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NASDAQ · Health care

Revolution Medicines, Inc. (RVMD)

It posted a net loss of $1.8B. In fiscal 2025 capital spending exceeded operating cash flow by $913.7M. At June 30, 2026 it held $815.4M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 5, 2026.

Price
$207.68
+0.50% on the day · October 5, 2026
52-week range $45.80 to $224.31
Market cap
$44.5B

Key facts about Revolution Medicines, Inc.

Net worth
Revolution Medicines, Inc. has a market value (market cap) of $44.5B at the latest share price, and shareholders' equity of $2.6B on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $0, with a net loss of $1.1B.
Cash flow
In fiscal 2025 operations used $897.7M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on August 5, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR
Next earnings report
Revolution Medicines, Inc.'s next report is expected around November 4, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

What Revolution Medicines, Inc. does

Revolution Medicines is a clinical-stage oncology company that develops targeted therapies for cancer patients. The company focuses on developing small-molecule inhibitors that target the RAS pathway, a biochemical signalling pathway frequently mutated in difficult-to-treat cancers such as pancreatic, non-small cell lung, and colorectal cancers. Its shares trade on NASDAQ under the ticker RVMD.

Revenue and profit by year

Revenue
FY18: $20.2M $20.2M FY18FY20: $50M $50M FY20FY20: $43M $43M FY20FY21: $29.4M $29.4M FY21FY22: $35.4M $35.4M FY22FY23: $11.6M $11.6M FY23FY24: $0 $0 FY24FY25: $0 $0 FY25
Net income
FY18: -$41.8M -$41.8M FY18FY20: -$47.7M -$47.7M FY20FY20: -$108.2M -$108.2M FY20FY21: -$187.1M -$187.1M FY21FY22: -$248.7M -$248.7M FY22FY23: -$436.4M -$436.4M FY23FY24: -$600.1M -$600.1M FY24FY25: -$1.1B -$1.1B FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$0-$1.2B-$1.1B-$5.95-$913.7M
2024$0-$689.5M-$600.1M-$3.58-$567.7M
2023$11.6M-$487.2M-$436.4M-$3.86-$358.3M
2022$35.4M-$258.3M-$248.7M-$3.08-$235.2M
2021$29.4M-$188M-$187.1M-$2.57-$153.7M
2020$43M-$110.7M-$108.2M-$2.01-$103M

Full financial statements: income, balance sheet and cash flow

Next report expected around November 4, 2026.

Estimated from its filing rhythm: about 91 days after its last report of August 5, 2026, its usual gap. Not a date the company has announced. See the report calendar

Latest SEC filings

What Revolution Medicines, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. September 1, 2026
  2. August 26, 2026
  3. August 14, 2026
  4. August 13, 2026
  5. August 13, 2026
  6. August 5, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$3.06 versus -$1.31.
  7. August 5, 2026
  8. July 29, 2026
  9. June 22, 2026
  10. May 15, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 1, 2026. Insider transactions on SEC

Insider trades

What the people running Revolution Medicines, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $78M worth of shares in the last 90 days and bought none on the open market. All of the selling was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$78M
last 90 days
Net sold
380,710
$78M
DateInsiderWhatSharesPriceValueFiling
September 29, 2026 Sandler Alan B.Chief Development Officer Exercised options 6,000 $58.84 $353K Form 4
September 29, 2026 Sandler Alan B.Chief Development Officer Soldpre-planned (10b5-1) 2,200 $200.82 $441.8K Form 4
September 29, 2026 Sandler Alan B.Chief Development Officer Soldpre-planned (10b5-1) 1,609 $201.72 $324.6K Form 4
September 29, 2026 Sandler Alan B.Chief Development Officer Soldpre-planned (10b5-1) 1,000 $202.81 $202.8K Form 4
September 29, 2026 Sandler Alan B.Chief Development Officer Soldpre-planned (10b5-1) 1,199 $203.91 $244.5K Form 4
September 29, 2026 Sandler Alan B.Chief Development Officer Soldpre-planned (10b5-1) 301 $204.72 $61.6K Form 4
September 25, 2026 Cislini JeffSVP & General Counsel Soldpre-planned (10b5-1) 765 $207.32 $158.6K Form 4
September 25, 2026 Mancini AnthonySee Remarks Exercised options 3,121 $33.62 $104.9K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns RVMD

