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NASDAQ · Technology

SOPHiA GENETICS SA (SOPH)

SOPHiA GENETICS SA reported revenue of $77.3M in fiscal 2025, up 18.6% from a year earlier. It posted a net loss of $79M. In fiscal 2025 capital spending exceeded operating cash flow by $36.5M. At December 31, 2025 it held $70.3M in cash. Its latest periodic report to the SEC is the annual report (foreign issuer) (20-F) filed on March 3, 2026.

Free, no password. An email when SOPH files with the SEC.

Price
$7.86
+4.94% on the day · November 10, 2026
52-week range $3.83 to $8.98
Market cap
$669.1M
Revenue (FY2025)
$77.3M
+18.6% year on year
Net margin
-102.2%

Key facts about SOPHiA GENETICS SA

Net worth
SOPHiA GENETICS SA has a market value (market cap) of $669.1M at the latest share price, and shareholders' equity of $47.1M on its balance sheet at December 31, 2025. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $77.3M (+18.6% year on year), with a net loss of $79M.
Cash flow
In fiscal 2025 operations used $35.9M of cash.
Latest report
The latest periodic report (annual report (foreign issuer), 20-F) was filed with the SEC on March 3, 2026 and covers the period to December 31, 2025. Open on SEC EDGAR

What SOPHiA GENETICS SA does

SOPHiA GENETICS SA is registered with the SEC under industry code SIC 7374 (Services-Computer Processing & Data Preparation). Its shares trade on NASDAQ under the ticker SOPH.

Revenue and profit by year

Revenue
FY19: $25.4M $25.4M FY19FY21: $28.4M $28.4M FY21FY21: $40.5M $40.5M FY21FY22: $47.6M $47.6M FY22FY23: $62.4M $62.4M FY23FY24: $65.2M $65.2M FY24FY25: $77.3M $77.3M FY25
Net income
FY19: -$33.8M -$33.8M FY19FY21: -$39.3M -$39.3M FY21FY21: -$73.7M -$73.7M FY21FY22: -$87.4M -$87.4M FY22FY23: -$79M -$79M FY23FY24: -$62.5M -$62.5M FY24FY25: -$79M -$79M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$77.3M-$70.9M-$79M-$1.17-$36.5M
2024$65.2M-$66.6M-$62.5M-$0.95-$44.8M
2023$62.4M-$74.8M-$79M-$1.22-$54.7M
2022$47.6M-$87.8M-$87.4M-$1.36-$74.2M
2021$40.5M-$71.5M-$73.7M-$1.33-$60.6M
2021$28.4M-$37.4M-$39.3M-$0.93-$32.2M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Where SOPH ranks in Technology

Revenue$77.3M
#465 of 751 in Technology · Bottom 38%
Revenue growth+18.6%
#187 of 604 in Technology · Top 31%
Net margin-102.2%
#576 of 611 in Technology · Bottom 6%
Free cash flow margin-47.2%
#525 of 568 in Technology · Bottom 8%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Technology

Latest SEC filings

What SOPHiA GENETICS SA has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 3, 2026
  2. August 4, 2026
  3. June 22, 2026
  4. June 22, 2026
  5. June 4, 2026
  6. May 19, 2026
  7. May 8, 2026
  8. May 5, 2026
  9. March 3, 2026
  10. March 3, 2026
    Annual report (foreign issuer) 20-F · period to December 31, 2025Revenue rose 19% to $77.3M versus the prior year; diluted EPS -$1.17 versus -$0.95.

Recent insider filings (Forms 3, 4 and 144): 10, the latest on November 9, 2026. Insider transactions on SEC

