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NASDAQ · Health care

Mineralys Therapeutics, Inc. (MLYS)

It posted a net loss of $370M. In fiscal 2025 capital spending exceeded operating cash flow by $142.4M. At September 30, 2026 it held $101.3M in cash against $100K of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 4, 2026.

Free, no password. An email when MLYS files with the SEC.

Price
$15.30
-0.19% on the day · November 9, 2026
52-week range $14.91 to $47.65
Market cap
$1.4B

Key facts about Mineralys Therapeutics, Inc.

Net worth
Mineralys Therapeutics, Inc. has a market value (market cap) of $1.4B at the latest share price, and shareholders' equity of $503.8M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Cash flow
In fiscal 2025 operations used $142.4M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 4, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Mineralys Therapeutics, Inc.'s next report is expected around March 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Mineralys Therapeutics, Inc. does

Mineralys Therapeutics, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker MLYS.

Revenue and profit by year

Net income
FY23: -$29.8M -$29.8M FY23FY23: -$71.9M -$71.9M FY23FY24: -$177.8M -$177.8M FY24FY25: -$154.7M -$154.7M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025n/a-$170.6M-$154.7M-$2.29-$142.4M
2024n/a-$192.4M-$177.8M-$3.66-$166.4M
2023n/a-$84.7M-$71.9M-$1.99-$81.2M
2023n/a-$31.5M-$29.8M-$5.77n/a

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around March 11, 2027.

Estimated from its filing rhythm: 52 weeks after its report of March 12, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Latest SEC filings

What Mineralys Therapeutics, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 4, 2026
    Quarterly report 10-Q · period to September 30, 2026Diluted EPS -$0.64 versus -$0.52.
  2. November 4, 2026
  3. October 29, 2026
  4. October 19, 2026
  5. August 11, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$2.85 versus -$0.66.
  6. August 11, 2026
  7. August 6, 2026
  8. June 3, 2026
  9. June 3, 2026
  10. May 22, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 20, 2026. Insider transactions on SEC

Insider trades

What the people running Mineralys Therapeutics, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $5.4M worth of shares in the last 90 days and bought none on the open market. 44% of the selling was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$5.4M
last 90 days
Net sold
197,195
$5.4M
DateInsiderWhatSharesPriceValueFiling
October 19, 2026 Peterson KristineDirector Received as pay 12,400 - - Form 4
October 19, 2026 Coats LonnelDirector Received as pay 12,400 - - Form 4
September 30, 2026 Congleton JonChief Executive Officer, Director Soldpre-planned (10b5-1) 75,000 $25.46 $1.9M Form 4
September 22, 2026 Slingsby Brian TaylorDirector Soldindirect 104,320 $28.81 $3M Form 4
September 21, 2026 Warren EricChief Commercial Officer Exercised options 7,438 $13.24 $98.5K Form 4
September 21, 2026 Warren EricChief Commercial Officer Soldpre-planned (10b5-1) 7,438 $28.12 $209.1K Form 4
September 15, 2026 Karydas DaphneDirector Exercised options 3,000 $12.02 $36.1K Form 4
September 15, 2026 Karydas DaphneDirector Soldpre-planned (10b5-1) 3,000 $28.58 $85.7K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns MLYS

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Catalys Pacific Fund, LP13G, passive with 3 related filers 10.1% 8,002,738 February 13, 2026
RA Capital Management, L.P.13D, may seek influence with 3 related filers 9.9% 7,796,433 September 8, 2025
Srinivas Akkaraju13D, may seek influence with 4 related filers 8.2% 6,346,194 September 8, 2025
Fmr LLC13G, passive with 1 related filers 5.1% 4,461,689 August 6, 2026
TCG Crossover GP II, LLC13G, passive with 2 related filers 5% 2,470,265 November 13, 2024

Latest filings below 5%: Andera Partners 4.2% (August 14, 2025); Adams Street Partners, LLC 2.3% (February 14, 2025); HBM Healthcare Investments (Cayman) Ltd. 4.5% (November 13, 2024).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 226 managers reported a position.

HolderSharesValueChange on quarter
Catalys Pacific, LLC7,903,838$213.2M0
RA Capital Management, L.P.7,692,750$207.6M0
BlackRock, Inc.5,887,038$158.8M+1,405,456
Samsara Biocapital, LLC5,871,018$158.4M0
Fmr LLC4,511,689$121.7M-349,415
State Street Corp4,141,636$111.7M+1,205,696
Deerfield Management Company, L.P.3,958,000$106.8Mnew
Vanguard Capital Management LLC2,756,770$74.4M+302,407
Laurion Capital Management LP2,506,152$67.6M+274,112
Orbimed Advisors LLC2,110,300$56.9M+57,400
Capital World Investors1,997,607$53.9M+1,599,428
Armistice Capital, LLC1,736,000$46.8M+560,000
Troluce Capital Advisors LLC1,728,753$46.6M+1,073,753
Nantahala Capital Management, LLC1,640,962$44.3M+745,481
Franklin Resources Inc1,635,520$44.1M-149,142
Andera Partners1,591,917$42.9M0
Geode Capital Management, LLC1,584,326$42.8M+283,191
SR One Capital Management, LP1,563,966$42.2M0
Bank of America Corp1,505,547$40.6M+405,175
Sphera Funds Management Ltd.1,469,971$39.7M+130,000

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

14 insiders reported holding 14,456,382 shares in total, about $224.4M at the last price.

HolderSharesAs of
Slingsby Brian TaylorDirector, 10% owner 7,805,7187,805,718 held indirectly September 22, 2026
Ra Capital Management, L.P.Director 5,825,5215,825,521 held indirectly March 30, 2026
Congleton JonChief Executive Officer, Director 528,621 September 30, 2026
Ferguson James J. IIIChief Medical Officer 102,400 August 10, 2026
Rodman David MalcomChief Medical Officer 51,384 August 10, 2026
Levy Adam ScottCFO and Secretary 48,538 February 19, 2026
Warren EricChief Commercial Officer 38,400 September 21, 2026
Coats LonnelDirector 12,400 October 19, 2026
Peterson KristineDirector 12,400 October 19, 2026
Gold Alexander MDirector 6,200 February 19, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about MLYS

What does Mineralys Therapeutics, Inc. do?

Mineralys Therapeutics, Inc. is a company in the Health care sector, listed on NASDAQ as MLYS. Its shares trade on NASDAQ under the ticker MLYS.

What is Mineralys Therapeutics, Inc.'s net worth?

Mineralys Therapeutics, Inc. has a market value (market cap) of $1.4B at the latest share price, and shareholders' equity of $503.8M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Mineralys Therapeutics, Inc. profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $370M.

When did Mineralys Therapeutics, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 4, 2026. It covers the period to September 30, 2026.

When is Mineralys Therapeutics, Inc.'s next earnings report?

Mineralys Therapeutics, Inc.'s next report is expected around March 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Mineralys Therapeutics, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.