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NASDAQ · Health care

Zentalis Pharmaceuticals, Inc. (ZNTL)

It posted a net loss of $141.7M. In fiscal 2025 capital spending exceeded operating cash flow by $125.2M. At September 30, 2026 it held $24M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 9, 2026.

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Price
$1.80
+3.45% on the day · November 10, 2026
52-week range $1.25 to $6.95
Market cap
$170.4M

Key facts about Zentalis Pharmaceuticals, Inc.

Net worth
Zentalis Pharmaceuticals, Inc. has a market value (market cap) of $170.4M at the latest share price, and shareholders' equity of $204.9M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $0 (-100.0% year on year), with a net loss of $137.1M.
Cash flow
In fiscal 2025 operations used $125.2M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 9, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Zentalis Pharmaceuticals, Inc.'s next report is expected around March 25, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Zentalis Pharmaceuticals, Inc. does

Zentalis Pharmaceuticals, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker ZNTL.

Revenue and profit by year

Revenue
FY22: $0 $0 FY22FY23: $0 $0 FY23FY24: $67.4M $67.4M FY24FY25: $0 $0 FY25
Net income
FY20: -$45.7M -$45.7M FY20FY20: -$117.8M -$117.8M FY20FY21: -$158.7M -$158.7M FY21FY22: -$236.8M -$236.8M FY22FY23: -$292.2M -$292.2M FY23FY24: -$165.8M -$165.8M FY24FY25: -$137.1M -$137.1M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$0-$152.8M-$137.1M-$1.91-$125.2M
2024$67.4M-$191.2M-$165.8M-$2.33-$171.1M
2023$0-$299.5M-$292.2M-$4.47-$208.4M
2022$0-$227.3M-$236.8M-$4.48-$166.3M
2021n/a-$216.5M-$158.7M-$3.72-$160.2M
2020n/a-$118.8M-$117.8M-$4.19-$87.6M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around March 25, 2027.

Estimated from its filing rhythm: 52 weeks after its report of March 26, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Latest SEC filings

What Zentalis Pharmaceuticals, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 9, 2026
    Quarterly report 10-Q · period to September 30, 2026Diluted EPS -$0.34 versus -$0.37.
  2. November 9, 2026
  3. October 27, 2026
  4. August 19, 2026
  5. August 14, 2026
  6. August 13, 2026
  7. August 6, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$0.59 versus -$0.37.
  8. August 6, 2026
  9. July 30, 2026
  10. June 18, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 1, 2026. Insider transactions on SEC

Insider trades

What the people running Zentalis Pharmaceuticals, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders bought $15.2M worth of shares on the open market in the last 90 days and sold none.

Bought (open market)
$15.2M
last 90 days
Sold
$0
last 90 days
Net bought
4,335,000
$15.2M
DateInsiderWhatSharesPriceValueFiling
September 30, 2026 Bruns IngmarChief Medical Officer Received as pay 9,727 $2.18 $21.2K Form 4
August 14, 2026 Walters Group10% owner Bought 4,335,000 $3.50 $15.2M Form 4
June 16, 2026 Myers Scott DunsethDirector Received as pay 57,100 - - Form 4
June 16, 2026 Walker Luke NathanielDirector Received as pay 57,100 - - Form 4
June 16, 2026 Johnson David MichaelDirector Received as pay 57,100 - - Form 4
June 16, 2026 Skvarka JanDirector Received as pay 57,100 - - Form 4
June 16, 2026 Kariuki EnochDirector Received as pay 57,100 - - Form 4
May 26, 2026 Campbell ShannonDirector Received as pay 114,200 - - Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns ZNTL

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Walters William T13G, passive with 2 related filers 18.8% 17,844,973 August 19, 2026
Andrew J. Schwab13G, passive with 6 related filers 6.4% 4,838,571 December 30, 2025
Squadron Master Fund LP13G, passive with 3 related filers 5.1% 3,676,900 March 3, 2026

Latest filings below 5%: BlackRock, Inc. 4.1% (October 27, 2026); Matrix Capital Management Company, LP 0% (January 2, 2026); Millennium Management LLC 1.3% (October 14, 2025); Eventide Asset Management, LLC 0% (May 14, 2025); The Vanguard Group 4.59% (January 31, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 114 managers reported a position.

HolderSharesValueChange on quarter
5AM Venture Management, LLC3,947,913$19.1M0
BlackRock, Inc.3,753,525$18.2M+2,483,688
Squadron Capital Management LLC3,700,000$17.9M+69,000
Two Sigma Investments, LP3,024,936$14.7M+68,410
Vanguard Capital Management LLC2,835,669$13.8M+524,962
Citadel Advisors LLC2,298,403$11.1M+566,320
Renaissance Technologies LLC1,609,078$7.8M-329,067
Opaleye Management Inc.1,412,656$6.9M0
Orbimed Advisors LLC1,390,576$6.7Mnew
Decheng Capital LLC1,323,327$6.4M0
Geode Capital Management, LLC1,284,117$6.2M+663,081
Bank of America Corp1,114,650$5.4M-17,644
Ishara Investments LP1,025,000$5M-205,000
Primecap Management Co957,420$4.6M0
Soleus Capital Management, L.P.950,000$4.6Mnew
State Street Corp887,416$4.3M+637,726
Vanguard Portfolio Management LLC808,548$3.9M+447,948
Pfizer Inc953,834$3.9M0
Connor, Clark & Lunn Investment Management Ltd.758,033$3.7M-33,968
Millennium Management LLC664,281$3.2M-625,541

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

11 insiders reported holding 26,051,363 shares in total, about $46.9M at the last price.

HolderSharesAs of
Walters Group10% owner 17,844,973 August 14, 2026
Matrix Capital Management Company, LP10% owner 6,459,9736,459,973 held indirectly December 15, 2025
Myers Scott DunsethDirector 395,895 June 16, 2026
Johnson David MichaelDirector 307,521 June 16, 2026
Skvarka JanDirector 264,254 June 16, 2026
Walker Luke NathanielDirector 201,384 June 16, 2026
Kariuki EnochDirector 194,465 June 16, 2026
Vultaggio VincentPAO and PFO 146,506 February 10, 2026
Campbell ShannonDirector 114,200 May 26, 2026
Eastland Julia MarieCEO & President, Director 79,133 February 9, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about ZNTL

What does Zentalis Pharmaceuticals, Inc. do?

Zentalis Pharmaceuticals, Inc. is a company in the Health care sector, listed on NASDAQ as ZNTL. Its shares trade on NASDAQ under the ticker ZNTL.

What is Zentalis Pharmaceuticals, Inc.'s net worth?

Zentalis Pharmaceuticals, Inc. has a market value (market cap) of $170.4M at the latest share price, and shareholders' equity of $204.9M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Zentalis Pharmaceuticals, Inc. profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $141.7M.

When did Zentalis Pharmaceuticals, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 9, 2026. It covers the period to September 30, 2026.

When is Zentalis Pharmaceuticals, Inc.'s next earnings report?

Zentalis Pharmaceuticals, Inc.'s next report is expected around March 25, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Zentalis Pharmaceuticals, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.