Invesaro

Stocks Health care INSM

NASDAQ · Health care

INSMED Inc (INSM)

INSMED Inc brought in $1.5B of revenue over the twelve months to September 30, 2026, up 240.0% from a year earlier. It posted a net loss of $605.6M. In fiscal 2025 capital spending exceeded operating cash flow by $967.6M. At September 30, 2026 it held $396.6M in cash against $546.8M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on October 29, 2026.

Free, no password. An email when INSM files with the SEC.

Price
$117.92
+1.56% on the day · November 10, 2026
52-week range $90.39 to $212.75
Market cap
$25.8B
Revenue (last 12 months)
$1.5B
+240.0% year on year
Net margin
-39.9%

Key facts about INSMED Inc

Net worth
INSMED Inc has a market value (market cap) of $25.8B at the latest share price, and shareholders' equity of $726.2M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $606.4M (+66.7% year on year), with a net loss of $1.3B. Over the 12 months to September 30, 2026: revenue $1.5B, net loss $605.6M.
Cash flow
In fiscal 2025 operations used $935M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on October 29, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
INSMED Inc's next report is expected around February 18, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What INSMED Inc does

INSMED Inc is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker INSM.

Revenue and profit by year

Revenue
FY18: $9.8M $9.8M FY18FY19: $136.5M $136.5M FY19FY20: $164.4M $164.4M FY20FY21: $188.5M $188.5M FY21FY22: $245.4M $245.4M FY22FY23: $305.2M $305.2M FY23FY24: $363.7M $363.7M FY24FY25: $606.4M $606.4M FY25
Net income
FY18: -$324.3M -$324.3M FY18FY19: -$254.3M -$254.3M FY19FY20: -$294.1M -$294.1M FY20FY21: -$434.7M -$434.7M FY21FY22: -$481.5M -$481.5M FY22FY23: -$749.6M -$749.6M FY23FY24: -$913.8M -$913.8M FY24FY25: -$1.3B -$1.3B FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$606.4M-$1.2B-$1.3B-$6.42-$967.6M
2024$363.7M-$878.3M-$913.8M-$5.57-$705.8M
2023$305.2M-$709.6M-$749.6M-$5.34-$549.5M
2022$245.4M-$457.3M-$481.5M-$3.91-$410.3M
2021$188.5M-$375.1M-$434.7M-$3.88-$370.6M
2020$164.4M-$265.2M-$294.1M-$3.01-$225.6M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around February 18, 2027.

Estimated from its filing rhythm: 52 weeks after its report of February 19, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where INSM ranks in Health care

Revenue$606.4M
#191 of 751 in Health care · Top 25%
Revenue growth+66.7%
#68 of 532 in Health care · Top 13%
Net margin-210.5%
#483 of 544 in Health care · Bottom 11%
Free cash flow margin-159.6%
#430 of 490 in Health care · Bottom 12%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What INSMED Inc has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. October 29, 2026
  2. October 29, 2026
    Quarterly report 10-Q · period to September 30, 2026Revenue rose 268% to $524.4M versus the same quarter last year; diluted EPS -$0.46 versus -$1.75.
  3. October 20, 2026
  4. October 5, 2026
    Executive or director change8-KInsmed Chief Financial Officer Sara Bonstein will step down effective October 30, 2026, while the company reaffirmed its full-year 2026 financial guidance.
  5. August 14, 2026
  6. August 6, 2026
  7. August 6, 2026
  8. August 6, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue rose 296% to $425.5M versus the same quarter last year; diluted EPS -$0.06 versus -$1.70.
  9. July 22, 2026
  10. July 16, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on November 3, 2026. Insider transactions on SEC

Insider trades

What the people running INSMED Inc did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $3.7M worth of shares in the last 90 days and bought none on the open market.

