fiscal years, taken from the XBRL data Nautilus Biotechnology, Inc. files with the SEC in its annual reports.
In USD millions, except per-share amounts. Outflows in the cash flow statement are negative.
Income statement
FY2020
FY2021
FY2022
FY2023
FY2024
FY2025
Research and development
12.4
29.4
37.7
47.3
50.5
41.1
General and administrative
3.31
21.1
25.9
28.9
31
25.7
Operating expenses
15.7
50.5
63.6
76.2
81.5
66.8
Other non-operating income
0.13
0.18
5.69
12.5
10.7
7.84
Income tax
0
0
0
0
0
0
Net income
-15.6
-50.3
-57.9
-63.7
-70.8
-59
EPS, basic
-0.54
-0.60
-0.46
-0.51
-0.56
-0.47
EPS, diluted
-0.54
-0.60
-0.46
-0.51
-0.56
-0.47
Shares, basic (weighted)
29.1
84.5
125
125
125
126
Shares, diluted (weighted)
29.1
84.5
125
125
125
126
Balance sheet
FY2020
FY2021
FY2022
FY2023
FY2024
FY2025
Cash and equivalents
36.6
186
115
19.4
27.6
12.4
Short-term investments
40.1
160
69.9
154
102
91
Other current assets
0.92
3.49
2.74
3.42
2.93
2.56
Total current assets
77.7
349
187
177
133
106
Property, plant and equipment
1.37
2.48
3.7
4.27
4.08
3.46
Lease right-of-use assets
4.84
29.4
28.9
32.6
28.3
27.8
Long-term investments
0
16.4
129
90.6
76.4
52.7
Other non-current assets
1.14
1
1.11
1.18
1.18
1.18
Total assets
85
398
350
306
243
191
Accounts payable
0.47
1.72
1.27
1.64
0.99
0.94
Accrued liabilities
0.39
1.47
1.67
2.59
1.34
2.51
Total current liabilities
3.02
5.81
6.79
9.12
7.63
7.95
Lease liabilities
3.3
29.1
28.3
31.1
26.4
26.2
Total liabilities
6.31
34.9
35.1
40.2
34
34.1
Paid-in capital
0.6
444
455
468
482
489
Retained earnings
-30.3
-80.6
-139
-202
-273
-332
Other comprehensive income
0
-0.18
-1.85
-0.26
0.06
0.24
Shareholders' equity
-29.7
364
315
265
209
157
Total equity
-29.7
364
315
265
209
157
Total liabilities and equity
85
398
350
306
243
191
Shares outstanding
33.1
124
125
125
126
126
Cash flow statement
FY2020
FY2021
FY2022
FY2023
FY2024
FY2025
Net income
-15.6
-50.3
-57.9
-63.7
-70.8
-59
Depreciation and amortization
0.71
1.02
1.22
1.85
2
1.7
Stock-based compensation
0.37
7.93
10.4
12.1
12.7
6.84
Change in payables
0.12
1.26
-0.56
0.39
-0.58
-0.07
Cash from operations
-14
-39.2
-45.8
-51.7
-59.1
-50.7
Capital expenditures
-0.92
-2.27
-2.32
-2.44
-2.12
-1.28
Acquisitions
0
-0.76
0
Purchases of investments
-68.4
-222
-187
-113
-86.3
-72.5
Cash from investing
-25.3
-139
-25.7
-43.7
66.3
35.2
Stock issued
0.04
0.17
0.33
0.1
0.62
0.06
Cash from financing
75.9
327
0.56
0.37
1.14
0.21
Net change in cash
36.6
149
-71
-95.1
8.25
-15.3
Free cash flow
-14.9
-41.5
-48.1
-54.2
-61.3
-52
Key metrics
Worked out from the statements above. Latest values use the trailing twelve months to June 30, 2026; growth uses fiscal years. Valuation uses the share price of $0.96 on September 25, 2026.
Profitability
Metric
Value
How it is calculated
Return on equity (ROE)
-43.1%
Net income / average shareholders' equity (opening and closing). Not shown when equity is negative.
Return on assets (ROA)
-34.6%
Net income / average total assets.
Growth
Metric
Value
How it is calculated
Book value growth, 1y
-24.8%
Book value vs the same period a year earlier. Only from a positive base.
Book value CAGR, 3y
-20.7%
Compound annual growth of book value over 3 fiscal years: (end / start)^(1/3) - 1. Only when both values are positive.
Total assets growth, 1y
-21.3%
Total assets vs the same period a year earlier. Only from a positive base.
Total assets CAGR, 3y
-18.3%
Compound annual growth of total assets over 3 fiscal years: (end / start)^(1/3) - 1. Only when both values are positive.
Total assets CAGR, 5y
17.6%
Compound annual growth of total assets over 5 fiscal years: (end / start)^(1/5) - 1. Only when both values are positive.
Share count change, 1y
0.7%
Change in diluted weighted shares vs a year earlier. Negative means buybacks shrank the share count; positive means dilution.
Share count change per year, 3y
0.4%
Change in diluted weighted shares, per year over 3 years. Negative means buybacks shrank the share count; positive means dilution.
Share count change per year, 5y
34.1%
Change in diluted weighted shares, per year over 5 years. Negative means buybacks shrank the share count; positive means dilution.
Balance sheet health
Metric
Value
How it is calculated
Current ratio
10.1x
Current assets / current liabilities.
Quick ratio
9.73x
(Cash + short-term investments + receivables) / current liabilities.
Cash ratio
9.73x
(Cash + short-term investments) / current liabilities.
Net income per diluted share, as reported (split-adjusted). Over the last twelve months: the four quarters summed, or net income / latest diluted shares when a quarter has no reported EPS.
FCF per share
-$0.41
Free cash flow / diluted weighted shares.
Operating cash flow per share
-$0.40
Cash from operations / diluted weighted shares.
Book value per share
$1.03
Shareholders' equity / shares outstanding (diluted weighted shares when not reported).
Market cap + total debt - cash - short-term investments.
P/B
0.93x
Market cap / shareholders' equity. Only when equity is positive.
Price / tangible book
0.93x
Market cap / tangible book value, when positive.
FCF yield
-42.3%
Free cash flow / market cap.
Earnings yield
-46.1%
Net income / market cap (the inverse of P/E).
Was Nautilus Biotechnology, Inc. profitable in fiscal 2025?
No. It reported a net loss of $59.0M.
How much free cash flow did Nautilus Biotechnology, Inc. generate in fiscal 2025?
Cash from operations of $50.7M minus capital expenditures of $1.3M left free cash flow of -$52.0M.
Source: SEC EDGAR XBRL company facts. Where a company tags only year-to-date figures, quarters are worked out as differences. Where a line is not tagged it is left empty, never estimated.