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NASDAQ · Health care

Edgewise Therapeutics, Inc. (EWTX)

In fiscal 2025 capital spending exceeded operating cash flow by $144.1M. At September 30, 2026 it held $68.7M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 4, 2026.

Free, no password. An email when EWTX files with the SEC.

Price
$48.74
+8.22% on the day · November 9, 2026
52-week range $16.98 to $48.78
Market cap
$5.3B

Key facts about Edgewise Therapeutics, Inc.

Net worth
Edgewise Therapeutics, Inc. has a market value (market cap) of $5.3B at the latest share price, and shareholders' equity of $1.6B on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Cash flow
In fiscal 2025 operations used $143.8M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 4, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Edgewise Therapeutics, Inc.'s next report is expected around February 25, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Edgewise Therapeutics, Inc. does

Edgewise Therapeutics, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker EWTX.

Revenue and profit by year

Net income
FY21: -$17.1M -$17.1M FY21FY21: -$42.8M -$42.8M FY21FY22: -$67.6M -$67.6M FY22FY23: -$100.2M -$100.2M FY23FY24: -$133.8M -$133.8M FY24FY25: -$167.8M -$167.8M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025n/a-$191.4M-$167.8M-$1.63-$144.1M
2024n/a-$158.8M-$133.8M-$1.45-$110.3M
2023n/a-$114.4M-$100.2M-$1.57-$97.7M
2022n/a-$71.7M-$67.6M-$1.26-$58.2M
2021n/a-$43.2M-$42.8M-$1.14-$34.2M
2021n/a-$17.2M-$17.1M-$23.17-$14.8M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around February 25, 2027.

Estimated from its filing rhythm: 52 weeks after its report of February 26, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Latest SEC filings

What Edgewise Therapeutics, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 5, 2026
  2. November 4, 2026
  3. November 4, 2026
    Quarterly report 10-Q · period to September 30, 2026Diluted EPS $9.65 versus -$0.39.
  4. August 14, 2026
  5. August 14, 2026
  6. August 14, 2026
  7. August 6, 2026
  8. August 6, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$0.53 versus -$0.34.
  9. August 6, 2026
  10. July 16, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 2, 2026. Insider transactions on SEC

Insider trades

What the people running Edgewise Therapeutics, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $126.7K worth of shares in the last 90 days and bought none on the open market. All of the selling was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$126.7K
last 90 days
Net sold
2,919
$126.7K
DateInsiderWhatSharesPriceValueFiling
October 1, 2026 Fox Jonathan CDirector Received as pay 308 - - Form 4
August 13, 2026 Donovan Joanne M.CMO Soldpre-planned (10b5-1) 2,919 $43.41 $126.7K Form 4
August 12, 2026 Koch KevinPresident and CEO, Director Exercised options 17,969 - - Form 4
August 12, 2026 Koch KevinPresident and CEO, Director Exercised options 21,875 - - Form 4
August 12, 2026 Koch KevinPresident and CEO, Director Sold 8,782 $43.64 $383.3K Form 4
August 12, 2026 Koch KevinPresident and CEO, Director Sold 8,276 $43.66 $361.3K Form 4
August 12, 2026 Koch KevinPresident and CEO, Director Sold 913 $44.33 $40.5K Form 4
August 12, 2026 Moore John RGeneral Counsel Exercised options 5,781 - - Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns EWTX

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Orbimed Advisors LLC13D, may seek influence with 3 related filers 14.5% 15,252,867 May 12, 2025
Paradigm BioCapital Advisors LP13G, passive with 3 related filers 9.5% 10,215,455 August 14, 2026
RA Capital Management, L.P.13G, passive with 3 related filers 7.8% 8,392,730 August 14, 2026
Janus Henderson Group PLC13G, passive 5.5% 5,915,556 May 15, 2026
Fmr LLC13G, passive with 1 related filers 5.1% 5,489,135 August 6, 2026

Latest filings below 5%: Baker Bros. Advisors LP 3.4% (August 14, 2026); Novo Holdings A/S 4.9% (April 27, 2026); Perceptive Advisors LLC 4.4% (August 14, 2025); Deerfield Management Company, L.P. 1.9% (November 14, 2024); EcoR1 Capital, LLC 1.3% (November 14, 2024).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 225 managers reported a position.

HolderSharesValueChange on quarter
Orbimed Advisors LLC15,518,492$630.5M0
Paradigm Biocapital Advisors LP10,215,455$415.1M+2,850,417
RA Capital Management, L.P.8,392,730$341M-2,035,707
BlackRock, Inc.6,606,336$268.4M+133,345
Jupiter Topco LLC6,075,331$246.9Mnew
Fmr LLC5,489,135$223M+4,472,083
Novo Holdings A/S5,350,000$217.4M0
Driehaus Capital Management LLC4,728,623$192.1M+250,681
Perceptive Advisors LLC4,373,974$177.7M-50,000
Vanguard Capital Management LLC3,860,670$156.9M+72,509
Baker Bros. Advisors LP3,701,719$150.4M-2,874,221
Siren, L.L.C.3,184,629$129.4M-1,245,634
Cormorant Asset Management, LP2,510,000$102M-750,000
Geode Capital Management, LLC2,174,051$88.3M+384,232
Integral Health Asset Management, LLC2,000,000$81.3M+400,000
Braidwell LP1,996,965$81.1M-350,618
Morgan Stanley1,948,597$79.2M-297,431
State Street Corp1,827,927$74.3M+111,104
Alliancebernstein L.P.2,119,024$66.7M+396,855
Mpm Bioimpact LLC1,620,780$65.9M-39,916

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

7 insiders reported holding 187,063 shares in total, about $9.1M at the last price.

HolderSharesAs of
Koch KevinPresident and CEO, Director 52,488 August 12, 2026
Derakhshan BehradChief Business Officer 31,826 August 12, 2026
Russell Alan JChief Scientific Officer, Director 31,466 August 12, 2026
Fox Jonathan CDirector 25,141 October 1, 2026
Edris BadreddinDirector 19,820 January 21, 2026
Moore John RGeneral Counsel 17,697 August 12, 2026
Donovan Joanne M.CMO 8,625 August 13, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about EWTX

What does Edgewise Therapeutics, Inc. do?

Edgewise Therapeutics, Inc. is a company in the Health care sector, listed on NASDAQ as EWTX. Its shares trade on NASDAQ under the ticker EWTX.

What is Edgewise Therapeutics, Inc.'s net worth?

Edgewise Therapeutics, Inc. has a market value (market cap) of $5.3B at the latest share price, and shareholders' equity of $1.6B on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Edgewise Therapeutics, Inc. profitable?

Yes. Over the twelve months to September 30, 2026 it reported net income of $1B.

When did Edgewise Therapeutics, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 4, 2026. It covers the period to September 30, 2026. Its newest filing of any kind is the passive stake changed from November 5, 2026.

When is Edgewise Therapeutics, Inc.'s next earnings report?

Edgewise Therapeutics, Inc.'s next report is expected around February 25, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Edgewise Therapeutics, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.