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Twist Bioscience Corp (TWST)

Twist Bioscience Corp brought in $431.8M of revenue over the twelve months to June 30, 2026, up 19.2% from a year earlier. It posted a net loss of $136.7M. In fiscal 2025 capital spending exceeded operating cash flow by $75.6M. At June 30, 2026 it held $117.4M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 3, 2026.

Free, no password. An email when TWST files with the SEC.

Price
$132.13
-2.37% on the day · November 10, 2026
52-week range $23.30 to $219.71
Market cap
$8.8B
Revenue (last 12 months)
$431.8M
+19.2% year on year
Net margin
-31.7%

Key facts about Twist Bioscience Corp

Net worth
Twist Bioscience Corp has a market value (market cap) of $8.8B at the latest share price, and shareholders' equity of $445.7M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $376.6M (+20.3% year on year), with a net loss of $77.7M. Over the 12 months to June 30, 2026: revenue $431.8M, net loss $136.7M.
Cash flow
In fiscal 2025 operations used $47.6M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on August 3, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR
Next earnings report
Twist Bioscience Corp's next report is expected around November 13, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

What Twist Bioscience Corp does

Twist Bioscience Corp is registered with the SEC under industry code SIC 2836 (Biological Products, (No Diagnostic Substances)). Its shares trade on NASDAQ under the ticker TWST.

Revenue and profit by year

Revenue
FY19: $25.4M $25.4M FY19FY19: $54.4M $54.4M FY19FY20: $90.1M $90.1M FY20FY21: $132.3M $132.3M FY21FY22: $203.6M $203.6M FY22FY23: $245.1M $245.1M FY23FY24: $313M $313M FY24FY25: $376.6M $376.6M FY25
Net income
FY19: -$71.2M -$71.2M FY19FY19: -$107.7M -$107.7M FY19FY20: -$139.9M -$139.9M FY20FY21: -$152.1M -$152.1M FY21FY22: -$217.9M -$217.9M FY22FY23: -$204.6M -$204.6M FY23FY24: -$208.7M -$208.7M FY24FY25: -$77.7M -$77.7M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$376.6M-$136.3M-$77.7M-$1.30-$75.6M
2024$313M-$220.8M-$208.7M-$3.60-$69.2M
2023$245.1M-$217.2M-$204.6M-$3.60-$170.3M
2022$203.6M-$234.8M-$217.9M-$4.04-$226.2M
2021$132.3M-$152.7M-$152.1M-$3.15-$139.3M
2020$90.1M-$140.1M-$139.9M-$3.57-$152.1M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around November 13, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 14, 2025. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where TWST ranks in Health care

Revenue$376.6M
#223 of 751 in Health care · Top 30%
Revenue growth+20.3%
#179 of 532 in Health care · Top 34%
Net margin-20.6%
#325 of 544 in Health care · Bottom 40%
Free cash flow margin-20.1%
#327 of 490 in Health care · Bottom 33%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Twist Bioscience Corp has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 5, 2026
  2. September 8, 2026
  3. September 8, 2026
  4. August 19, 2026
  5. August 19, 2026
  6. August 14, 2026
  7. August 14, 2026
  8. August 14, 2026
  9. August 13, 2026
  10. August 11, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on November 5, 2026. Insider transactions on SEC

Insider trades

What the people running Twist Bioscience Corp did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $99.9M worth of shares in the last 90 days and bought none on the open market. Most of the selling (84%) was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$99.9M
last 90 days
Net sold
638,941
$99.9M
DateInsiderWhatSharesPriceValueFiling
November 3, 2026 Werner Robert F.Chief Accounting Officer Sold 148 $135.40 $20K Form 4
November 3, 2026 Leproust Emily M.Chief Executive Officer, Director Sold 4,573 $135.40 $619.2K Form 4
November 3, 2026 Green PaulaSVP of Human Resources Sold 1,007 $135.40 $136.3K Form 4
November 3, 2026 Finn Patrick JohnPresident and COO Sold 2,565 $135.40 $347.3K Form 4
November 3, 2026 Cho DennisSee Remarks Sold 949 $135.40 $128.5K Form 4
October 23, 2026 Finn Patrick JohnPresident and COO Sold 2,245 $134.59 $302.2K Form 4
October 9, 2026 Laponis AdamChief Financial Officer Sold 2,462 $156.30 $384.8K Form 4
October 5, 2026 Leproust Emily M.Chief Executive Officer, Director Soldpre-planned (10b5-1) 1,840 $200.44 $368.8K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns TWST

