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NASDAQ · Health care

uniQure N.V. (QURE)

uniQure N.V. brought in $20.2M of revenue over the twelve months to September 30, 2026, up 28.0% from a year earlier. It posted a net loss of $232.9M. In fiscal 2025 capital spending exceeded operating cash flow by $178.4M. At September 30, 2026 it held $98.4M in cash against $50.3M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 4, 2026.

Free, no password. An email when QURE files with the SEC.

Price
$23.03
+1.05% on the day · November 10, 2026
52-week range $8.73 to $51.72
Market cap
$1.6B
Revenue (last 12 months)
$20.2M
+28.0% year on year
Net margin
-1,154.8%

Key facts about uniQure N.V.

Net worth
uniQure N.V. has a market value (market cap) of $1.6B at the latest share price, and shareholders' equity of $294.7M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $16.1M (-40.6% year on year), with a net loss of $199M. Over the 12 months to September 30, 2026: revenue $20.2M, net loss $232.9M.
Cash flow
In fiscal 2025 operations used $178M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 4, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
uniQure N.V.'s next report is expected around March 1, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What uniQure N.V. does

uniQure N.V. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker QURE.

Revenue and profit by year

Revenue
FY18: $11.3M $11.3M FY18FY19: $7.3M $7.3M FY19FY20: $37.5M $37.5M FY20FY21: $524M $524M FY21FY22: $106.5M $106.5M FY22FY23: $15.8M $15.8M FY23FY24: $27.1M $27.1M FY24FY25: $16.1M $16.1M FY25
Net income
FY18: -$83.3M -$83.3M FY18FY19: -$124.2M -$124.2M FY19FY20: -$125M -$125M FY20FY21: $329.6M $329.6M FY21FY22: -$126.8M -$126.8M FY22FY23: -$308.5M -$308.5M FY23FY24: -$239.6M -$239.6M FY24FY25: -$199M -$199M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$16.1M-$185.3M-$199M-$3.46-$178.4M
2024$27.1M-$184.3M-$239.6M-$4.92-$186.1M
2023$15.8M-$282.9M-$308.5M-$6.47-$153.1M
2022$106.5M-$143.2M-$126.8M-$2.71-$162.7M
2021$524M$310.6M$329.6M$7.04$270.5M
2020$37.5M-$125.4M-$125M-$2.81-$142.1M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around March 1, 2027.

Estimated from its filing rhythm: 52 weeks after its report of March 2, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where QURE ranks in Health care

Revenue$16.1M
#490 of 751 in Health care · Bottom 35%
Revenue growth-40.6%
#516 of 532 in Health care · Bottom 3%
Net margin-1,236.0%
#538 of 544 in Health care · Bottom 1%
Free cash flow margin-1,108.2%
#486 of 490 in Health care · Bottom 1%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What uniQure N.V. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 4, 2026
    Quarterly report 10-Q · period to September 30, 2026Revenue rose 40% to $5.2M versus the same quarter last year; diluted EPS -$0.88 versus -$1.38.
  2. November 4, 2026
  3. November 2, 2026
  4. September 29, 2026
  5. September 2, 2026
  6. August 14, 2026
  7. August 14, 2026
  8. July 29, 2026
  9. July 29, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue rose 11% to $5.8M versus the same quarter last year; diluted EPS -$1.22 versus -$0.69.
  10. July 29, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on November 6, 2026. Insider transactions on SEC

Insider trades

What the people running uniQure N.V. did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider bought or sold shares on the open market in the last 90 days. The 1 reported changes were pay in shares, option exercises, shares withheld for tax or gifts.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days
DateInsiderWhatSharesPriceValueFiling
October 30, 2026 Abi-Saab WalidChief Medical Officer Received as pay 18,750 - - Form 4
July 2, 2026 Kapusta Matthew CCEO, Managing Director, Director Exercised options 21,082 $19.39 $408.8K Form 4
July 2, 2026 Kapusta Matthew CCEO, Managing Director, Director Soldpre-planned (10b5-1) 9,200 $44.43 $408.8K Form 4
July 2, 2026 Kapusta Matthew CCEO, Managing Director, Director Soldpre-planned (10b5-1) 4,282 $45.43 $194.5K Form 4
July 2, 2026 Kapusta Matthew CCEO, Managing Director, Director Soldpre-planned (10b5-1) 7,600 $45.89 $348.8K Form 4
June 30, 2026 Kaye JackDirector Exercised options 4,107 $37.00 $152K Form 4
June 30, 2026 Kaye JackDirector Soldpre-planned (10b5-1) 4,107 $46.49 $190.9K Form 4
June 30, 2026 Kaye JackDirector Exercised options 17,060 $20.18 $344.3K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns QURE

