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Financial statements

Crinetics Pharmaceuticals, Inc. financial statements

Income statement, balance sheet and cash flow statement for the last 10 fiscal years, taken from the XBRL data Crinetics Pharmaceuticals, Inc. files with the SEC in its annual reports.

In USD millions, except per-share amounts. Outflows in the cash flow statement are negative.

Income statement

FY2016FY2018FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue0.592.052.431.190.071.084.744.011.047.7
Cost of revenue001.08
Gross profit4.011.046.62
Research and development5.19.2324.541.55784.3130169240332
Selling, general and administrative58.199.7191
General and administrative1.531.946.6613.51824.542.458.199.7
Operating expenses6.6311.231.15575109173227340
Operating income-6.04-9.13-28.7-53.8-75-108-168-223-339-517
Interest expense0.010.01
Interest income0.040.031.753.460.990.164.3213.441.452
Other non-operating income0.03-0.031.63.411.140.064.9713.340.951.6
Pre-tax income-6.02-9.16-27.1-50.4-73.8-108-164-215-298-465
Income tax0000000000.18
Net income-6.02-9.16-27.1-50.4-73.8-108-164-215-298-465
EBITDA-5.95-9-28.2-52.9-74-107-167-222-336-513
EPS, basic-5.96-6.68-2.23-2.09-2.42-2.80-3.15-3.69-3.69-4.95
EPS, diluted-5.96-6.68-2.23-2.09-2.42-2.80-3.15-3.69-3.69-4.95
Shares, basic (weighted)1.011.3712.124.230.438.45258.180.894.1
Shares, diluted (weighted)1.011.3712.124.230.438.45258.180.894.1

Balance sheet

FY2016FY2018FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Cash and equivalents12.214.24540.393.120132.754.9265102
Short-term investments11978.177.81333025041,090926
Receivables00.59
Inventory02.02
Other current assets0.240.880.671.020.911.930.452.393.46
Total current assets15.21671231773453455741,3751,048
Property, plant and equipment0.44.233.953.182.833.510.912.114.3
Lease right-of-use assets2.512.231.891.4946.543.540.5
Other non-current assets0.030.080.0400.0422.83
Total assets15.61711301833513526351,4351,126
Accounts payable0.41.465.55.593.426.886.555.8522.6
Accrued liabilities0.184.19
Deferred revenue2.22.062.181.24
Total current liabilities0.97.938.3410.51627.743.959.785.1
Lease liabilities4.854.013.072.0247.644.642.1
Other non-current liabilities00.833.24
Total liabilities0.9211.213.214.519.135.896.2110134
Paid-in capital1.242042113376087591,1922,2762,408
Retained earnings-16.3-43.4-93.8-168-275-439-654-952-1,417
Other comprehensive income0.060.150.03-0.38-3.930.980.961.87
Shareholders' equity-6.2-151601171693323165391,325992
Total equity-6.2-151601171693323165391,325992
Total liabilities and equity15.61711301833513526351,4351,126
Shares outstanding1.550.0224.33347.653.968.292.995.6

Cash flow statement

FY2016FY2018FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Net income-6.02-9.16-27.1-50.4-73.8-108-164-215-298-465
Depreciation and amortization0.090.130.470.890.950.920.981.12.83.9
Stock-based compensation0.270.272.326.2910.417.428.340.969.491
Deferred income tax000
Change in receivables00-0.59
Change in inventory00-2.02
Change in payables0.30.057.360.72.726.291112.413.329
Cash from operations-5.47-9.48-19.5-46.4-62-88.6-115-169-230-378
Capital expenditures-0.19-0.3-1.06-0.49-0.19-0.44-1.66-4.69-3.84-5.76
Purchases of investments-118-108-136-125-330-528-1,147-1,004
Cash from investing-0.19-0.3-11941.70.22-56.5-174-200-575174
Stock issued0.071060.131142501173709850
Cash from financing-0.0511.81700.071152531223911,01540.6
Net change in cash-5.712.0431.3-4.6552.8108-16722.2210-163
Free cash flow-5.66-9.78-20.5-46.9-62.2-89-117-173-234-384
Interest paid0.010.01
Income taxes paid000.09

Key metrics

Worked out from the statements above. Latest values use the trailing twelve months to June 30, 2026; growth uses fiscal years. Valuation uses the share price of $84.95 on August 31, 2026.

Profitability

MetricValueHow it is calculated
Operating margin-1,303.0%Operating income / revenue.
EBITDA margin-1,292.0%EBITDA (operating income + depreciation and amortization) / revenue.
Net margin-1,190.0%Net income / revenue.
FCF margin-1,009.0%Free cash flow (cash from operations - capital expenditures) / revenue.
Operating cash flow margin-1,002.0%Cash from operations / revenue.
Return on equity (ROE)-42.1%Net income / average shareholders' equity (opening and closing). Not shown when equity is negative.
Return on assets (ROA)-37.9%Net income / average total assets.
Return on invested capital (ROIC)-38.2%Approximation: operating income x (1 - tax rate) / average (total debt + equity - cash). Tax rate is the effective rate when between 0% and 50%, else 21%.
R&D / revenue890.6%Research and development expense / revenue.
Stock-based pay / revenue234.8%Stock-based compensation (from the cash flow statement) / revenue.
Capex / revenue6.3%Capital expenditures / revenue.
D&A / revenue10.1%Depreciation and amortization / revenue.

