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NASDAQ · Health care

Trevi Therapeutics, Inc. (TRVI)

It posted a net loss of $60.8M. In fiscal 2025 capital spending exceeded operating cash flow by $42.1M. At September 30, 2026 it held $27.8M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 9, 2026.

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Price
$14.93
-2.51% on the day · November 10, 2026
52-week range $9.82 to $20.22
Market cap
$2.1B

Key facts about Trevi Therapeutics, Inc.

Net worth
Trevi Therapeutics, Inc. has a market value (market cap) of $2.1B at the latest share price, and shareholders' equity of $302.8M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Cash flow
In fiscal 2025 operations used $42.1M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 9, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Trevi Therapeutics, Inc.'s next report is expected around March 16, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Trevi Therapeutics, Inc. does

Trevi Therapeutics, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker TRVI.

Revenue and profit by year

Net income
FY19: -$20.5M -$20.5M FY19FY19: -$26.1M -$26.1M FY19FY20: -$32.8M -$32.8M FY20FY21: -$33.9M -$33.9M FY21FY22: -$29.2M -$29.2M FY22FY23: -$29.1M -$29.1M FY23FY24: -$47.9M -$47.9M FY24FY25: -$42.8M -$42.8M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025n/a-$49.3M-$42.8M-$0.32-$42.1M
2024n/a-$51.5M-$47.9M-$0.47-$38.3M
2023n/a-$33.9M-$29.1M-$0.29-$31.8M
2022n/a-$29.9M-$29.2M-$0.45-$28.3M
2021n/a-$32.5M-$33.9M-$1.49n/a
2020n/a-$32.5M-$32.8M-$1.81-$29M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around March 16, 2027.

Estimated from its filing rhythm: 52 weeks after its report of March 17, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Latest SEC filings

What Trevi Therapeutics, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 9, 2026
    Quarterly report 10-Q · period to September 30, 2026Diluted EPS -$0.13 versus -$0.08.
  2. November 9, 2026
  3. October 27, 2026
  4. August 6, 2026
  5. August 6, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$0.11 versus -$0.09.
  6. August 6, 2026
  7. August 6, 2026
  8. June 4, 2026
  9. May 7, 2026
  10. May 6, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on September 17, 2026. Insider transactions on SEC

Insider trades

What the people running Trevi Therapeutics, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $595.8K worth of shares in the last 90 days and bought none on the open market. All of the selling was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$595.8K
last 90 days
Net sold
39,473
$595.8K
DateInsiderWhatSharesPriceValueFiling
September 15, 2026 Heffernan Michael ThomasDirector Exercised options 18,421 $3.04 $56K Form 4
September 15, 2026 Heffernan Michael ThomasDirector Soldpre-planned (10b5-1) 18,321 $15.09 $276.5K Form 4
September 15, 2026 Heffernan Michael ThomasDirector Soldpre-planned (10b5-1) 100 $15.88 $1.6K Form 4
September 15, 2026 Heffernan Michael ThomasDirector Exercised options 21,052 $3.33 $70.1K Form 4
September 15, 2026 Heffernan Michael ThomasDirector Soldpre-planned (10b5-1) 20,952 $15.09 $316.2K Form 4
September 15, 2026 Heffernan Michael ThomasDirector Soldpre-planned (10b5-1) 100 $15.88 $1.6K Form 4
December 2, 2025 Galletta ChristopherSee Remarks Exercised options 4,225 $0.51 $2.2K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns TRVI

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
New Enterprise Associates 16, L.P.13D, may seek influence with 12 related filers 10.5% 15,074,080 May 7, 2026
Fmr LLC13G, passive with 1 related filers 8.8% 12,562,839 August 6, 2026
Frazier Life Sciences Public Fund, L.P.13G, passive with 13 related filers 7% 8,508,021 November 14, 2025
BlackRock, Inc.13G, passive 6.9% 9,779,593 October 27, 2026

Latest filings below 5%: The Vanguard Group 0% (March 27, 2026); Rubric Capital Management LP 2.94% (February 13, 2026); Viking Global Investors LP 4.2% (November 14, 2025); Venrock Healthcare Capital Partners II, L.P. 1.4% (February 14, 2025); Rosalind Advisors, Inc. 1.2% (February 13, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 218 managers reported a position.

HolderSharesValueChange on quarter
NEA Management Company, LLC13,222,228$246.6M0
Fmr LLC12,562,839$234.3M+4,524,778
BlackRock, Inc.11,155,026$208M+914,840
Frazier Life Sciences Management, L.P.9,939,447$185.4M-100
Wellington Management Group Llp5,684,592$106M+495,504
Vanguard Capital Management LLC5,530,675$103.1M+552,108
Vivo Capital, LLC5,094,668$95M0
Woodline Partners LP4,081,333$76.1M+3,080,551
Vestal Point Capital, LP3,100,000$57.8M+933,496
Mpm Bioimpact LLC3,073,577$57.3M-224,853
Frontier Capital Management Co LLC3,070,740$57.3M+1,076,448
Assenagon Asset Management S.A.3,050,628$56.9Mnew
State Street Corp3,027,315$56.5M+362,002
Geode Capital Management, LLC2,928,068$54.6M+149,837
Marshall Wace, Llp2,674,137$49.9M-1,291,882
Eventide Asset Management, LLC2,660,000$49.6M+37,694
Rubric Capital Management LP2,504,513$46.7M-1,207,860
Artia Global Partners LP2,210,852$41.2M+197,250
Acorn Capital Advisors, LLC2,144,844$40M0
First Light Asset Management, LLC2,097,215$39.1Mnew

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

2 insiders reported holding 32,446 shares in total, about $484.4K at the last price.

HolderSharesAs of
Galletta ChristopherSee Remarks 26,095 December 2, 2025
Heffernan Michael ThomasDirector 6,351 September 15, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about TRVI

What does Trevi Therapeutics, Inc. do?

Trevi Therapeutics, Inc. is a company in the Health care sector, listed on NASDAQ as TRVI. Its shares trade on NASDAQ under the ticker TRVI.

What is Trevi Therapeutics, Inc.'s net worth?

Trevi Therapeutics, Inc. has a market value (market cap) of $2.1B at the latest share price, and shareholders' equity of $302.8M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Trevi Therapeutics, Inc. profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $60.8M.

When did Trevi Therapeutics, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 9, 2026. It covers the period to September 30, 2026.

When is Trevi Therapeutics, Inc.'s next earnings report?

Trevi Therapeutics, Inc.'s next report is expected around March 16, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Trevi Therapeutics, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.