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NASDAQ · Health careAscendis Pharma A/S (ASND)
Ascendis Pharma A/S reported revenue of €720.1M in fiscal 2025, up 98.0% from a year earlier. It posted a net loss of €228M. At December 31, 2025 it held €616M in cash against €720.3M of debt.
Key facts about Ascendis Pharma A/S
- Net worth
- Ascendis Pharma A/S has a market value (market cap) of $15.9B at the latest share price, and shareholders' equity of -€162.8M on its balance sheet at December 31, 2025. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
- Revenue and profit
- In fiscal 2025 revenue was €720.1M (+98.0% year on year), with a net loss of €228M.
- Cash flow
- In fiscal 2025 operations brought in €53.9M of cash.
What Ascendis Pharma A/S does
Ascendis Pharma A/S is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker ASND.
Revenue and profit by year
Key figures
| Fiscal year | Revenue | Net income | Diluted EPS | Free cash flow |
|---|---|---|---|---|
| 2025 | €720.1M | -€228M | -€3.76 | n/a |
| 2024 | €363.6M | -€378.1M | -€6.53 | n/a |
| 2023 | €266.7M | -€481.4M | -€8.55 | -€469.8M |
| 2022 | €51.2M | -€583.2M | -€10.40 | -€510.2M |
| 2021 | €7.8M | -€383.6M | -€7.00 | -€441.4M |
| 2020 | €7M | -€419M | -€8.28 | -€291.4M |
Earnings: every quarter and the next report date
Full financial statements: income, balance sheet and cash flow
Where ASND ranks in Health care
Latest SEC filings
What Ascendis Pharma A/S has filed recently, newest first. Each links to the original document on SEC EDGAR.
- November 6, 2026
- November 5, 2026Passive stake changed SCHEDULE 13G/A
- October 26, 2026
- October 16, 2026
- October 14, 2026
- September 29, 2026
- September 15, 2026
- September 15, 2026
- September 9, 2026
- September 9, 2026
Insider trades
What the people running Ascendis Pharma A/S did with its shares, from the Form 4 filings they must send the SEC within two business days.
Insiders bought $492.7K and sold $872.9K worth of shares in the last 90 days.
| Date | Insider | What | Shares | Value |
|---|---|---|---|---|
| September 8, 2026 | Bodenhoff MadsSVP & PAO | Exercised options | 3,000 | $330K |
| September 8, 2026 | Bodenhoff MadsSVP & PAO | Sold | 3,000 | $810.6K |
| September 2, 2026 | Holtug LarsDirector | Sold | 236 | $62.3K |
| August 14, 2026 | Bienaime Jean JacquesDirector | Bought | 1,100 | $270.4K |
| August 14, 2026 | Bienaime Jean JacquesDirector | Bought | 900 | $222.2K |
| June 2, 2026 | Smith Scott ThomasEVP & Chief Financial Officer | Bought | 100 | $21.9K |
| May 29, 2026 | Smith Scott ThomasEVP & Chief Financial Officer | Bought | 250 | $55.8K |
| May 29, 2026 | Bienaime Jean JacquesDirector | Bought | 200 | $44.8K |
Who owns ASND
Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.
5% holders
| Holder | Of class | Filed |
|---|---|---|
| RA Capital Management, L.P.13G, passive with 3 related filers | 16.1% | November 14, 2024 |
| T. Rowe Price Investment Management, Inc.13G, passive | 10.5% | May 7, 2026 |
| Westfield Capital Management Company, L.P.13G, passive | 8.48% | February 11, 2026 |
| Avoro Capital Advisors LLC13G, passive with 1 related filers | 8.2% | November 14, 2024 |
| Artisan Partners Limited Partnership13G, passive with 3 related filers | 7.3% | November 12, 2024 |
| Fmr LLC13G, passive with 1 related filers | 6.6% | May 6, 2026 |
| Janus Henderson Group PLC13G, passive | 6% | May 15, 2026 |
Largest institutional holders
Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 311 managers reported a position.
| Holder | Shares | Change on quarter |
|---|---|---|
| RA Capital Management, L.P. | 10,281,496 | 0 |
| Avoro Capital Advisors LLC | 5,111,111 | +48,611 |
| Westfield Capital Management Co LP | 4,798,267 | -15,173 |
| Jupiter Topco LLC | 3,648,772 | new |
| Fmr LLC | 3,545,575 | -331,026 |
| Artisan Partners Limited Partnership | 2,634,024 | -596,164 |
| BlackRock, Inc. | 2,211,833 | +1,550,779 |
| Capital International Investors | 1,988,614 | +29,771 |
| Massachusetts Financial Services Co | 1,875,301 | +14,632 |
| Franklin Resources Inc | 1,862,503 | -189,445 |
| Wellington Management Group Llp | 1,548,636 | -208,997 |
| American Century Companies Inc | 1,400,575 | +3,456 |
| Perceptive Advisors LLC | 1,163,721 | -367,700 |
| Capital World Investors | 906,081 | +5,564 |
| Principal Financial Group Inc | 873,502 | -22,895 |
| Polar Capital Holdings Plc | 616,908 | -34,804 |
| Goldman Sachs Group Inc | 559,534 | -6,658 |
| Morgan Stanley | 544,393 | -61,955 |
| State Street Corp | 513,969 | +426,635 |
| Invesco Ltd. | 414,196 | +52,087 |
Insiders
3 insiders reported holding 11,267 shares in total, about $2.9M at the last price.
| Holder | Shares |
|---|---|
| Smith Scott ThomasEVP & Chief Financial Officer | 4,367 |
| Holtug LarsDirector | 4,000 |
| Bienaime Jean JacquesDirector | 2,900 |
Questions about ASND
What does Ascendis Pharma A/S do?
Ascendis Pharma A/S is a company in the Health care sector, listed on NASDAQ as ASND. Its shares trade on NASDAQ under the ticker ASND.
What is Ascendis Pharma A/S's net worth?
Ascendis Pharma A/S has a market value (market cap) of $15.9B at the latest share price, and shareholders' equity of -€162.8M on its balance sheet at December 31, 2025. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Is Ascendis Pharma A/S profitable?
No. In fiscal 2025 it reported a net loss of €228M on revenue of €720.1M.
How much revenue does Ascendis Pharma A/S make?
In fiscal 2025 Ascendis Pharma A/S reported revenue of €720.1M. That is 98.0% more than a year earlier.
When did Ascendis Pharma A/S last report?
Its newest filing of any kind is the foreign issuer update from November 6, 2026.
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Where the numbers come from
Financial figures are the values Ascendis Pharma A/S tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.
Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.