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Ascendis Pharma A/S (ASND)

Ascendis Pharma A/S reported revenue of €720.1M in fiscal 2025, up 98.0% from a year earlier. It posted a net loss of €228M. At December 31, 2025 it held €616M in cash against €720.3M of debt.

Free, no password. An email when ASND files with the SEC.

Price
$256.93
-1.12% on the day · November 10, 2026
52-week range $188.07 to $282.15
Market cap
$15.9B
Revenue (FY2025)
€720.1M
+98.0% year on year
Net margin
-31.7%

Key facts about Ascendis Pharma A/S

Net worth
Ascendis Pharma A/S has a market value (market cap) of $15.9B at the latest share price, and shareholders' equity of -€162.8M on its balance sheet at December 31, 2025. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was €720.1M (+98.0% year on year), with a net loss of €228M.
Cash flow
In fiscal 2025 operations brought in €53.9M of cash.

What Ascendis Pharma A/S does

Ascendis Pharma A/S is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker ASND.

Revenue and profit by year

Revenue
FY18: €10.6M €10.6M FY18FY19: €13.4M €13.4M FY19FY20: €7M €7M FY20FY21: €7.8M €7.8M FY21FY22: €51.2M €51.2M FY22FY23: €266.7M €266.7M FY23FY24: €363.6M €363.6M FY24FY25: €720.1M €720.1M FY25
Net income
FY18: -€130.1M -€130.1M FY18FY19: -€218M -€218M FY19FY20: -€419M -€419M FY20FY21: -€383.6M -€383.6M FY21FY22: -€583.2M -€583.2M FY22FY23: -€481.4M -€481.4M FY23FY24: -€378.1M -€378.1M FY24FY25: -€228M -€228M FY25

Fiscal years as reported in annual reports. Amounts in EUR.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025€720.1M-€136.3M-€228M-€3.76n/a
2024€363.6M-€278.8M-€378.1M-€6.53n/a
2023€266.7M-€455.5M-€481.4M-€8.55-€469.8M
2022€51.2M-€561.8M-€583.2M-€10.40-€510.2M
2021€7.8M-€451.8M-€383.6M-€7.00-€441.4M
2020€7M-€330.6M-€419M-€8.28-€291.4M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Where ASND ranks in Health care

Revenue growth+98.0%
#56 of 532 in Health care · Top 10%
Net margin-31.7%
#363 of 544 in Health care · Bottom 33%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Ascendis Pharma A/S has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 6, 2026
  2. November 5, 2026
  3. October 26, 2026
  4. October 16, 2026
  5. October 14, 2026
  6. September 29, 2026
  7. September 15, 2026
  8. September 15, 2026
  9. September 9, 2026
  10. September 9, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on September 28, 2026. Insider transactions on SEC

Insider trades

What the people running Ascendis Pharma A/S did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders bought $492.7K and sold $872.9K worth of shares in the last 90 days.

Bought (open market)
$492.7K
last 90 days
Sold
$872.9K
last 90 days
Net sold
1,236
$380.3K
DateInsiderWhatSharesPriceValueFiling
September 8, 2026 Bodenhoff MadsSVP & PAO Exercised options 3,000 $110.00 $330K Form 4
September 8, 2026 Bodenhoff MadsSVP & PAO Sold 3,000 $270.19 $810.6K Form 4
September 2, 2026 Holtug LarsDirector Sold 236 $264.13 $62.3K Form 4
August 14, 2026 Bienaime Jean JacquesDirector Bought 1,100 $245.85 $270.4K Form 4
August 14, 2026 Bienaime Jean JacquesDirector Bought 900 $246.91 $222.2K Form 4
June 2, 2026 Smith Scott ThomasEVP & Chief Financial Officer Bought 100 $219.00 $21.9K Form 4
May 29, 2026 Smith Scott ThomasEVP & Chief Financial Officer Bought 250 $223.32 $55.8K Form 4
May 29, 2026 Bienaime Jean JacquesDirector Bought 200 $223.76 $44.8K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns ASND

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
RA Capital Management, L.P.13G, passive with 3 related filers 16.1% 9,710,428 November 14, 2024
T. Rowe Price Investment Management, Inc.13G, passive 10.5% 6,506,219 May 7, 2026
Westfield Capital Management Company, L.P.13G, passive 8.48% 5,185,696 February 11, 2026
Avoro Capital Advisors LLC13G, passive with 1 related filers 8.2% 4,988,888 November 14, 2024
Artisan Partners Limited Partnership13G, passive with 3 related filers 7.3% 4,411,111 November 12, 2024
Fmr LLC13G, passive with 1 related filers 6.6% 3,852,101 May 6, 2026
Janus Henderson Group PLC13G, passive 6% 3,719,452 May 15, 2026

Latest filings below 5%: Artisan Partners Asset Management Inc. 4.2% (August 13, 2026); Capital International Investors 3.2% (May 14, 2026).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 311 managers reported a position.

HolderSharesValueChange on quarter
RA Capital Management, L.P.10,281,496$2.74B0
Avoro Capital Advisors LLC5,111,111$1.36B+48,611
Westfield Capital Management Co LP4,798,267$1.28B-15,173
Jupiter Topco LLC3,648,772$973.4Mnew
Fmr LLC3,545,575$945.7M-331,026
Artisan Partners Limited Partnership2,634,024$702.5M-596,164
BlackRock, Inc.2,211,833$589.9M+1,550,779
Capital International Investors1,988,614$530.4M+29,771
Massachusetts Financial Services Co1,875,301$500.1M+14,632
Franklin Resources Inc1,862,503$496.8M-189,445
Wellington Management Group Llp1,548,636$413.1M-208,997
American Century Companies Inc1,400,575$373.6M+3,456
Perceptive Advisors LLC1,163,721$310.4M-367,700
Capital World Investors906,081$241.7M+5,564
Principal Financial Group Inc873,502$233M-22,895
Polar Capital Holdings Plc616,908$164.5M-34,804
Goldman Sachs Group Inc559,534$149.2M-6,658
Morgan Stanley544,393$145.2M-61,955
State Street Corp513,969$137.1M+426,635
Invesco Ltd.414,196$110.5M+52,087

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

3 insiders reported holding 11,267 shares in total, about $2.9M at the last price.

HolderSharesAs of
Smith Scott ThomasEVP & Chief Financial Officer 4,367 June 2, 2026
Holtug LarsDirector 4,000 September 2, 2026
Bienaime Jean JacquesDirector 2,900 August 14, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about ASND

What does Ascendis Pharma A/S do?

Ascendis Pharma A/S is a company in the Health care sector, listed on NASDAQ as ASND. Its shares trade on NASDAQ under the ticker ASND.

What is Ascendis Pharma A/S's net worth?

Ascendis Pharma A/S has a market value (market cap) of $15.9B at the latest share price, and shareholders' equity of -€162.8M on its balance sheet at December 31, 2025. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Ascendis Pharma A/S profitable?

No. In fiscal 2025 it reported a net loss of €228M on revenue of €720.1M.

How much revenue does Ascendis Pharma A/S make?

In fiscal 2025 Ascendis Pharma A/S reported revenue of €720.1M. That is 98.0% more than a year earlier.

When did Ascendis Pharma A/S last report?

Its newest filing of any kind is the foreign issuer update from November 6, 2026.

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Where the numbers come from

Financial figures are the values Ascendis Pharma A/S tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.