Growth

MetricValueHow it is calculated
Revenue growth, 1y640.7%Revenue vs the same period a year earlier. Only from a positive base.
Revenue CAGR, 3y17.6%Compound annual growth of revenue over 3 fiscal years: (end / start)^(1/3) - 1. Only when both values are positive.
Revenue CAGR, 5y155.3%Compound annual growth of revenue over 5 fiscal years: (end / start)^(1/5) - 1. Only when both values are positive.
Gross profit growth, 1y537.2%Gross profit vs the same period a year earlier. Only from a positive base.
Book value growth, 1y-25.1%Book value vs the same period a year earlier. Only from a positive base.
Book value CAGR, 3y46.4%Compound annual growth of book value over 3 fiscal years: (end / start)^(1/3) - 1. Only when both values are positive.
Book value CAGR, 5y42.5%Compound annual growth of book value over 5 fiscal years: (end / start)^(1/5) - 1. Only when both values are positive.
Total assets growth, 1y-21.5%Total assets vs the same period a year earlier. Only from a positive base.
Total assets CAGR, 3y47.3%Compound annual growth of total assets over 3 fiscal years: (end / start)^(1/3) - 1. Only when both values are positive.
Total assets CAGR, 5y43.8%Compound annual growth of total assets over 5 fiscal years: (end / start)^(1/5) - 1. Only when both values are positive.
Share count change, 1y16.4%Change in diluted weighted shares vs a year earlier. Negative means buybacks shrank the share count; positive means dilution.
Share count change per year, 3y21.9%Change in diluted weighted shares, per year over 3 years. Negative means buybacks shrank the share count; positive means dilution.
Share count change per year, 5y25.3%Change in diluted weighted shares, per year over 5 years. Negative means buybacks shrank the share count; positive means dilution.

Balance sheet health

MetricValueHow it is calculated
Current ratio15.6xCurrent assets / current liabilities.
Quick ratio15.2x(Cash + short-term investments + receivables) / current liabilities.
Cash ratio15.1x(Cash + short-term investments) / current liabilities.
Liabilities / assets9.8%Total liabilities / total assets.
Working capital$1.16BCurrent assets - current liabilities.
Tangible book value$1.19BShareholders' equity - goodwill - intangible assets.

Efficiency

MetricValueHow it is calculated
Asset turnover0.03xRevenue / average total assets.
Fixed asset turnover3.22xRevenue / average property, plant and equipment.
Receivables turnover3.53xRevenue / average receivables.
Days sales outstanding104 days365 x average receivables / revenue.

Per share

MetricValueHow it is calculated
EPS, diluted-$4.75Net income per diluted share, as reported (split-adjusted). Over the last twelve months: the four quarters summed, or net income / latest diluted shares when a quarter has no reported EPS.
Revenue per share$0.40Revenue / diluted weighted shares.
FCF per share-$4.03Free cash flow / diluted weighted shares.
Operating cash flow per share-$4.00Cash from operations / diluted weighted shares.
Book value per share$11.27Shareholders' equity / shares outstanding (diluted weighted shares when not reported).
Tangible book per share$11.27Tangible book value / shares outstanding.
Cash per share$11.40(Cash + short-term investments) / shares outstanding.

Valuation

MetricValueHow it is calculated
Market cap$9.01BShare price x shares outstanding.
Enterprise value$7.80BMarket cap + total debt - cash - short-term investments.
P/S214xMarket cap / revenue.
P/B7.56xMarket cap / shareholders' equity. Only when equity is positive.
Price / tangible book7.56xMarket cap / tangible book value, when positive.
EV/Sales185xEnterprise value / revenue.
FCF yield-4.7%Free cash flow / market cap.
Earnings yield-5.6%Net income / market cap (the inverse of P/E).
What was Crinetics Pharmaceuticals, Inc.'s revenue in fiscal 2025?

Crinetics Pharmaceuticals, Inc. reported revenue of $7.7M for fiscal 2025, 640.7% higher than the year before.

Was Crinetics Pharmaceuticals, Inc. profitable in fiscal 2025?

No. It reported a net loss of $465.3M.

How much free cash flow did Crinetics Pharmaceuticals, Inc. generate in fiscal 2025?

Cash from operations of $377.9M minus capital expenditures of $5.8M left free cash flow of -$383.7M.

Source: SEC EDGAR XBRL company facts. Where a company tags only year-to-date figures, quarters are worked out as differences. Where a line is not tagged it is left empty, never estimated.

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