Bought (open market)
$0
last 90 days
Sold
$3.7M
last 90 days
Net sold
30,000
$3.7M
DateInsiderWhatSharesPriceValueFiling
October 19, 2026 Koppikar UtpalDirector Received as pay 6,139 - - Form 4
October 19, 2026 Hudson PaulDirector Received as pay 6,139 - - Form 4
September 9, 2026 Brennan David RDirector Sold 25,000 $124.00 $3.1M Form 4
August 17, 2026 Sharoky Melvin MdDirector Soldindirect 5,000 $127.53 $637.7K Form 4
August 10, 2026 Adsett RogerChief Operating Officer Exercised options 82,280 $13.67 $1.1M Form 4
August 10, 2026 Adsett RogerChief Operating Officer Exercised options 76,600 $17.16 $1.3M Form 4
August 10, 2026 Adsett RogerChief Operating Officer Exercised options 80,970 $30.46 $2.5M Form 4
August 10, 2026 Adsett RogerChief Operating Officer Sold 239,850 $133.27 $32M Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns INSM

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Fmr LLC13G, passive with 1 related filers 7.4% 16,127,583 August 6, 2026
Vanguard Capital Management13G, passive 5.34% 11,514,893 April 30, 2026

Latest filings below 5%: Darwin Global Management, Ltd. 3% (August 14, 2026); The Vanguard Group 0% (March 27, 2026); T. Rowe Price Associates, Inc. 3.3% (November 14, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 665 managers reported a position.

HolderSharesValueChange on quarter
Fmr LLC16,143,583$1.72B+2,983,416
BlackRock, Inc.15,807,984$1.69B-870,162
Vanguard Portfolio Management LLC10,407,962$1.11B+36,160
Jpmorgan Chase & Co10,428,170$1.09B-13,722,329
Vanguard Capital Management LLC9,790,865$1.04B+148,734
Baker Bros. Advisors LP8,796,111$937.8M+1,375,000
Capital International Investors8,238,124$878.3M+2,642,930
Darwin Global Management, Ltd.6,431,163$673.6M-10,374,021
Ameriprise Financial Inc6,179,571$658.9M+3,121,853
Orbis Allan Gray Ltd6,076,487$647.9M+4,203,663
State Street Corp6,052,174$645.3M+500,475
D. E. Shaw & Co., Inc.5,877,959$626.7M+252,134
Artisan Partners Limited Partnership5,441,718$580.2M-1,085,583
Rtw Investments, LP4,842,880$516.3M0
Geode Capital Management, LLC4,220,155$448.8M-230,234
Norges Bank3,377,641$360.1Mnew
Jupiter Topco LLC2,605,181$277.8Mnew
UBS Group AG2,584,446$275.6M+846,965
Citadel Advisors LLC2,556,973$272.6M+374,402
Franklin Resources Inc2,273,222$242.4M-344,029

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

16 insiders reported holding 1,226,373 shares in total, about $144.6M at the last price.

HolderSharesAs of
Lewis WilliamChair and CEO, Director 259,058 July 23, 2026
Sharoky Melvin MdDirector 246,081 August 17, 2026
Adsett RogerChief Operating Officer 98,744 August 10, 2026
Mcgirr David W JDirector 97,72353,400 held indirectly February 9, 2026
Desjardins ClarissaDirector 70,312 May 13, 2026
Bonstein SaraChief Financial Officer 69,082 June 3, 2026
Schafer CarolDirector 66,622 May 13, 2026
Anderson Elizabeth MDirector 62,034 May 13, 2026
Flammer Martina M.D.Chief Medical Officer 60,486 August 6, 2026
Lee LeoDirector 57,971 May 13, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about INSM

What does INSMED Inc do?

INSMED Inc is a company in the Health care sector, listed on NASDAQ as INSM. Its shares trade on NASDAQ under the ticker INSM.

What is INSMED Inc's net worth?

INSMED Inc has a market value (market cap) of $25.8B at the latest share price, and shareholders' equity of $726.2M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is INSMED Inc profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $605.6M on revenue of $1.5B.

How much revenue does INSMED Inc make?

Over the twelve months to September 30, 2026 INSMED Inc reported revenue of $1.5B. That is 240.0% more than a year earlier.

When did INSMED Inc last report?

Its most recent periodic report is the quarterly report (10-Q) filed on October 29, 2026. It covers the period to September 30, 2026. Its newest filing of any kind is the planned insider sale from November 3, 2026.

When is INSMED Inc's next earnings report?

INSMED Inc's next report is expected around February 18, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

Similar companies

Compare INSM with

Compare INSM with any company

Follow INSM

Get an email when INSMED Inc files with the SEC: results, executive changes, material agreements and annual reports.

Free, no password. An email when INSM files with the SEC.

Where the numbers come from

Financial figures are the values INSMED Inc tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.