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NASDAQ · Health care

X4 Pharmaceuticals, Inc (XFOR)

X4 Pharmaceuticals, Inc brought in $17M of revenue over the twelve months to September 30, 2026, down 50.1% from a year earlier. It posted a net loss of $80.5M. In fiscal 2025 capital spending exceeded operating cash flow by $85.6M. At September 30, 2026 it held $185.8M in cash against $75M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 4, 2026.

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Price
$3.33
+4.72% on the day · November 9, 2026
52-week range $2.43 to $4.83
Market cap
$330.2M
Revenue (last 12 months)
$17M
-50.1% year on year
Net margin
-474.7%

Key facts about X4 Pharmaceuticals, Inc

Net worth
X4 Pharmaceuticals, Inc has a market value (market cap) of $330.2M at the latest share price, and shareholders' equity of $138.9M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $35.1M (+1,250.5% year on year), with a net loss of $79.2M. Over the 12 months to September 30, 2026: revenue $17M, net loss $80.5M.
Cash flow
In fiscal 2025 operations used $85.6M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 4, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
X4 Pharmaceuticals, Inc's next report is expected around March 16, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What X4 Pharmaceuticals, Inc does

X4 Pharmaceuticals, Inc is registered with the SEC under industry code SIC 2836 (Biological Products, (No Diagnostic Substances)). Its shares trade on NASDAQ under the ticker XFOR.

Revenue and profit by year

Revenue
FY18: $0 $0 FY18FY19: $0 $0 FY19FY20: $3M $3M FY20FY21: $0 $0 FY21FY22: $0 $0 FY22FY23: $0 $0 FY23FY24: $2.6M $2.6M FY24FY25: $35.1M $35.1M FY25
Net income
FY18: -$33.3M -$33.3M FY18FY19: -$52.8M -$52.8M FY19FY20: -$62.1M -$62.1M FY20FY21: -$88.7M -$88.7M FY21FY22: -$93.9M -$93.9M FY22FY23: -$101.2M -$101.2M FY23FY24: -$37.5M -$37.5M FY24FY25: -$79.2M -$79.2M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$35.1M-$86.9M-$79.2M-$1.87-$85.6M
2024$2.6M-$36.4M-$37.5M-$5.59-$131.2M
2023$0-$107.5M-$101.2M-$17.07-$96.6M
2022$0-$87.6M-$93.9M-$45.52-$77.2M
2021$0-$85.1M-$88.7M-$119.49-$71.5M
2020$3M-$59.9M-$62.1M-$92.54-$60.2M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around March 16, 2027.

Estimated from its filing rhythm: 52 weeks after its report of March 17, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where XFOR ranks in Health care

Revenue$35.1M
#434 of 751 in Health care · Bottom 42%
Revenue growth+1,250.5%
#8 of 532 in Health care · Top 1%
Net margin-225.6%
#484 of 544 in Health care · Bottom 11%
Free cash flow margin-243.8%
#445 of 490 in Health care · Bottom 9%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What X4 Pharmaceuticals, Inc has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 4, 2026
    Quarterly report 10-Q · period to September 30, 2026Revenue rose 63% to $2.9M versus the same quarter last year; diluted EPS -$0.16 versus -$0.69.
  2. October 29, 2026
  3. October 8, 2026
    Material agreement8-KX4 Pharmaceuticals entered into a senior secured term loan facility of up to $150.0 million with K2 HealthVentures and retired its previous debt.
  4. October 7, 2026
  5. September 21, 2026
  6. September 9, 2026
  7. September 8, 2026
  8. August 14, 2026
  9. August 14, 2026
  10. August 6, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue rose 346% to $8.8M versus the same quarter last year; diluted EPS -$0.13 versus -$3.47.

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 19, 2026. Insider transactions on SEC

Insider trades

What the people running X4 Pharmaceuticals, Inc did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders bought $11.9K and sold $33.7K worth of shares in the last 90 days.

