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Ptc Therapeutics, Inc. (PTCT)

Ptc Therapeutics, Inc. brought in $1.2B of revenue over the twelve months to September 30, 2026, down 35.1% from a year earlier. It posted a net loss of $106M. Operating cash flow minus capital spending left $702.3M of free cash flow in fiscal 2025. At September 30, 2026 it held $508.9M in cash against $536.3M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on October 29, 2026.

Free, no password. An email when PTCT files with the SEC.

Price
$64.14
-1.37% on the day · November 10, 2026
52-week range $58.80 to $90.87
Market cap
$5.4B
Revenue (last 12 months)
$1.2B
-35.1% year on year
Net margin
-9.2%
P/E
8.2
on FY2025 diluted EPS

Key facts about Ptc Therapeutics, Inc.

Net worth
Ptc Therapeutics, Inc. has a market value (market cap) of $5.4B at the latest share price, and shareholders' equity of -$191.2M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $1.7B (+114.5% year on year), with net income of $682.6M. Over the 12 months to September 30, 2026: revenue $1.2B, net loss $106M.
Cash flow
In fiscal 2025 operations brought in $711.2M of cash; after $8.9M of capital spending, free cash flow was $702.3M.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on October 29, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Ptc Therapeutics, Inc.'s next report is expected around January 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Ptc Therapeutics, Inc. does

Ptc Therapeutics, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker PTCT.

Revenue and profit by year

Revenue
FY18: $264.7M $264.7M FY18FY19: $307M $307M FY19FY20: $380.8M $380.8M FY20FY21: $538.6M $538.6M FY21FY22: $698.8M $698.8M FY22FY23: $937.8M $937.8M FY23FY24: $806.8M $806.8M FY24FY25: $1.7B $1.7B FY25
Net income
FY18: -$128.1M -$128.1M FY18FY19: -$251.6M -$251.6M FY19FY20: -$438.2M -$438.2M FY20FY21: -$523.9M -$523.9M FY21FY22: -$559M -$559M FY22FY23: -$626.6M -$626.6M FY23FY24: -$363.3M -$363.3M FY24FY25: $682.6M $682.6M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$1.7B$866.9M$682.6M$7.78$702.3M
2024$806.8M-$302.6M-$363.3M-$4.73-$114.2M
2023$937.8M-$439.5M-$626.6M-$8.37-$186.9M
2022$698.8M-$447.4M-$559M-$7.79-$388.7M
2021$538.6M-$374.4M-$523.9M-$7.43-$279.5M
2020$380.8M-$431.8M-$438.2M-$6.64-$211.9M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around January 11, 2027.

Estimated from its filing rhythm: 52 weeks after its report of January 12, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where PTCT ranks in Health care

Revenue$1.7B
#123 of 751 in Health care · Top 16%
Revenue growth+114.5%
#46 of 532 in Health care · Top 8%
Net margin39.4%
#20 of 544 in Health care · Top 3%
Free cash flow margin40.6%
#13 of 490 in Health care · Top 2%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Ptc Therapeutics, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 3, 2026
  2. October 29, 2026
    Quarterly report 10-Q · period to September 30, 2026Revenue rose 70% to $357.8M versus the same quarter last year; diluted EPS -$0.62 versus $0.20.
  3. October 29, 2026
  4. September 21, 2026
  5. August 28, 2026
  6. August 13, 2026
  7. July 30, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue rose 102% to $360.5M versus the same quarter last year; diluted EPS $0.92 versus -$0.83.
  8. July 30, 2026
  9. June 18, 2026
  10. June 16, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 16, 2026. Insider transactions on SEC

What is PTCT worth? A DCF from its reported cash flow

Insider trades

What the people running Ptc Therapeutics, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $7.8M worth of shares in the last 90 days and bought none on the open market. All of the selling was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$7.8M
last 90 days
Net sold
112,078
$7.8M
DateInsiderWhatSharesPriceValueFiling
October 14, 2026 Schmertzler MichaelDirector Soldpre-planned (10b5-1), indirect 2,118 $59.52 $126.1K Form 4
October 14, 2026 Schmertzler MichaelDirector Soldpre-planned (10b5-1), indirect 382 $60.14 $23K Form 4
October 9, 2026 Boulding Mark ElliottEXEC. VP AND CLO Exercised options 192 $39.42 $7.6K Form 4
October 9, 2026 Boulding Mark ElliottEXEC. VP AND CLO Soldpre-planned (10b5-1) 192 $64.26 $12.3K Form 4
October 7, 2026 Schmertzler MichaelDirector Soldpre-planned (10b5-1), indirect 2,447 $63.38 $155.1K Form 4
October 7, 2026 Schmertzler MichaelDirector Soldpre-planned (10b5-1), indirect 53 $63.95 $3.4K Form 4
October 6, 2026 Boulding Mark ElliottEXEC. VP AND CLO Exercised options 435 $39.42 $17.1K Form 4
October 6, 2026 Boulding Mark ElliottEXEC. VP AND CLO Soldpre-planned (10b5-1) 435 $64.16 $27.9K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns PTCT

