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Lyell Immunopharma, Inc. (LYEL)

Lyell Immunopharma, Inc. brought in $27K of revenue over the twelve months to June 30, 2026, down 55.0% from a year earlier. It posted a net loss of $248.5M. In fiscal 2025 capital spending exceeded operating cash flow by $150.8M. At June 30, 2026 it held $73M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 6, 2026.

Price
$9.85
-2.67% on the day · September 25, 2026
52-week range $9.81 to $45.00
Market cap
$241.4M
Revenue (last 12 months)
$27K
-55.0% year on year
Net margin
-920,285.2%

What Lyell Immunopharma, Inc. does

Lyell Immunopharma, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker LYEL.

Revenue and profit by year

Revenue
FY19: $657K $657K FY19FY21: $7.8M $7.8M FY21FY21: $10.7M $10.7M FY21FY22: $84.7M $84.7M FY22FY23: $130K $130K FY23FY24: $61K $61K FY24FY25: $36K $36K FY25
Net income
FY19: -$129.4M -$129.4M FY19FY21: -$204.5M -$204.5M FY21FY21: -$250.2M -$250.2M FY21FY22: -$183.1M -$183.1M FY22FY23: -$234.6M -$234.6M FY23FY24: -$343M -$343M FY24FY25: -$274.4M -$274.4M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$36K-$269.4M-$274.4M-$16.06-$150.8M
2024$61K-$358.8M-$343M-$26.23-$162.9M
2023$130K-$247M-$234.6M-$18.70-$166.4M
2022$84.7M-$187.1M-$183.1M-$14.88-$193.8M
2021$10.7M-$214.8M-$250.2M-$37.00-$191.8M
2021$7.8M-$211.9M-$204.5M-$315.49-$212.4M
Next report expected around November 11, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 12, 2025. Not a date the company has announced. See the report calendar

Where LYEL ranks in Health care

Revenue$36K
#520 of 523 in Health care · Bottom 1%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Lyell Immunopharma, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. September 10, 2026
  2. August 14, 2026
  3. August 6, 2026
    Quarterly report 10-Q · period to June 30, 2026
  4. August 6, 2026
  5. July 13, 2026
  6. June 18, 2026
  7. June 15, 2026
  8. May 15, 2026
  9. May 11, 2026
  10. May 8, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on September 10, 2026. Insider transactions on SEC

Insider trades

What the people running Lyell Immunopharma, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $193.4K worth of shares in the last 90 days and bought none on the open market.

Bought (open market)
$0
last 90 days
Sold
$193.4K
last 90 days
Net sold
12,535
$193.4K
DateInsiderWhatSharesPriceValueFiling
September 10, 2026 Shook DavidChief Medical Officer Sold 500 $12.70 $6.4K Form 4
August 21, 2026 Seely LynnPresident and CEO, Director Sold 9,589 $15.54 $149K Form 4
August 21, 2026 Hill Stephen J.Chief Operating Officer Sold 989 $15.54 $15.4K Form 4
August 21, 2026 Lee Gary K.Chief Scientific Officer Sold 1,457 $15.54 $22.6K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

All filings on SEC EDGAR

Questions about LYEL

What does Lyell Immunopharma, Inc. do?

Lyell Immunopharma, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker LYEL.

Is Lyell Immunopharma, Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $248.5M on revenue of $27K.

How much revenue does Lyell Immunopharma, Inc. make?

Over the twelve months to June 30, 2026 Lyell Immunopharma, Inc. reported revenue of $27K. That is 55.0% less than a year earlier.

When did Lyell Immunopharma, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 6, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the other event from September 10, 2026.

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Where the numbers come from

Financial figures are the values Lyell Immunopharma, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.