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NASDAQ · Health care

Opus Genetics, Inc. (IRD)

Opus Genetics, Inc. brought in $9.9M of revenue over the twelve months to June 30, 2026, down 36.1% from a year earlier. It posted a net loss of $107.6M. At June 30, 2026 it held $88.8M in cash against $35.3M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 6, 2026.

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Price
$4.20
+0.48% on the day · November 9, 2026
52-week range $1.70 to $7.07
Market cap
$349.4M
Revenue (last 12 months)
$9.9M
-36.1% year on year
Net margin
-1,091.8%

Key facts about Opus Genetics, Inc.

Net worth
Opus Genetics, Inc. has a market value (market cap) of $349.4M at the latest share price, and shareholders' equity of -$13M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $14.2M (+29.1% year on year), with a net loss of $49.6M. Over the 12 months to June 30, 2026: revenue $9.9M, net loss $107.6M.
Cash flow
In fiscal 2025 operations used $35.3M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on August 6, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR
Next earnings report
Opus Genetics, Inc.'s next report is expected around November 11, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

What Opus Genetics, Inc. does

Opus Genetics, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker IRD.

Revenue and profit by year

Revenue
FY19: $3M $3M FY19FY20: $0 $0 FY20FY21: $589K $589K FY21FY22: $39.9M $39.9M FY22FY23: $19M $19M FY23FY24: $11M $11M FY24FY25: $14.2M $14.2M FY25
Net income
FY18: -$14.4M -$14.4M FY18FY19: -$6.2M -$6.2M FY19FY20: -$24.6M -$24.6M FY20FY21: -$56.7M -$56.7M FY21FY22: $17.9M $17.9M FY22FY23: -$10M -$10M FY23FY24: -$57.5M -$57.5M FY24FY25: -$49.6M -$49.6M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$14.2M-$38.6M-$49.6M-$0.80n/a
2024$11M-$62.1M-$57.5M-$2.15n/a
2023$19M-$10.6M-$10M-$0.46n/a
2022$39.9M$18.2M$17.9M$0.87n/a
2021$589K-$22.7M-$56.7M-$3.82n/a
2020$0-$20M-$24.6M-$5.28-$6.8M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around November 11, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 12, 2025. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where IRD ranks in Health care

Revenue$14.2M
#497 of 751 in Health care · Bottom 34%
Revenue growth+29.1%
#138 of 532 in Health care · Top 26%
Net margin-349.3%
#507 of 544 in Health care · Bottom 7%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Opus Genetics, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. October 27, 2026
  2. October 21, 2026
  3. October 15, 2026
  4. September 11, 2026
  5. September 9, 2026
  6. August 14, 2026
  7. August 14, 2026
  8. August 14, 2026
  9. August 7, 2026
  10. August 6, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue fell 74% to $755K versus the same quarter last year; diluted EPS -$0.14 versus -$0.12.

Recent insider filings (Forms 3, 4 and 144): 10, the latest on November 5, 2026. Insider transactions on SEC

Insider trades

What the people running Opus Genetics, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $3.2M worth of shares in the last 90 days and bought none on the open market. 6% of the selling was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$3.2M
last 90 days
Net sold
673,805
$3.2M
DateInsiderWhatSharesPriceValueFiling
November 3, 2026 Magrath GeorgeChief Executive Officer, Director Sold 28,258 $3.90 $110.2K Form 4
October 23, 2026 Magrath GeorgeChief Executive Officer, Director Sold 9,591 $3.59 $34.4K Form 4
October 23, 2026 Gagnon Robert E.Chief Financial Officer Soldpre-planned (10b5-1) 14,000 $3.55 $49.6K Form 4
October 23, 2026 Yerxa Benjamin RPresident, Director Sold 7,669 $3.55 $27.2K Form 4
October 23, 2026 Yerxa Benjamin RPresident, Director Sold 25,520 $3.53 $90.1K Form 4
October 23, 2026 Schachle Joseph KChief Operating Officer Sold 4,767 $3.57 $17K Form 4
September 30, 2026 Foundation Fighting Blindness Retinal Degeneration FundDirector Sold 556,000 $4.96 $2.8M Form 4
September 9, 2026 Magrath GeorgeChief Executive Officer, Director Exercised options 392,157 $1.15 $451K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns IRD