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Janus Henderson Group PLC13G, passive 8.7% 7,193,433 May 15, 2026
Vanguard Portfolio Management13G, passive 5.88% 4,871,329 April 29, 2026
Vanguard Capital Management13G, passive 5.17% 4,284,448 April 30, 2026

Latest filings below 5%: The Vanguard Group 0% (March 27, 2026); Wellington Management Group LLP 4.8% (February 10, 2026); Armistice Capital, LLC 4.08% (November 14, 2025); Camber Capital Management LP 4.15% (February 14, 2025); PTC Therapeutics, Inc. 3.24% (August 27, 2024).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 382 managers reported a position.

HolderSharesValueChange on quarter
BlackRock, Inc.13,964,554$1.14B+1,015,837
Rtw Investments, LP7,746,415$631.9M0
Jupiter Topco LLC7,236,402$590.2Mnew
Vanguard Portfolio Management LLC4,928,111$402M+123,517
State Street Corp4,598,952$375.1M+252,433
Wellington Management Group Llp4,128,273$336.7M+185,663
Vanguard Capital Management LLC3,739,127$305M+62,871
Geode Capital Management, LLC2,207,376$180.1M-2,578
Toronto Dominion Bank2,165,846$176.7M-860,117
Westfield Capital Management Co LP1,956,156$159.6Mnew
Hood River Capital Management LLC1,738,613$141.8M+74,054
William Blair Investment Management, LLC1,722,688$140.5Mnew
D. E. Shaw & Co., Inc.1,548,919$126.3M-91,462
Tang Capital Management LLC1,500,000$122.4M0
Bank of America Corp1,452,277$118.5M-434,564
Driehaus Capital Management LLC1,440,107$117.5M+424,335
Fmr LLC1,398,261$114.1M-130,101
Jefferies Financial Group Inc.1,357,042$110.7M+2,583
Fuller & Thaler Asset Management, Inc.1,156,819$94.4Mnew
Pictet Asset Management Holding SA1,147,844$93.6M-35,876

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

18 insiders reported holding 2,522,453 shares in total, about $161.8M at the last price.

HolderSharesAs of
Schmertzler MichaelDirector 1,454,8601,291,594 held indirectly October 14, 2026
Klein Matthew B.CHIEF EXECUTIVE OFFICER, Director 383,868 August 4, 2026
Boulding Mark ElliottEXEC. VP AND CLO 105,272 October 9, 2026
Gravier PierreCHIEF FINANCIAL OFFICER 83,986 July 14, 2026
Golden Lee ScottEVP & CHIEF MEDICAL OFFICER 79,115 April 2, 2026
Pauwels EricCHIEF BUSINESS OFFICER 73,411 June 10, 2026
Utter Christine MarieSVP, CHIEF ACCOUNTING OFFICER 70,199 June 17, 2026
Almstead Neil GregoryCHIEF TECHNICAL OPS OFFICER 63,0362,737 held indirectly July 9, 2026
Sollie-Zetlmayer Hege ElisabethDirector 52,526 July 28, 2026
Steele Glenn Jr Md PhdDirector 22,500 September 30, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about PTCT

What does Ptc Therapeutics, Inc. do?

Ptc Therapeutics, Inc. is a company in the Health care sector, listed on NASDAQ as PTCT. Its shares trade on NASDAQ under the ticker PTCT.

What is Ptc Therapeutics, Inc.'s net worth?

Ptc Therapeutics, Inc. has a market value (market cap) of $5.4B at the latest share price, and shareholders' equity of -$191.2M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Ptc Therapeutics, Inc. profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $106M on revenue of $1.2B.

How much revenue does Ptc Therapeutics, Inc. make?

Over the twelve months to September 30, 2026 Ptc Therapeutics, Inc. reported revenue of $1.2B. That is 35.1% less than a year earlier.

When did Ptc Therapeutics, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on October 29, 2026. It covers the period to September 30, 2026. Its newest filing of any kind is the investor disclosure from November 3, 2026.

When is Ptc Therapeutics, Inc.'s next earnings report?

Ptc Therapeutics, Inc.'s next report is expected around January 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Ptc Therapeutics, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.