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Fmr LLC13G, passive with 1 related filers 13.2% 8,760,081 September 8, 2026
Artisan Partners Asset Management Inc.13G, passive with 3 related filers 7.7% 4,802,017 August 13, 2026
T. Rowe Price Associates, Inc.13G, passive 5.8% 3,634,470 August 14, 2026
ARK Investment Management LLC13G, passive with 1 related filers 5.11% 3,385,850 September 8, 2026
Vanguard Capital Management13G, passive 5.05% 3,101,909 April 30, 2026

Latest filings below 5%: EdgePoint Investment Group Inc. 4.21% (August 14, 2026); William Blair Investment Management, LLC 3.5% (August 11, 2026); The Vanguard Group 0% (March 27, 2026).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 336 managers reported a position.

HolderSharesValueChange on quarter
BlackRock, Inc.5,833,891$600.2M+279,529
Artisan Partners Limited Partnership4,802,017$494M-1,565,760
Fmr LLC4,703,044$483.8M+2,813,099
ARK Investment Management LLC4,549,803$468.1M-1,792,930
State Street Corp3,232,532$332.6M-438,150
Vanguard Portfolio Management LLC2,824,989$290.6M+175,888
Vanguard Capital Management LLC2,699,280$277.7M+60,236
EdgePoint Investment Group Inc.2,521,635$259.4M-2,860,886
William Blair Investment Management, LLC2,174,594$223.7M-3,095,124
Farallon Capital Management, L.L.C.2,136,400$219.8M+708,750
Invesco Ltd.1,928,229$198.4M-243,669
Geode Capital Management, LLC1,619,361$166.6M+99,648
Goldman Sachs Group Inc1,408,418$144.9M-297,128
Morgan Stanley1,189,861$122.4M+643,016
D. E. Shaw & Co., Inc.1,185,605$122M+1,138,961
Baillie Gifford & Co1,086,779$111.8M-128,372
Driehaus Capital Management LLC1,022,526$105.2M+437,830
Sumitomo Mitsui Trust Group, Inc.1,000,344$102.9M-495,755
Amova Asset Management Americas, Inc.999,734$102.8M-496,365
Bank of America Corp922,647$94.9M+338,386

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

13 insiders reported holding 1,215,886 shares in total, about $160.7M at the last price.

HolderSharesAs of
Leproust Emily M.Chief Executive Officer, Director 558,187 November 3, 2026
Finn Patrick JohnPresident and COO 180,278 November 3, 2026
Green PaulaSVP of Human Resources 105,625 November 3, 2026
Laponis AdamChief Financial Officer 98,114 October 9, 2026
Cho DennisSee Remarks 62,840 November 3, 2026
Werner Robert F.Chief Accounting Officer 42,769 November 3, 2026
Chan NelsonDirector 33,251 February 5, 2026
Ragusa Robert PDirector 28,983 February 5, 2026
Crandell KeithDirector 27,571 February 5, 2026
Starovasnik Melissa A.Director 22,222 May 28, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about TWST

What does Twist Bioscience Corp do?

Twist Bioscience Corp is a company in the Health care sector, listed on NASDAQ as TWST. Its shares trade on NASDAQ under the ticker TWST.

What is Twist Bioscience Corp's net worth?

Twist Bioscience Corp has a market value (market cap) of $8.8B at the latest share price, and shareholders' equity of $445.7M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Twist Bioscience Corp profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $136.7M on revenue of $431.8M.

How much revenue does Twist Bioscience Corp make?

Over the twelve months to June 30, 2026 Twist Bioscience Corp reported revenue of $431.8M. That is 19.2% more than a year earlier.

When did Twist Bioscience Corp last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 3, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the passive stake changed from November 5, 2026.

When is Twist Bioscience Corp's next earnings report?

Twist Bioscience Corp's next report is expected around November 13, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Twist Bioscience Corp tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.