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Dapice Joshua J.13G, passive with 30 related filers 7.5% 14,596,149 February 9, 2026
Farallon Capital Management, L.L.C.13G, passive with 28 related filers 6.4% 13,564,149 August 13, 2026
Baker Bros. Advisors LP13G, passive with 3 related filers 5.3% 11,443,357 August 14, 2026
JANUS HENDERSON GROUP Ltd.13G, passive 5.1% 10,736,145 August 13, 2026
Fmr LLC13G, passive with 1 related filers 5% 9,401,687 November 5, 2025

Latest filings below 5%: The Vanguard Group 0% (March 27, 2026); Wellington Management Group LLP 3.6% (February 10, 2026).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 690 managers reported a position.

HolderSharesValueChange on quarter
BlackRock, Inc.13,695,790$2.56B+2,483,084
Farallon Capital Management, L.L.C.13,550,796$2.54B-54,000
Fmr LLC12,200,422$2.28B+3,736,108
Baker Bros. Advisors LP11,443,357$2.14B+1,888,000
Darwin Global Management, Ltd.10,629,822$2.05B+8,418,804
Jupiter Topco LLC10,736,145$2.01Bnew
Vanguard Capital Management LLC9,088,661$1.7B+726,377
Vanguard Portfolio Management LLC8,294,855$1.55B+792,232
Nextech Invest Ltd.7,601,087$1.42B0
Paradigm Biocapital Advisors LP6,361,323$1.19B-294,380
UBS Group AG5,448,364$1.02B+1,061,573
State Street Corp4,897,051$917.1M+494,389
Capital World Investors4,008,244$750.7Mnew
Geode Capital Management, LLC3,942,676$736.8M+604,534
Wellington Management Group Llp3,843,415$719.8M-2,184,404
Jpmorgan Chase & Co3,298,066$636.9M+2,996,673
Bvf Inc2,965,160$555.3M+108,378
Alphabet Inc.2,946,619$551.8M-345,906
Casdin Capital, LLC2,577,333$482.7M0
Deerfield Management Company, L.P.2,392,000$448M+95,000

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

16 insiders reported holding 3,821,752 shares in total, about $793.7M at the last price.

HolderSharesAs of
Borisy AlexisDirector 2,340,075 June 18, 2026
Goldsmith Mark ASee Remarks, Director 314,76661,424 held indirectly September 16, 2026
Kelsey Stephen MichaelSee Remarks 286,307 September 16, 2026
Horn Margaret AChief Operating Officer 149,680 September 16, 2026
Anders JackChief Financial Officer 119,216 September 16, 2026
Wang XiaolinSee Remarks 116,063 March 17, 2026
Wei LinChief Medical Officer 101,366 March 17, 2026
Horning SandraDirector 97,765 June 18, 2026
Kim Lorence H.Director 74,281 September 8, 2026
Sandler Alan B.Chief Development Officer 52,559 September 29, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about RVMD

What does Revolution Medicines, Inc. do?

Revolution Medicines is a clinical-stage oncology company that develops targeted therapies for cancer patients. The company focuses on developing small-molecule inhibitors that target the RAS pathway, a biochemical signalling pathway frequently mutated in difficult-to-treat cancers such as pancreatic, non-small cell lung, and colorectal cancers. Its shares trade on NASDAQ under the ticker RVMD.

What is Revolution Medicines, Inc.'s net worth?

Revolution Medicines, Inc. has a market value (market cap) of $44.5B at the latest share price, and shareholders' equity of $2.6B on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Revolution Medicines, Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $1.8B.

When did Revolution Medicines, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 5, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the insider trade from October 1, 2026.

When is Revolution Medicines, Inc.'s next earnings report?

Revolution Medicines, Inc.'s next report is expected around November 4, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Revolution Medicines, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.