Bought (open market)
$11.9K
last 90 days
Sold
$33.7K
last 90 days
Net sold
7,167
$21.8K
DateInsiderWhatSharesPriceValueFiling
October 16, 2026 Craig Adam RExecutive Chairman, Director Bought 4,600 $2.58 $11.9K Form 4
October 1, 2026 Kirske DavidChief Financial Officer Sold 11,767 $2.86 $33.7K Form 4
August 12, 2026 Craig Adam RExecutive Chairman, Director Sold 47,436 $4.44 $210.8K Form 4
August 12, 2026 Volpone JohnPresident Sold 24,576 $4.44 $109.2K Form 4
June 30, 2026 Kirske DavidChief Financial Officer Sold 8,543 $4.26 $36.4K Form 4
May 12, 2026 Kirske DavidChief Financial Officer Sold 16,961 $4.29 $72.8K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns XFOR

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Coastlands Capital LP13G, passive with 4 related filers 9.99% 2,491,638 October 3, 2025
Empery Asset Management, LP13G, passive with 1 related filers 9.99% 9,043,894 January 15, 2026
Fmr LLC13G, passive with 1 related filers 9.7% 8,499,100 February 5, 2026
Deep Track Capital, LP13G, passive with 3 related filers 8.33% 8,040,894 August 14, 2026
Perceptive Advisors LLC13G, passive with 2 related filers 8.1% 8,085,006 August 14, 2026
BCLS II Equity Opportunities, LP13G, passive with 5 related filers 7.43% 7,047,216 February 17, 2026
Saturn V Capital Management LP13G, passive with 1 related filers 7.36% 6,433,481 February 17, 2026
Growth Equity Opportunities 18 VGE, LLC13D, may seek influence with 11 related filers 6.2% 5,057,610 October 29, 2025
Trails Edge Capital Partners, LP13G, passive with 2 related filers 5.8% 5,227,222 February 17, 2026
Venrock Healthcare Capital Partners III, L.P.13G, passive with 6 related filers 5.6% 5,555,047 September 21, 2026

Latest filings below 5%: Bvf Partners L P 3.9% (February 17, 2026); Nantahala Capital Management, LLC 2.8% (February 13, 2026); Orbimed Advisors LLC 1.7% (August 14, 2025); The Vanguard Group 4.8% (January 31, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 88 managers reported a position.

HolderSharesValueChange on quarter
Morgan Stanley9,461,279$44.2M-5,713
Fmr LLC8,321,657$38.9M+218,257
Bain Capital Life Sciences Investors, LLC7,967,454$37.2M0
Perceptive Advisors LLC7,933,491$37M+1,195,843
Kalehua Capital Management LLC7,445,680$34.8M0
Saturn V Capital Management LP6,973,343$32.6M+516,697
Empery Asset Management, LP6,930,591$32.4M-2,013,527
Deep Track Capital, LP5,878,757$27.5M-460,778
BlackRock, Inc.5,554,906$25.9M+4,343,112
Nantahala Capital Management, LLC4,898,936$22.9M+2,449,468
Vanguard Capital Management LLC3,715,859$17.4M+218,247
Rosalind Advisors, Inc.3,214,766$15M0
Braidwell LP2,922,754$13.6M-350,200
Blackstone Inc.2,681,922$12.5M0
Trails Edge Capital Partners, LP2,571,478$12M0
Bvf Inc2,233,742$10.4M0
Geode Capital Management, LLC2,098,047$9.8M+1,158,321
Venrock Adviser, LLC1,934,253$9M+1,603,728
Samsara Biocapital, LLC1,395,587$6.5M-436,979
State Street Corp1,296,017$6.1M+892,483

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

3 insiders reported holding 754,539 shares in total, about $2.5M at the last price.

HolderSharesAs of
Craig Adam RExecutive Chairman, Director 333,251 October 16, 2026
Volpone JohnPresident 265,305 August 12, 2026
Kirske DavidChief Financial Officer 155,983 October 1, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about XFOR

What does X4 Pharmaceuticals, Inc do?

X4 Pharmaceuticals, Inc is a company in the Health care sector, listed on NASDAQ as XFOR. Its shares trade on NASDAQ under the ticker XFOR.

What is X4 Pharmaceuticals, Inc's net worth?

X4 Pharmaceuticals, Inc has a market value (market cap) of $330.2M at the latest share price, and shareholders' equity of $138.9M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is X4 Pharmaceuticals, Inc profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $80.5M on revenue of $17M.

How much revenue does X4 Pharmaceuticals, Inc make?

Over the twelve months to September 30, 2026 X4 Pharmaceuticals, Inc reported revenue of $17M. That is 50.1% less than a year earlier.

When did X4 Pharmaceuticals, Inc last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 4, 2026. It covers the period to September 30, 2026.

When is X4 Pharmaceuticals, Inc's next earnings report?

X4 Pharmaceuticals, Inc's next report is expected around March 16, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values X4 Pharmaceuticals, Inc tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.