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Alto Neuroscience, Inc. (ANRO)

It posted a net loss of $84.2M. In fiscal 2025 capital spending exceeded operating cash flow by $51.8M. At June 30, 2026 it held $243.7M in cash against $16.2M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 12, 2026.

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Price
$28.61
+2.91% on the day · November 10, 2026
52-week range $10.80 to $37.48
Market cap
$1.1B

Key facts about Alto Neuroscience, Inc.

Net worth
Alto Neuroscience, Inc. has a market value (market cap) of $1.1B at the latest share price, and shareholders' equity of $219.2M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Cash flow
In fiscal 2025 operations used $51.8M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on August 12, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR
Next earnings report
Alto Neuroscience, Inc.'s next report is expected around November 11, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

What Alto Neuroscience, Inc. does

Alto Neuroscience, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NYSE under the ticker ANRO.

Revenue and profit by year

Net income
FY24: -$36.3M -$36.3M FY24FY24: -$61.4M -$61.4M FY24FY25: -$63.2M -$63.2M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025n/a-$66.4M-$63.2M-$2.19-$51.8M
2024n/a-$68.6M-$61.4M-$2.50-$49.5M
2024n/a-$37.8M-$36.3M-$9.73-$33.9M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around November 11, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 12, 2025. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Latest SEC filings

What Alto Neuroscience, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. October 30, 2026
  2. August 27, 2026
  3. August 14, 2026
  4. August 14, 2026
  5. August 14, 2026
  6. August 12, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$0.65 versus -$0.65.
  7. August 12, 2026
  8. July 27, 2026
  9. July 20, 2026
  10. July 14, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 5, 2026. Insider transactions on SEC

Insider trades

What the people running Alto Neuroscience, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $3.6M worth of shares in the last 90 days and bought none on the open market. All of the selling was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$3.6M
last 90 days
Net sold
134,886
$3.6M
DateInsiderWhatSharesPriceValueFiling
October 2, 2026 Smith Nicholas ConradPRESIDENT AND CFO Exercised options 55,000 $2.32 $127.6K Form 4
September 30, 2026 Smith Nicholas ConradPRESIDENT AND CFO Exercised options 24,056 $2.35 $56.5K Form 4
September 30, 2026 Smith Nicholas ConradPRESIDENT AND CFO Soldpre-planned (10b5-1) 23,170 $25.78 $597.3K Form 4
September 30, 2026 Smith Nicholas ConradPRESIDENT AND CFO Soldpre-planned (10b5-1) 886 $26.87 $23.8K Form 4
September 29, 2026 Smith Nicholas ConradPRESIDENT AND CFO Exercised options 56,455 $2.35 $132.7K Form 4
September 29, 2026 Smith Nicholas ConradPRESIDENT AND CFO Exercised options 54,375 $2.35 $127.8K Form 4
September 29, 2026 Smith Nicholas ConradPRESIDENT AND CFO Soldpre-planned (10b5-1) 110,830 $26.58 $2.9M Form 4
May 14, 2026 Etkin AmitPRESIDENT AND CEO, Director Gave as a gift 400,000 - - Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns ANRO

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Perceptive Advisors LLC13G, passive with 2 related filers 9.99% 4,176,711 August 14, 2026
Commodore Capital LP13G, passive with 3 related filers 9.9% 3,588,180 May 15, 2026
Sirenia Capital Management LP13G, passive with 1 related filers 6.2% 2,219,568 August 14, 2026
EcoR1 Capital, LLC13G, passive with 2 related filers 5.8% 2,232,000 July 20, 2026
Amit Etkin13G, passive 5.4% 1,461,130 November 14, 2024
Vanguard Capital Management13G, passive 5.02% 1,970,108 October 30, 2026

Latest filings below 5%: Vestal Point Capital, LP 2.2% (August 14, 2026); Steven A. Cohen 3.7% (May 15, 2026); Armistice Capital, LLC 4.94% (February 18, 2026); K2 HealthVentures Equity Trust LLC 2.4% (February 17, 2026); RA Capital Management, L.P. 0% (February 14, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 114 managers reported a position.

HolderSharesValueChange on quarter
Alpha Wave Global, LP3,707,757$97.8M0
Commodore Capital LP2,723,196$71.9M0
BlackRock, Inc.2,121,009$56M+1,454,821
Perceptive Advisors LLC1,609,893$42.5M-400,000
Adage Capital Partners GP, L.L.C.1,600,000$42.2M+1,215,000
Vanguard Capital Management LLC1,389,477$36.7M+182,452
Spruce Street Capital LP1,353,047$35.7M+27,837
Vivo Capital, LLC1,208,858$31.9M+173,307
Franklin Resources Inc1,013,307$26.7M-88,567
Armistice Capital, LLC864,000$22.8M-48,000
Affinity Asset Advisors, LLC850,000$22.4M+350,000
Vestal Point Capital, LP785,000$20.7M-1,279,075
State Street Corp685,945$18.1M+486,442
Geode Capital Management, LLC678,199$17.9M+385,300
72 Investment Holdings, LLC667,778$17.6M0
Northern Trust Corp632,701$16.7M+159,298
Millennium Management LLC558,320$14.7M-263,662
Point72 Asset Management, L.P.502,950$13.3M-137
Venrock Adviser, LLC500,000$13.2M0
Integral Health Asset Management, LLC500,000$13.2M0

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

2 insiders reported holding 913,009 shares in total, about $26.1M at the last price.

HolderSharesAs of
Etkin AmitPRESIDENT AND CEO, Director 833,949 May 14, 2026
Smith Nicholas ConradPRESIDENT AND CFO 79,060 October 2, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about ANRO

What does Alto Neuroscience, Inc. do?

Alto Neuroscience, Inc. is a company in the Health care sector, listed on NYSE as ANRO. Its shares trade on NYSE under the ticker ANRO.

What is Alto Neuroscience, Inc.'s net worth?

Alto Neuroscience, Inc. has a market value (market cap) of $1.1B at the latest share price, and shareholders' equity of $219.2M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Alto Neuroscience, Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $84.2M.

When did Alto Neuroscience, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 12, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the passive stake (5% or more) from October 30, 2026.

When is Alto Neuroscience, Inc.'s next earnings report?

Alto Neuroscience, Inc.'s next report is expected around November 11, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Alto Neuroscience, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.