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NASDAQ · Health care

NuCana plc (NCNA)

It posted a net loss of £29.4M. In fiscal 2025 capital spending exceeded operating cash flow by £7.5M. At December 31, 2025 it held £24.3M in cash. Its latest periodic report to the SEC is the annual report (foreign issuer) (20-F) filed on March 19, 2026.

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Price
$0.96
-0.01% on the day · November 10, 2026
52-week range $0.90 to $4.55
Market cap
$4M

Key facts about NuCana plc

Net worth
NuCana plc has a market value (market cap) of $4M at the latest share price, and shareholders' equity of £24.3M on its balance sheet at December 31, 2025. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Cash flow
In fiscal 2025 operations used £7.5M of cash.
Latest report
The latest periodic report (annual report (foreign issuer), 20-F) was filed with the SEC on March 19, 2026 and covers the period to December 31, 2025. Open on SEC EDGAR

What NuCana plc does

NuCana plc is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker NCNA.

Revenue and profit by year

Net income
FY18: -£13.8M -£13.8M FY18FY19: -£21.4M -£21.4M FY19FY20: -£30.7M -£30.7M FY20FY21: -£40.5M -£40.5M FY21FY22: -£32M -£32M FY22FY23: -£27.6M -£27.6M FY23FY24: -£19M -£19M FY24FY25: -£29.4M -£29.4M FY25

Fiscal years as reported in annual reports. Amounts in GBP.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025n/a-£20.1M-£29.4M£0.00-£7.5M
2024n/a-£22.8M-£19M-£0.26-£19.1M
2023n/a-£32.8M-£27.6M-£0.53-£26.4M
2022n/a-£39.1M-£32M-£0.61-£23.2M
2021n/a-£47.9M-£40.5M-£0.78-£23.9M
2020n/a-£36.4M-£30.7M-£0.81-£22M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Latest SEC filings

What NuCana plc has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. September 30, 2026
  2. August 13, 2026
  3. June 8, 2026
  4. June 1, 2026
  5. May 14, 2026
  6. May 6, 2026
  7. March 19, 2026
  8. March 19, 2026
    Annual report (foreign issuer) 20-F · period to December 31, 2025Diluted EPS £0.00 versus -£0.26.
  9. March 19, 2026
  10. March 18, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on June 24, 2026. Insider transactions on SEC

Insider trades

What the people running NuCana plc did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider trades were reported in the last 90 days.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns NCNA

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Hugh S. Griffith13D, may seek influence 12% 2,829,961,890 March 18, 2026
Dr. James I. Healy ("Healy")13D, may seek influence with 6 related filers 11.9% 6,283,392 February 27, 2024
Sofinnova Capital VI FCPR13D, may seek influence with 7 related filers 5.1% 4,987,975 February 14, 2025

Latest filings below 5%: Dr. James I. Healy 0.1% (February 25, 2025).

Largest institutional holders

No Form 13F positions imported for this company yet.

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

No insider reported holdings on a Form 4 in the last 12 months.

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about NCNA

What does NuCana plc do?

NuCana plc is a company in the Health care sector, listed on NASDAQ as NCNA. Its shares trade on NASDAQ under the ticker NCNA.

What is NuCana plc's net worth?

NuCana plc has a market value (market cap) of $4M at the latest share price, and shareholders' equity of £24.3M on its balance sheet at December 31, 2025. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is NuCana plc profitable?

No. In fiscal 2025 it reported a net loss of £29.4M.

When did NuCana plc last report?

Its most recent periodic report is the annual report (foreign issuer) (20-F) filed on March 19, 2026. It covers the period to December 31, 2025. Its newest filing of any kind is the foreign issuer update from September 30, 2026.

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Where the numbers come from

Financial figures are the values NuCana plc tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.