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Perceptive Advisors LLC13G, passive with 2 related filers 9.99% 9,233,710 August 14, 2026
Adage Capital Management, L.P.13G, passive with 2 related filers 8.47% 6,029,775 May 13, 2026
Caligan Partners LP13G, passive with 1 related filers 7.3% 6,077,084 August 14, 2026
Balyasny Asset Management L.P.13G, passive with 4 related filers 6.64% 5,480,210 August 14, 2026
Nantahala Capital Management, LLC13G, passive with 2 related filers 6.51% 4,839,225 May 15, 2026
BlackRock, Inc.13G, passive 6.1% 5,044,847 October 27, 2026

Latest filings below 5%: Foundation Fighting Blindness Retinal Degeneration Fund 4.66% (May 20, 2026); Aaron G.L. Fletcher 4.53% (May 13, 2026).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 103 managers reported a position.

HolderSharesValueChange on quarter
Nantahala Capital Management, LLC6,122,718$25.2M+4,441,388
Caligan Partners LP6,077,084$25M+2,056
Adage Capital Partners GP, L.L.C.6,029,775$24.8M0
BIOS Capital Management, LP3,683,429$15.1M0
BlackRock, Inc.3,116,487$12.8M+2,968,747
Balyasny Asset Management L.P.3,087,866$12.7M+369,837
Vanguard Capital Management LLC2,958,683$12.2M+508,696
Boxer Capital Management, LLC2,815,000$11.6M+565,000
Trails Edge Capital Partners, LP2,743,658$11.3M+2,243,658
Millennium Management LLC2,302,101$9.5M-328,331
Great Point Partners LLC1,970,187$8.1M+1,645,847
Marshall Wace, Llp1,945,609$8M-367,771
ADAR1 Capital Management, LLC1,783,781$7.3M-65,223
Goldman Sachs Group Inc1,527,229$6.3M+1,200,420
Woodline Partners LP1,434,713$5.9M+80,683
Geode Capital Management, LLC1,367,712$5.6M+829,365
Boothbay Fund Management, LLC1,189,515$4.9M+402
Opaleye Management Inc.1,125,000$4.6M+5,000
SummitTX Capital, L.P.1,007,351$4.1Mnew
State Street Corp790,136$3.2M+590,183

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

14 insiders reported holding 11,940,246 shares in total, about $50.1M at the last price.

HolderSharesAs of
Foundation Fighting Blindness Retinal Degeneration FundDirector 3,236,171 September 30, 2026
Gallagher CamDirector 2,883,11183,000 held indirectly September 8, 2026
Magrath GeorgeChief Executive Officer, Director 2,010,636 November 3, 2026
Yerxa Benjamin RPresident, Director 670,917 October 23, 2026
Gagnon Robert E.Chief Financial Officer 542,375 October 23, 2026
Jayagopal AshwathChief Scientific & Dev. Ofc. 509,233 April 23, 2026
Rodgers Richard JDirector 343,022 April 20, 2026
Ainsworth SeanDirector 321,692 April 20, 2026
Manuso James S JDirector 317,318 April 20, 2026
Schachle Joseph KChief Operating Officer 286,673 October 23, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about IRD

What does Opus Genetics, Inc. do?

Opus Genetics, Inc. is a company in the Health care sector, listed on NASDAQ as IRD. Its shares trade on NASDAQ under the ticker IRD.

What is Opus Genetics, Inc.'s net worth?

Opus Genetics, Inc. has a market value (market cap) of $349.4M at the latest share price, and shareholders' equity of -$13M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Opus Genetics, Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $107.6M on revenue of $9.9M.

How much revenue does Opus Genetics, Inc. make?

Over the twelve months to June 30, 2026 Opus Genetics, Inc. reported revenue of $9.9M. That is 36.1% less than a year earlier.

When did Opus Genetics, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 6, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the insider trade from November 5, 2026.

When is Opus Genetics, Inc.'s next earnings report?

Opus Genetics, Inc.'s next report is expected around November 11, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Opus Genetics, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.