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NASDAQ · Health care

Castle Biosciences Inc (CSTL)

Castle Biosciences Inc brought in $357.3M of revenue over the twelve months to June 30, 2026, up 3.2% from a year earlier. It posted a net loss of $19.4M. Operating cash flow minus capital spending left $28.3M of free cash flow in fiscal 2025. At June 30, 2026 it held $62.1M in cash against $10.1M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on July 30, 2026.

Price
$35.81
+1.76% on the day · September 25, 2026
52-week range $17.72 to $44.28
Market cap
$1.1B
Revenue (last 12 months)
$357.3M
+3.2% year on year
Net margin
-5.4%

What Castle Biosciences Inc does

Castle Biosciences Inc is registered with the SEC under industry code SIC 8071 (Services-Medical Laboratories). Its shares trade on NASDAQ under the ticker CSTL.

Revenue and profit by year

Revenue
FY19: $22.8M $22.8M FY19FY19: $51.9M $51.9M FY19FY20: $62.6M $62.6M FY20FY21: $94.1M $94.1M FY21FY22: $137M $137M FY22FY23: $219.8M $219.8M FY23FY24: $332.1M $332.1M FY24FY25: $344.2M $344.2M FY25
Net income
FY19: -$6.4M -$6.4M FY19FY19: $5.3M $5.3M FY19FY20: -$10.3M -$10.3M FY20FY21: -$31.3M -$31.3M FY21FY22: -$67.1M -$67.1M FY22FY23: -$57.5M -$57.5M FY23FY24: $18.2M $18.2M FY24FY25: -$24.2M -$24.2M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$344.2M-$42.8M-$24.2M-$0.83$28.3M
2024$332.1M$8.7M$18.2M$0.62$36.5M
2023$219.8M-$68M-$57.5M-$2.14-$19.2M
2022$137M-$72.9M-$67.1M-$2.58-$47.3M
2021$94.1M-$40.1M-$31.3M-$1.24-$22.5M
2020$62.6M-$6.5M-$10.3M-$0.54$5.1M
Next report expected around November 2, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 3, 2025. Not a date the company has announced. See the report calendar

Where CSTL ranks in Health care

Revenue$344.2M
#214 of 523 in Health care · Top 41%
Revenue growth+3.7%
#315 of 437 in Health care · Bottom 28%
Net margin-7.0%
#232 of 447 in Health care · Bottom 48%
Free cash flow margin8.2%
#135 of 408 in Health care · Top 33%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Castle Biosciences Inc has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. July 30, 2026
    Quarterly report 10-Q · period to June 30, 2026
  2. July 30, 2026
  3. May 29, 2026
  4. May 15, 2026
  5. May 15, 2026
  6. May 6, 2026
    Quarterly report 10-Q · period to March 31, 2026
  7. May 6, 2026
  8. April 8, 2026
  9. April 8, 2026
  10. April 8, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on September 23, 2026. Insider transactions on SEC

What is CSTL worth? A DCF from its reported cash flow

Insider trades

What the people running Castle Biosciences Inc did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $3.2M worth of shares in the last 90 days and bought none on the open market. Most of the selling (74%) was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$3.2M
last 90 days
Net sold
93,708
$3.2M
DateInsiderWhatSharesPriceValueFiling
September 21, 2026 Maetzold Derek JPres. & Chief Exec. Officer, Director Exercised options 8,580 $2.39 $20.5K Form 4
September 21, 2026 Maetzold Derek JPres. & Chief Exec. Officer, Director Soldpre-planned (10b5-1) 8,580 $35.33 $303.2K Form 4
September 21, 2026 Maetzold Derek JPres. & Chief Exec. Officer, Director Soldpre-planned (10b5-1), indirect 3,198 $35.33 $113K Form 4
September 21, 2026 Maetzold Derek JPres. & Chief Exec. Officer, Director Soldpre-planned (10b5-1), indirect 2,718 $35.33 $96K Form 4
September 15, 2026 Juvenal Tobin WChief Commercial Officer Soldpre-planned (10b5-1) 3,294 $35.14 $115.8K Form 4
September 14, 2026 Juvenal Tobin WChief Commercial Officer Soldpre-planned (10b5-1) 3,306 $32.32 $106.9K Form 4
September 11, 2026 Maetzold Derek JPres. & Chief Exec. Officer, Director Exercised options 8,584 $2.39 $20.5K Form 4
September 11, 2026 Maetzold Derek JPres. & Chief Exec. Officer, Director Soldpre-planned (10b5-1) 8,361 $32.00 $267.6K Form 4
September 11, 2026 Maetzold Derek JPres. & Chief Exec. Officer, Director Soldpre-planned (10b5-1), indirect 3,124 $32.00 $100K Form 4
September 11, 2026 Maetzold Derek JPres. & Chief Exec. Officer, Director Soldpre-planned (10b5-1), indirect 2,656 $32.00 $85K Form 4
September 11, 2026 Maetzold Derek JPres. & Chief Exec. Officer, Director Soldpre-planned (10b5-1) 223 $32.78 $7.3K Form 4
September 11, 2026 Maetzold Derek JPres. & Chief Exec. Officer, Director Soldpre-planned (10b5-1), indirect 83 $32.78 $2.7K Form 4
September 11, 2026 Maetzold Derek JPres. & Chief Exec. Officer, Director Soldpre-planned (10b5-1), indirect 71 $32.78 $2.3K Form 4
September 1, 2026 Oelschlager Kristen MChief Operating Officer Exercised options 4,152 $3.38 $14K Form 4
September 1, 2026 Oelschlager Kristen MChief Operating Officer Soldpre-planned (10b5-1) 3,952 $33.36 $131.8K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

All filings on SEC EDGAR

Questions about CSTL

What does Castle Biosciences Inc do?

Castle Biosciences Inc is registered with the SEC under industry code SIC 8071 (Services-Medical Laboratories). Its shares trade on NASDAQ under the ticker CSTL.

Is Castle Biosciences Inc profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $19.4M on revenue of $357.3M.

How much revenue does Castle Biosciences Inc make?

Over the twelve months to June 30, 2026 Castle Biosciences Inc reported revenue of $357.3M. That is 3.2% more than a year earlier.

When did Castle Biosciences Inc last report?

Its most recent periodic report is the quarterly report (10-Q) filed on July 30, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the insider trade from September 23, 2026.

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Where the numbers come from

Financial figures are the values Castle Biosciences Inc tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.