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NASDAQ · Health care

Pliant Therapeutics, Inc. (PLRX)

It posted a net loss of $92.3M. In fiscal 2025 capital spending exceeded operating cash flow by $128.7M. At June 30, 2026 it held $24.9M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 11, 2026.

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Price
$0.80
-1.25% on the day · November 9, 2026
52-week range $0.79 to $1.82
Market cap
$49.5M

Key facts about Pliant Therapeutics, Inc.

Net worth
Pliant Therapeutics, Inc. has a market value (market cap) of $49.5M at the latest share price, and shareholders' equity of $146.9M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $0, with a net loss of $149.3M.
Cash flow
In fiscal 2025 operations used $128.3M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on August 11, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR
Next earnings report
Pliant Therapeutics, Inc.'s next report is expected around November 23, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

What Pliant Therapeutics, Inc. does

Pliant Therapeutics, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker PLRX.

Revenue and profit by year

Revenue
FY20: $57.1M $57.1M FY20FY20: $41.8M $41.8M FY20FY21: $7.6M $7.6M FY21FY22: $9.7M $9.7M FY22FY23: $1.6M $1.6M FY23FY24: $0 $0 FY24FY25: $0 $0 FY25
Net income
FY20: -$631K -$631K FY20FY20: -$41.5M -$41.5M FY20FY21: -$97.3M -$97.3M FY21FY22: -$123.3M -$123.3M FY22FY23: -$161.3M -$161.3M FY23FY24: -$210.3M -$210.3M FY24FY25: -$149.3M -$149.3M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$0-$156.4M-$149.3M-$2.43-$128.7M
2024$0-$228.4M-$210.3M-$3.47-$159.4M
2023$1.6M-$184.1M-$161.3M-$2.75-$117.3M
2022$9.7M-$127.2M-$123.3M-$2.94-$96.4M
2021$7.6M-$97.5M-$97.3M-$2.71-$77.4M
2020$41.8M-$41.6M-$41.5M-$1.95-$38.8M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around November 23, 2026.

Estimated from its filing rhythm: about 104 days after its last report of August 11, 2026, its usual gap. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Latest SEC filings

What Pliant Therapeutics, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. August 14, 2026
  2. August 14, 2026
  3. August 11, 2026
  4. August 11, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$0.36 versus -$0.71.
  5. July 13, 2026
  6. June 11, 2026
  7. May 11, 2026
    Quarterly report 10-Q · period to March 31, 2026Diluted EPS -$0.32 versus -$0.92.
  8. May 11, 2026
  9. April 22, 2026
  10. April 22, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 2, 2026. Insider transactions on SEC

Insider trades

What the people running Pliant Therapeutics, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider trades were reported in the last 90 days.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days
DateInsiderWhatSharesPriceValueFiling
January 20, 2026 Kuo MinnieChief Operating Officer Soldpre-planned (10b5-1) 6,917 $1.28 $8.9K Form 4
January 20, 2026 Coulie BernardPresident and CEO, Director Soldpre-planned (10b5-1) 89,375 $1.28 $114.4K Form 4
January 20, 2026 Cheung LilyChief Human Resource Officer Soldpre-planned (10b5-1) 7,534 $1.28 $9.6K Form 4
January 20, 2026 Cummings Keith LamontChief Financial Officer Soldpre-planned (10b5-1) 24,002 $1.28 $30.7K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns PLRX

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Tang Capital Management, LLC13D, may seek influence with 6 related filers 9.6% 5,859,044 March 10, 2025
ADAR1 Capital Management, LLC13G, passive with 1 related filers 8.9% 5,509,724 August 14, 2026

Latest filings below 5%: Kenneth Griffin 3.5% (August 14, 2026); Point72 Asset Management, L.P. 0.1% (February 17, 2026); Woodline Partners LP 3.3% (February 17, 2026); Deep Track Capital, LP 0% (November 14, 2025); The Vanguard Group 4.89% (July 29, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 86 managers reported a position.

HolderSharesValueChange on quarter
Tang Capital Management LLC6,141,261$7M-1,871
ADAR1 Capital Management, LLC5,509,724$6.3M+2,924,598
Vanguard Capital Management LLC2,440,351$2.8M+97,250
Two Sigma Investments, LP2,262,832$2.6M+9,694
Citadel Advisors LLC2,142,226$2.4M-1,084,373
Renaissance Technologies LLC2,049,874$2.3M+197,032
Monaco Asset Management SAM1,938,747$2.2M0
Lynx1 Capital Management LP1,798,070$2Mnew
BML Capital Management, LLC1,546,137$1.8M0
Prosight Management, LP1,370,233$1.6M-297,367
Peapod Lane Capital LLC1,309,013$1.5M+20,435
Woodline Partners LP1,296,534$1.5M-370,296
BlackRock, Inc.1,151,214$1.3M+54,784
Ikarian Capital, LLC1,000,000$1.1Mnew
Eversept Partners, LP891,425$1M0
Marshall Wace, Llp835,124$952K-160,849
Redmile Group, LLC772,126$880.2K0
Jpmorgan Chase & Co681,647$783.9K-180,176
Jacobs Levy Equity Management, Inc643,120$733.2K-75,423
Geode Capital Management, LLC578,577$660K+161,303

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

4 insiders reported holding 885,468 shares in total, about $708K at the last price.

HolderSharesAs of
Coulie BernardPresident and CEO, Director 505,601 January 20, 2026
Cummings Keith LamontChief Financial Officer 297,214 January 20, 2026
Cheung LilyChief Human Resource Officer 44,847 January 20, 2026
Kuo MinnieChief Operating Officer 37,806 January 20, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about PLRX

What does Pliant Therapeutics, Inc. do?

Pliant Therapeutics, Inc. is a company in the Health care sector, listed on NASDAQ as PLRX. Its shares trade on NASDAQ under the ticker PLRX.

What is Pliant Therapeutics, Inc.'s net worth?

Pliant Therapeutics, Inc. has a market value (market cap) of $49.5M at the latest share price, and shareholders' equity of $146.9M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Pliant Therapeutics, Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $92.3M.

When did Pliant Therapeutics, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 11, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the insider trade from October 2, 2026.

When is Pliant Therapeutics, Inc.'s next earnings report?

Pliant Therapeutics, Inc.'s next report is expected around November 23, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Pliant Therapeutics, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.