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NASDAQ · Health care

Adagene Inc. (ADAG)

Adagene Inc. reported revenue of $7.7M in fiscal 2025, up 7,332.8% from a year earlier. It posted a net loss of $17.6M. In fiscal 2025 capital spending exceeded operating cash flow by $15.7M. At December 31, 2025 it held $74.5M in cash against $1.8M of debt. Its latest periodic report to the SEC is the annual report (foreign issuer) (20-F) filed on April 1, 2026.

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Price
$2.07
-2.36% on the day · November 10, 2026
52-week range $1.50 to $4.85
Market cap
$136.7M
Revenue (FY2025)
$7.7M
+7,332.8% year on year
Net margin
-229.6%

Key facts about Adagene Inc.

Net worth
Adagene Inc. has a market value (market cap) of $136.7M at the latest share price, and shareholders' equity of $35.3M on its balance sheet at December 31, 2025. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $7.7M (+7,332.8% year on year), with a net loss of $17.6M.
Cash flow
In fiscal 2025 operations used $15.7M of cash.
Latest report
The latest periodic report (annual report (foreign issuer), 20-F) was filed with the SEC on April 1, 2026 and covers the period to December 31, 2025. Open on SEC EDGAR

What Adagene Inc. does

Adagene Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker ADAG.

Revenue and profit by year

Revenue
FY18: $1.5M $1.5M FY18FY20: $480K $480K FY20FY20: $700.9K $700.9K FY20FY21: $10.2M $10.2M FY21FY22: $9.3M $9.3M FY22FY23: $18.1M $18.1M FY23FY24: $103.2K $103.2K FY24FY25: $7.7M $7.7M FY25
Net income
FY18: -$15.3M -$15.3M FY18FY20: -$16.4M -$16.4M FY20FY20: -$42.4M -$42.4M FY20FY21: -$73.2M -$73.2M FY21FY22: -$80M -$80M FY22FY23: -$18.9M -$18.9M FY23FY24: -$33.4M -$33.4M FY24FY25: -$17.6M -$17.6M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$7.7M-$21.4M-$17.6M-$0.30-$15.7M
2024$103.2K-$36M-$33.4M-$0.59-$29.7M
2023$18.1M-$23.7M-$18.9M-$0.35-$28.5M
2022$9.3M-$83.9M-$80M-$1.48-$49.3M
2021$10.2M-$72.4M-$73.2M-$1.46-$45.9M
2020$700.9K-$43.2M-$42.4M-$2.67-$29.5M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Where ADAG ranks in Health care

Revenue$7.7M
#544 of 751 in Health care · Bottom 28%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Adagene Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 9, 2026
  2. September 25, 2026
  3. September 22, 2026
  4. September 10, 2026
  5. September 9, 2026
  6. August 14, 2026
  7. August 12, 2026
  8. July 6, 2026
  9. June 8, 2026
  10. May 15, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 2, 2026. Insider transactions on SEC

Insider trades

What the people running Adagene Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders bought $77.5K worth of shares on the open market in the last 90 days and sold none.

Bought (open market)
$77.5K
last 90 days
Sold
$0
last 90 days
Net bought
24,290
$77.5K
DateInsiderWhatSharesPriceValueFiling
September 23, 2026 Tam Man KinChief Financial Officer, Director Bought 2,000 $3.00 $6K Form 4
September 16, 2026 Luo PeterChief Executive Officer, Director Bought 20,290 $3.15 $64K Form 4
August 14, 2026 Do Cuong VDirector Bought 2,000 $3.75 $7.5K Form 4
August 5, 2026 Luo PeterChief Executive Officer, Director Bought 279 $3.65 $1K Form 4
August 4, 2026 Luo PeterChief Executive Officer, Director Bought 22,966 $3.65 $83.7K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns ADAG

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Peter Luo13D, may seek influence with 1 related filers 21.28% 12,008,498 March 1, 2024
HAN 2020 Irrevocable Trust13D, may seek influence with 1 related filers 11.2% 9,390,439 June 8, 2026
Janus Henderson Group PLC13G, passive 10.1% 6,666,666 May 7, 2026
Smith Vincent C13G, passive with 2 related filers 8.7% 5,095,351 January 29, 2026
OT Management, LLC13G, passive with 1 related filers 8.1% 3,567,653 February 3, 2025
Chernett Jorey13G, passive 5.1% 2,389,060 March 18, 2026

Latest filings below 5%: WuXi PharmaTech Healthcare Fund I L.P. 3.5% (August 14, 2026); General Atlantic Singapore Fund Pte. Ltd. 0% (February 17, 2026); Panacea Venture Healthcare Fund II, L.P. 3.8% (November 14, 2025); Fmr LLC 0.9% (July 2, 2025); FIL Limited 1.8% (May 12, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 36 managers reported a position.

HolderSharesValueChange on quarter
Jupiter Topco LLC6,666,666$28.1Mnew
Deerfield Management Company, L.P.2,666,666$11.2Mnew
Siren, L.L.C.2,666,666$11.2Mnew
Ameriprise Financial Inc1,716,711$7.2M+1,108,808
HSG Holding Ltd1,343,364$5.6M0
Squadron Capital Management LLC1,250,000$5.3Mnew
Dauntless Investment Group, LLC537,230$2.3M+502,455
Citadel Advisors LLC506,934$2.1Mnew
Exome Asset Management LLC488,293$2.1M-248,552
Birchview Capital, LP240,000$1Mnew
Moneta Group Investment Advisors LLC200,000$840Knew
Pathstone Holdings, LLC199,610$838.4Knew
Renaissance Technologies LLC146,500$615.3K+111,967
UBS Group AG124,063$521.1K+120,061
Goldman Sachs Group Inc105,598$443.5Knew
Quadrature Capital Ltd80,487$338K+68,870
Marshall Wace, Llp69,100$290.2Knew
Invesco Ltd.42,945$180.4K-4,179
SmartHarvest Portfolios, LLC41,694$175.1K+1,382
Kamunting Street Capital Management, L.P.38,070$160K0

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

3 insiders reported holding 102,535 shares in total, about $212.2K at the last price.

HolderSharesAs of
Luo PeterChief Executive Officer, Director 88,535 September 16, 2026
Tam Man KinChief Financial Officer, Director 12,000 September 23, 2026
Do Cuong VDirector 2,000 August 14, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about ADAG

What does Adagene Inc. do?

Adagene Inc. is a company in the Health care sector, listed on NASDAQ as ADAG. Its shares trade on NASDAQ under the ticker ADAG.

What is Adagene Inc.'s net worth?

Adagene Inc. has a market value (market cap) of $136.7M at the latest share price, and shareholders' equity of $35.3M on its balance sheet at December 31, 2025. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Adagene Inc. profitable?

No. In fiscal 2025 it reported a net loss of $17.6M on revenue of $7.7M.

How much revenue does Adagene Inc. make?

In fiscal 2025 Adagene Inc. reported revenue of $7.7M. That is 7,332.8% more than a year earlier.

When did Adagene Inc. last report?

Its most recent periodic report is the annual report (foreign issuer) (20-F) filed on April 1, 2026. It covers the period to December 31, 2025. Its newest filing of any kind is the foreign issuer update from November 9, 2026.

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Where the numbers come from

Financial figures are the values Adagene Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.