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NASDAQ · Health care

Arrowhead Pharmaceuticals, Inc. (ARWR)

Arrowhead Pharmaceuticals, Inc. brought in $669.5M of revenue over the twelve months to June 30, 2026, up 16.8% from a year earlier. It posted a net loss of $320M. Operating cash flow minus capital spending left $156.9M of free cash flow in fiscal 2025. At June 30, 2026 it held $54.8M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 4, 2026.

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Price
$49.00
-0.49% on the day · November 10, 2026
52-week range $37.06 to $95.49
Market cap
$6.9B
Revenue (last 12 months)
$669.5M
+16.8% year on year
Net margin
-47.8%

Key facts about Arrowhead Pharmaceuticals, Inc.

Net worth
Arrowhead Pharmaceuticals, Inc. has a market value (market cap) of $6.9B at the latest share price, and shareholders' equity of $465.5M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $829.4M (+23,258.2% year on year), with a net loss of $1.6M. Over the 12 months to June 30, 2026: revenue $669.5M, net loss $320M.
Cash flow
In fiscal 2025 operations brought in $179.6M of cash; after $22.7M of capital spending, free cash flow was $156.9M.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on August 4, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR
Next earnings report
Arrowhead Pharmaceuticals, Inc.'s next report is expected around November 24, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

What Arrowhead Pharmaceuticals, Inc. does

Arrowhead Pharmaceuticals, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker ARWR.

Revenue and profit by year

Revenue
FY18: $16.1M $16.1M FY18FY19: $168.8M $168.8M FY19FY20: $88M $88M FY20FY21: $138.3M $138.3M FY21FY22: $243.2M $243.2M FY22FY23: $240.7M $240.7M FY23FY24: $3.6M $3.6M FY24FY25: $829.4M $829.4M FY25
Net income
FY18: -$54.5M -$54.5M FY18FY19: $68M $68M FY19FY20: -$84.6M -$84.6M FY20FY21: -$140.8M -$140.8M FY21FY22: -$176.1M -$176.1M FY22FY23: -$205.3M -$205.3M FY23FY24: -$599.5M -$599.5M FY24FY25: -$1.6M -$1.6M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$829.4M$98.3M-$1.6M-$0.01$156.9M
2024$3.6M-$601.1M-$599.5M-$5.00-$604.3M
2023$240.7M-$205M-$205.3M-$1.92-$330.6M
2022$243.2M-$178.5M-$176.1M-$1.67-$188.9M
2021$138.3M-$149M-$140.8M-$1.36$147.7M
2020$88M-$93.2M-$84.6M-$0.84-$107.8M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around November 24, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 25, 2025. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where ARWR ranks in Health care

Revenue$829.4M
#166 of 751 in Health care · Top 22%
Revenue growth+23,258.2%
#3 of 532 in Health care · Top 1%
Net margin-0.2%
#222 of 544 in Health care · Top 41%
Free cash flow margin18.9%
#66 of 490 in Health care · Top 13%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Arrowhead Pharmaceuticals, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 5, 2026
  2. November 4, 2026
  3. August 14, 2026
  4. August 4, 2026
  5. August 4, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue rose 171% to $75.3M versus the same quarter last year; diluted EPS -$1.36 versus -$1.26.
  6. July 31, 2026
  7. July 27, 2026
  8. June 16, 2026
  9. May 7, 2026
  10. May 7, 2026
    Quarterly report 10-Q · period to March 31, 2026Revenue fell 86% to $73.7M versus the same quarter last year; diluted EPS -$0.93 versus $2.75.

Recent insider filings (Forms 3, 4 and 144): 10, the latest on August 20, 2026. Insider transactions on SEC

What is ARWR worth? A DCF from its reported cash flow

Insider trades

What the people running Arrowhead Pharmaceuticals, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $1.2M worth of shares in the last 90 days and bought none on the open market.