Insider trades

What the people running SOPHiA GENETICS SA did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders bought $278.4K and sold $1.6M worth of shares in the last 90 days. All of the selling was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$278.4K
last 90 days
Sold
$1.6M
last 90 days
Net sold
156,162
$1.3M
DateInsiderWhatSharesPriceValueFiling
November 6, 2026 Muken RossChief Executive Officer, Director Bought 20,000 $6.86 $137.2K Form 4
November 6, 2026 Cardoza GeorgeChief Financial Officer Bought 20,000 $7.06 $141.2K Form 4
October 13, 2026 Xu ZhenyuChief Scientific Officer Soldpre-planned (10b5-1) 4,000 $7.18 $28.7K Form 4
October 12, 2026 Camblong JurgiExecutive Chairman, Director Soldpre-planned (10b5-1) 8,500 $7.26 $61.7K Form 4
October 12, 2026 Menu PhilippeChief Medical Officer Soldpre-planned (10b5-1) 5,000 $7.26 $36.3K Form 4
October 5, 2026 Muken RossChief Executive Officer, Director Soldpre-planned (10b5-1) 9,838 $8.13 $80K Form 4
October 5, 2026 Xu ZhenyuChief Scientific Officer Soldpre-planned (10b5-1) 7,394 $8.12 $60.1K Form 4
October 5, 2026 Camblong JurgiExecutive Chairman, Director Soldpre-planned (10b5-1) 40,172 $8.13 $326.5K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns SOPH

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Generation Investment Management LLP13G, passive with 2 related filers 10.22% 6,789,560 November 13, 2024
Akre Capital Management, LLC13G, passive with 2 related filers 5.6% 3,719,140 June 27, 2025

Latest filings below 5%: Balderton Capital VI, S.L.P. 4.9% (February 11, 2026).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 72 managers reported a position.

HolderSharesValueChange on quarter
Generation Investment Management Llp6,789,560$39.2M0
AIGH Capital Management LLC3,954,194$22.8Mnew
Akre Capital Management LLC3,719,140$21.5M0
Royce & Associates LP3,381,736$19.5M+1,565,424
Principal Financial Group Inc2,364,256$13.6M+955,014
Ameriprise Financial Inc2,216,752$12.8Mnew
Banque Pictet & Cie SA2,208,280$12.7M0
AWM Investment Company, Inc.1,700,000$9.8Mnew
Soleus Capital Management, L.P.1,565,000$9M-285,000
Silvercrest Asset Management Group LLC1,428,470$8.2Mnew
Alta Wealth Advisors LLC1,409,160$8.1M0
Kennedy Capital Management LLC917,977$5.3M-9,823
Archon Capital Management LLC691,413$4M+250,000
Essex Investment Management Co LLC663,428$3.8M-29,381
Ensign Peak Advisors, Inc444,654$2.6M-300
Hodges Capital Management Inc.409,073$2.4M-26,763
Bank Pictet & Cie (Europe) AG255,200$1.5M0
Legato Capital Management LLC223,230$1.3M+6,889
1492 Capital Management LLC222,194$1.3M-3,557
Edmond DE Rothschild Holding S.A.200,004$1.2M-3,330

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

14 insiders reported holding 7,380,325 shares in total, about $58M at the last price.

HolderSharesAs of
Camblong JurgiExecutive Chairman, Director 3,387,150 October 12, 2026
Muken RossChief Executive Officer, Director 680,391 November 6, 2026
Xu ZhenyuChief Scientific Officer 541,493 October 13, 2026
Ossipow VincentDirector 522,860 June 18, 2026
Van Well DaanChief Legal Officer 332,716 October 5, 2026
Cox TroyDirector 328,743 June 18, 2026
Cardoza GeorgeChief Financial Officer 326,726 November 6, 2026
Hirsch DidierDirector 240,220 June 18, 2026
Cossery Jean-MichelDirector 206,212 June 18, 2026
Valente ManuelaChief People Officer 206,210 October 5, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about SOPH

What does SOPHiA GENETICS SA do?

SOPHiA GENETICS SA is a company in the Technology sector, listed on NASDAQ as SOPH. Its shares trade on NASDAQ under the ticker SOPH.

What is SOPHiA GENETICS SA's net worth?

SOPHiA GENETICS SA has a market value (market cap) of $669.1M at the latest share price, and shareholders' equity of $47.1M on its balance sheet at December 31, 2025. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is SOPHiA GENETICS SA profitable?

No. In fiscal 2025 it reported a net loss of $79M on revenue of $77.3M.

How much revenue does SOPHiA GENETICS SA make?

In fiscal 2025 SOPHiA GENETICS SA reported revenue of $77.3M. That is 18.6% more than a year earlier.

When did SOPHiA GENETICS SA last report?

Its most recent periodic report is the annual report (foreign issuer) (20-F) filed on March 3, 2026. It covers the period to December 31, 2025. Its newest filing of any kind is the planned insider sale from November 9, 2026.

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Where the numbers come from

Financial figures are the values SOPHiA GENETICS SA tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.