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MBX Biosciences, Inc. (MBX)

It posted a net loss of $145.1M. In fiscal 2025 capital spending exceeded operating cash flow by $81.9M. At September 30, 2026 it held $161.7M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 9, 2026.

Free, no password. An email when MBX files with the SEC.

Price
$54.06
+5.28% on the day · November 9, 2026
52-week range $23.07 to $72.64
Market cap
$2.6B

Key facts about MBX Biosciences, Inc.

Net worth
MBX Biosciences, Inc. has a market value (market cap) of $2.6B at the latest share price, and shareholders' equity of $472.9M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Cash flow
In fiscal 2025 operations used $79.9M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 9, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
MBX Biosciences, Inc.'s next report is expected around January 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What MBX Biosciences, Inc. does

MBX Biosciences, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker MBX.

Revenue and profit by year

Net income
FY24: -$32.6M -$32.6M FY24FY24: -$61.9M -$61.9M FY24FY25: -$87M -$87M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025n/a-$98.1M-$87M-$2.38-$81.9M
2024n/a-$68.2M-$61.9M-$5.82-$55.6M
2024n/a-$35.3M-$32.6M-$31.96-$32.1M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around January 11, 2027.

Estimated from its filing rhythm: 52 weeks after its report of January 12, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Latest SEC filings

What MBX Biosciences, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 9, 2026
    Quarterly report 10-Q · period to September 30, 2026Diluted EPS -$1.29 versus -$0.63.
  2. November 9, 2026
  3. November 5, 2026
  4. October 22, 2026
  5. August 27, 2026
  6. August 14, 2026
  7. August 10, 2026
  8. August 10, 2026
  9. August 6, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$0.78 versus -$0.58.
  10. August 6, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on November 5, 2026. Insider transactions on SEC

Insider trades

What the people running MBX Biosciences, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $20.1K worth of shares in the last 90 days and bought none on the open market.

Bought (open market)
$0
last 90 days
Sold
$20.1K
last 90 days
Net sold
373
$20.1K
DateInsiderWhatSharesPriceValueFiling
November 4, 2026 Azoulay SalomonChief Medical Officer Sold 373 $53.96 $20.1K Form 4
August 4, 2026 Azoulay SalomonChief Medical Officer Sold 370 $65.77 $24.3K Form 4
August 3, 2026 Hoerter Steven L.President and CEO, Director Received as pay 71,000 - - Form 4
August 3, 2026 Smither John WChief Financial Officer Received as pay 28,000 - - Form 4
May 8, 2026 Azoulay SalomonChief Medical Officer Exercised options 55,000 $10.46 $575.3K Form 4
May 8, 2026 Azoulay SalomonChief Medical Officer Soldpre-planned (10b5-1) 55,000 $38.38 $2.1M Form 4
May 8, 2026 Azoulay SalomonChief Medical Officer Exercised options 15,003 $16.00 $240K Form 4
May 8, 2026 Azoulay SalomonChief Medical Officer Soldpre-planned (10b5-1) 15,003 $38.30 $574.6K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns MBX

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
James N. Topper13D, may seek influence with 16 related filers 18.8% 5,985,347 September 23, 2024
Patrick J. Heron13D, may seek influence with 10 related filers 11.7% 5,243,421 August 10, 2026
New Enterprise Associates 17, L.P.13D, may seek influence with 11 related filers 11.4% 3,614,486 September 23, 2024
Fmr LLC13G, passive with 1 related filers 11.2% 5,322,885 July 8, 2026
Wellington Management Group LLP13G, passive with 3 related filers 10.5% 4,977,523 July 8, 2026
Edward T. Mathers13D, may seek influence with 11 related filers 8.1% 3,619,474 November 10, 2025
Norwest Venture Partners XVI, LP13D, may seek influence with 5 related filers 6.4% 2,136,335 September 23, 2024
Orbimed Advisors LLC13D, may seek influence with 2 related filers 6.4% 3,074,853 August 10, 2026
Paradigm BioCapital Advisors LP13G, passive with 3 related filers 5.2% 2,493,015 June 24, 2026

Latest filings below 5%: Deep Track Capital, LP 3.64% (August 14, 2026); P. Kent Hawryluk 4.3% (November 14, 2025); Wellington Biomedical Innovation Master Investors (Cayman) II, L.P. 4.5% (November 12, 2025); Tiba Aynechi 4.8% (September 30, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 173 managers reported a position.

HolderSharesValueChange on quarter
Frazier Life Sciences Management, L.P.6,652,013$367.2M0
Fmr LLC5,322,885$293.8M+2,386,201
Wellington Management Group Llp4,977,523$274.8M+1,785,699
NEA Management Company, LLC3,614,486$199.5M0
Orbimed Advisors LLC3,428,736$189.3M-209,151
BlackRock, Inc.3,323,672$183.5M+382,266
Paradigm Biocapital Advisors LP2,508,015$138.4Mnew
Nvp Associates, LLC2,136,335$117.9M0
Deep Track Capital, LP1,732,569$95.6M-1,025,000
Polar Capital Holdings Plc1,608,514$88.8M-13,672
Vanguard Capital Management LLC1,477,388$81.6M-204
Aaron Wealth Advisors LLC1,167,799$64.5M-377
Driehaus Capital Management LLC1,056,579$58.3M+38,367
Kynam Capital Management, LP934,799$51.6M0
Woodline Partners LP900,092$49.7M+29
Eventide Asset Management, LLC873,492$48.2M-16,508
State Street Corp864,466$47.7M+77,258
Parkman Healthcare Partners LLC800,173$44.2M+136
Geode Capital Management, LLC773,072$42.7M+102,687
Braidwell LP710,880$39.2M-781,587

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

5 insiders reported holding 1,354,408 shares in total, about $73.2M at the last price.

HolderSharesAs of
Hawryluk P. KentPresident & CEO, Director 1,214,444486,777 held indirectly May 6, 2026
Hoerter Steven L.President and CEO, Director 82,938 August 3, 2026
Smither John WChief Financial Officer 28,000 August 3, 2026
Bartram RichardChief Financial Officer 15,000 February 2, 2026
Azoulay SalomonChief Medical Officer 14,026 November 4, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about MBX

What does MBX Biosciences, Inc. do?

MBX Biosciences, Inc. is a company in the Health care sector, listed on NASDAQ as MBX. Its shares trade on NASDAQ under the ticker MBX.

What is MBX Biosciences, Inc.'s net worth?

MBX Biosciences, Inc. has a market value (market cap) of $2.6B at the latest share price, and shareholders' equity of $472.9M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is MBX Biosciences, Inc. profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $145.1M.

When did MBX Biosciences, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 9, 2026. It covers the period to September 30, 2026.

When is MBX Biosciences, Inc.'s next earnings report?

MBX Biosciences, Inc.'s next report is expected around January 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values MBX Biosciences, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.