Bought (open market)
$0
last 90 days
Sold
$1.2M
last 90 days
Net sold
13,600
$1.2M
DateInsiderWhatSharesPriceValueFiling
August 18, 2026 Olukotun Adeoye YDirector Sold 2,000 $86.96 $173.9K Form 4
August 18, 2026 Perry Michael SDirector Sold 11,600 $87.30 $1M Form 4
June 15, 2026 Cohen Matthew GregoryDirector Received as pay 11,882 - - Form 4
May 12, 2026 Lu HongboDirector Soldpre-planned (10b5-1) 2,970 $76.88 $228.3K Form 4
April 23, 2026 Hamilton James CChief Medical Officer Soldpre-planned (10b5-1) 10,000 $75.00 $750K Form 4
April 22, 2026 Apel Daniel JosephChief Financial Officer Soldpre-planned (10b5-1) 3,208 $70.11 $224.9K Form 4
April 22, 2026 Apel Daniel JosephChief Financial Officer Soldpre-planned (10b5-1) 1,157 $70.45 $81.5K Form 4
April 22, 2026 Apel Daniel JosephChief Financial Officer Soldpre-planned (10b5-1) 8,730 $71.92 $627.9K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns ARWR

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Avoro Capital Advisors LLC13G, passive with 1 related filers 9.64% 13,823,383 August 14, 2026
Fmr LLC13G, passive with 1 related filers 5.2% 7,349,107 May 6, 2026
Vanguard Capital Management13G, passive 5.05% 7,081,293 April 29, 2026

Latest filings below 5%: Vanguard Portfolio Management 4.53% (July 31, 2026); The Vanguard Group 0% (March 26, 2026).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 499 managers reported a position.

HolderSharesValueChange on quarter
BlackRock, Inc.14,830,553$1.21B-3,330,966
Avoro Capital Advisors LLC11,355,555$925.6M+655,556
Fmr LLC8,039,804$655.3M+773,152
Vanguard Portfolio Management LLC6,351,355$517.7M-794,781
Vanguard Capital Management LLC6,110,953$498.1M+78,537
State Street Corp5,694,640$464.2M-801,490
Norges Bank3,896,536$317.6Mnew
Invesco Ltd.3,883,976$316.6M+603,329
Geode Capital Management, LLC3,530,612$298.8M-748,216
Fred Alger Management, LLC3,301,919$269.1M-40,574
Baker Bros. Advisors LP1,992,783$162.4M0
Siren, L.L.C.1,715,476$139.8M+100,000
Vestal Point Capital, LP1,575,000$128.4M-700,000
Deerfield Management Company, L.P.1,389,055$113.2M-184,242
First Trust Advisors LP1,352,918$110.3M+1,203,770
Driehaus Capital Management LLC1,350,556$110.1M+160,221
Jupiter Topco LLC1,221,596$99.6Mnew
Northern Trust Corp1,192,868$97.2M-462,969
Dimensional Fund Advisors LP1,181,608$96.3M+573,077
Goldman Sachs Group Inc1,150,007$93.7M-589,916

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

12 insiders reported holding 5,144,517 shares in total, about $252.1M at the last price.

HolderSharesAs of
Anzalone Christopher RichardChief Executive Officer, Director 3,792,739 January 2, 2026
O'Brien PatrickCOO 547,408 January 6, 2026
Hamilton James CChief Medical Officer 226,958 April 23, 2026
Apel Daniel JosephChief Financial Officer 162,905 April 22, 2026
Perry Michael SDirector 111,459 August 18, 2026
Ferrari MauroDirector 69,053 December 26, 2025
Waddill William D.Director 56,563 December 19, 2025
Lu HongboDirector 52,012 May 12, 2026
Ingram Douglas SDirector 46,215 December 16, 2025
Vakiener VictoriaDirector 35,723 December 19, 2025

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about ARWR

What does Arrowhead Pharmaceuticals, Inc. do?

Arrowhead Pharmaceuticals, Inc. is a company in the Health care sector, listed on NASDAQ as ARWR. Its shares trade on NASDAQ under the ticker ARWR.

What is Arrowhead Pharmaceuticals, Inc.'s net worth?

Arrowhead Pharmaceuticals, Inc. has a market value (market cap) of $6.9B at the latest share price, and shareholders' equity of $465.5M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Arrowhead Pharmaceuticals, Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $320M on revenue of $669.5M.

How much revenue does Arrowhead Pharmaceuticals, Inc. make?

Over the twelve months to June 30, 2026 Arrowhead Pharmaceuticals, Inc. reported revenue of $669.5M. That is 16.8% more than a year earlier.

When did Arrowhead Pharmaceuticals, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 4, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the passive stake changed from November 5, 2026.

When is Arrowhead Pharmaceuticals, Inc.'s next earnings report?

Arrowhead Pharmaceuticals, Inc.'s next report is expected around November 24, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Arrowhead Pharmaceuticals, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.