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Avoro Capital Advisors LLC13G, passive with 1 related filers 9.87% 6,150,000 February 17, 2026
RTW Investments, LP13G, passive with 1 related filers 5.7% 3,941,572 August 14, 2026

Latest filings below 5%: G1 Execution Services, LLC 4.8% (August 14, 2026); Aberdeen Group plc 4.52% (July 20, 2026); Fmr LLC 2.8% (May 6, 2026); EcoR1 Capital, LLC 0% (February 17, 2026); Vestal Point Capital, LP 0.4% (November 14, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 254 managers reported a position.

HolderSharesValueChange on quarter
Avoro Capital Advisors LLC6,727,777$309.9M+768,182
Jpmorgan Chase & Co4,867,755$230.8M+2,030,289
Rtw Investments, LP3,941,572$181.5M+1,355,216
State Street Corp2,903,825$133.8M+643,313
Aberdeen Group plc2,848,117$131.2M-2,458,269
BlackRock, Inc.1,877,453$86.5M+143,995
Orbimed Advisors LLC1,807,486$83.3M-328,663
Jane Street Group, LLC1,610,483$74.2M+974,488
Jennison Associates LLC1,561,412$71.9M+327,623
Boxer Capital Management, LLC1,503,300$69.2M+841,300
Goldman Sachs Group Inc1,475,956$68M+212,720
Two Sigma Investments, LP1,462,024$67.3M-1,213,847
Two Seas Capital LP1,441,410$66.4M+141,410
Fmr LLC1,270,068$58.5M-473,740
Mak Capital One LLC1,232,051$56.7M+790,846
Mpm Bioimpact LLC1,225,855$56.5M-143,376
Morgan Stanley1,066,639$49.1M+700,522
Assenagon Asset Management S.A.1,027,060$47.3M+880,311
Vestal Point Capital, LP935,000$43.1M+576,004
Maverick Capital Ltd925,383$42.6M+227,743

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

12 insiders reported holding 1,408,807 shares in total, about $32.4M at the last price.

HolderSharesAs of
Kapusta Matthew CCEO, Managing Director, Director 519,227 July 2, 2026
Klemt ChristianChief Financial Officer 226,581 March 4, 2026
Abi-Saab WalidChief Medical Officer 166,985 October 30, 2026
Potts JeannetteChief Legal Officer 133,246 June 15, 2026
O'Keefe KylieChief Customer & Strat Officer 108,864 June 11, 2026
Balachandran MadhavanDirector 43,254 June 17, 2026
Springhorn Jeremy P.Director 43,251 June 11, 2026
Meek David D.Director 39,747 June 11, 2026
Post Leonard EDirector 35,494 June 11, 2026
Jacques Rachelle SuzanneDirector 33,903 June 11, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about QURE

What does uniQure N.V. do?

uniQure N.V. is a company in the Health care sector, listed on NASDAQ as QURE. Its shares trade on NASDAQ under the ticker QURE.

What is uniQure N.V.'s net worth?

uniQure N.V. has a market value (market cap) of $1.6B at the latest share price, and shareholders' equity of $294.7M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is uniQure N.V. profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $232.9M on revenue of $20.2M.

How much revenue does uniQure N.V. make?

Over the twelve months to September 30, 2026 uniQure N.V. reported revenue of $20.2M. That is 28.0% more than a year earlier.

When did uniQure N.V. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 4, 2026. It covers the period to September 30, 2026. Its newest filing of any kind is the planned insider sale from November 6, 2026.

When is uniQure N.V.'s next earnings report?

uniQure N.V.'s next report is expected around March 1, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values uniQure N.V. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.