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Lexicon Pharmaceuticals, Inc. (LXRX)

Lexicon Pharmaceuticals, Inc. brought in $41.5M of revenue over the twelve months to June 30, 2026, down 29.0% from a year earlier. It posted a net loss of $61.1M. In fiscal 2025 capital spending exceeded operating cash flow by $67.9M. At June 30, 2026 it held $40.9M in cash against $51.4M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 6, 2026.

Revenue (last 12 months)
$41.5M
-29.0% year on year
Net margin
-147.4%

What Lexicon Pharmaceuticals, Inc. does

Lexicon Pharmaceuticals, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker LXRX.

Revenue and profit by year

Revenue
FY18: $63.2M $63.2M FY18FY19: $322.1M $322.1M FY19FY19: $24M $24M FY19FY21: $298K $298K FY21FY22: $139K $139K FY22FY23: $1.2M $1.2M FY23FY24: $31.1M $31.1M FY24FY25: $49.8M $49.8M FY25
Net income
FY18: -$120.5M -$120.5M FY18FY19: $130.1M $130.1M FY19FY19: -$58.6M -$58.6M FY19FY21: -$87.8M -$87.8M FY21FY22: -$101.9M -$101.9M FY22FY23: -$177.1M -$177.1M FY23FY24: -$200.4M -$200.4M FY24FY25: -$50.3M -$50.3M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$49.8M-$48.9M-$50.3M-$0.14-$67.9M
2024$31.1M-$197.1M-$200.4M-$0.63-$179.8M
2023$1.2M-$171.8M-$177.1M-$0.80-$162.4M
2022$139K-$100.8M-$101.9M-$0.62-$90.2M
2021$298K-$87.1M-$87.8M-$0.60-$88.2M
2019$24M-$47.8M-$58.6M-$0.53-$143.1M

Latest SEC filings

What Lexicon Pharmaceuticals, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. August 6, 2026
  2. August 6, 2026
  3. August 6, 2026
    Quarterly report 10-Q · period to June 30, 2026
  4. August 6, 2026
  5. August 6, 2026
  6. May 8, 2026
  7. May 7, 2026
    Quarterly report 10-Q · period to March 31, 2026
  8. May 7, 2026
  9. May 6, 2026
  10. April 30, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on June 4, 2026. Insider transactions on SEC

All filings on SEC EDGAR

Questions about LXRX

What does Lexicon Pharmaceuticals, Inc. do?

Lexicon Pharmaceuticals, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker LXRX.

Is Lexicon Pharmaceuticals, Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $61.1M on revenue of $41.5M.

How much revenue does Lexicon Pharmaceuticals, Inc. make?

Over the twelve months to June 30, 2026 Lexicon Pharmaceuticals, Inc. reported revenue of $41.5M. That is 29.0% less than a year earlier.

When did Lexicon Pharmaceuticals, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 6, 2026. It covers the period to June 30, 2026.

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Where the numbers come from

Financial figures are the values Lexicon Pharmaceuticals, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.