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Cytokinetics Inc (CYTK)

Cytokinetics Inc brought in $113.3M of revenue over the twelve months to September 30, 2026, up 29.9% from a year earlier. It posted a net loss of $777.9M. In fiscal 2025 capital spending exceeded operating cash flow by $534.8M. At September 30, 2026 it held $203.4M in cash against $418.7M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 4, 2026.

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Price
$57.00
+3.37% on the day · November 10, 2026
52-week range $53.55 to $88.31
Market cap
$7.9B
Revenue (last 12 months)
$113.3M
+29.9% year on year
Net margin
-686.6%

Key facts about Cytokinetics Inc

Net worth
Cytokinetics Inc has a market value (market cap) of $7.9B at the latest share price, and shareholders' equity of -$321.2M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $88M (+376.6% year on year), with a net loss of $785M. Over the 12 months to September 30, 2026: revenue $113.3M, net loss $777.9M.
Cash flow
In fiscal 2025 operations used $510M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 4, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Cytokinetics Inc's next report is expected around February 23, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Cytokinetics Inc does

Cytokinetics Inc is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker CYTK.

Revenue and profit by year

Revenue
FY18: $31.5M $31.5M FY18FY19: $26.9M $26.9M FY19FY20: $55.8M $55.8M FY20FY21: $70.4M $70.4M FY21FY22: $94.6M $94.6M FY22FY23: $7.5M $7.5M FY23FY24: $18.5M $18.5M FY24FY25: $88M $88M FY25
Net income
FY18: -$106.3M -$106.3M FY18FY19: -$121.7M -$121.7M FY19FY20: -$127.3M -$127.3M FY20FY21: -$215.3M -$215.3M FY21FY22: -$389M -$389M FY22FY23: -$526.2M -$526.2M FY23FY24: -$589.5M -$589.5M FY24FY25: -$785M -$785M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$88M-$612.3M-$785M-$6.54-$534.8M
2024$18.5M-$536.2M-$589.5M-$5.26-$399.8M
2023$7.5M-$496.2M-$526.2M-$5.45-$415.7M
2022$94.6M-$324.2M-$389M-$4.33-$310.9M
2021$70.4M-$186.3M-$215.3M-$2.80-$191.4M
2020$55.8M-$93.9M-$127.3M-$1.97-$2.1M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around February 23, 2027.

Estimated from its filing rhythm: 52 weeks after its report of February 24, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where CYTK ranks in Health care

Revenue$88M
#338 of 751 in Health care · Top 45%
Revenue growth+376.6%
#22 of 532 in Health care · Top 4%
Net margin-891.6%
#533 of 544 in Health care · Bottom 2%
Free cash flow margin-607.5%
#478 of 490 in Health care · Bottom 2%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Cytokinetics Inc has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 4, 2026
    Quarterly report 10-Q · period to September 30, 2026Revenue rose 2,356% to $47.6M versus the same quarter last year; diluted EPS -$1.37 versus -$2.55.
  2. November 4, 2026
  3. August 28, 2026
  4. August 13, 2026
  5. August 13, 2026
  6. August 6, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue fell 57% to $28.6M versus the same quarter last year; diluted EPS -$1.50 versus -$1.12.
  7. August 6, 2026
  8. July 8, 2026
  9. May 27, 2026
  10. May 27, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on November 9, 2026. Insider transactions on SEC

Insider trades

What the people running Cytokinetics Inc did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $11.9M worth of shares in the last 90 days and bought none on the open market. All of the selling was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$11.9M
last 90 days
Net sold
173,426
$11.9M
DateInsiderWhatSharesPriceValueFiling
November 3, 2026 Malik Fady IbrahamEVP Research & Development Exercised options 3,500 $7.80 $27.3K Form 4
November 3, 2026 Malik Fady IbrahamEVP Research & Development Soldpre-planned (10b5-1) 3,500 $62.93 $220.3K Form 4
November 2, 2026 Blum Robert IPresident & CEO, Director Exercised options 7,500 $10.60 $79.5K Form 4
November 2, 2026 Blum Robert IPresident & CEO, Director Soldpre-planned (10b5-1) 7,500 $62.81 $471.1K Form 4
October 20, 2026 Malik Fady IbrahamEVP Research & Development Exercised options 3,500 $7.80 $27.3K Form 4
October 20, 2026 Malik Fady IbrahamEVP Research & Development Soldpre-planned (10b5-1) 3,500 $64.01 $224K Form 4
October 16, 2026 Henderson John TDirector Received as pay 352 $63.92 $22.5K Form 4
October 16, 2026 Wierenga WendellDirector Received as pay 97 $63.92 $6.2K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns CYTK

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
T. Rowe Price Investment Management, Inc.13G, passive 14.5% 17,716,372 February 17, 2026
Vanguard Capital Management13G, passive 5.21% 6,422,042 April 29, 2026
Wellington Management Group LLP13G, passive with 2 related filers 5.1% 7,116,724 August 13, 2026

Latest filings below 5%: Fmr LLC 3.9% (July 8, 2026); The Vanguard Group 0% (March 26, 2026).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 482 managers reported a position.

HolderSharesValueChange on quarter
BlackRock, Inc.20,094,362$1.71B+3,546,351
Wellington Management Group Llp6,931,770$590.5M-1,077,719
Vanguard Portfolio Management LLC6,711,799$571.8M+868,017
State Street Corp6,494,233$553.2M+749,040
Vanguard Capital Management LLC6,117,515$521.2M+628,881
Fmr LLC5,031,782$428.7M-5,691,358
Avoro Capital Advisors LLC4,999,999$425.9M+1,666,666
Bank of America Corp4,635,709$394.9M+1,510,273
Geode Capital Management, LLC3,712,501$316.3M+497,086
Rtw Investments, LP2,862,003$243.8M+140,845
Polar Capital Holdings Plc2,253,649$192M+592,401
Goldman Sachs Group Inc1,761,588$150.1M-444,170
Capital Research Global Investors1,686,625$143.7M+915,626
Northern Trust Corp1,647,345$140.3M+205,711
Jpmorgan Chase & Co1,588,895$139.2M+685,090
William Blair Investment Management, LLC1,603,442$136.6M+515,851
Integral Health Asset Management, LLC1,600,000$136.3M0
Point72 Asset Management, L.P.1,587,712$135.3M+961,610
Charles Schwab Investment Management Inc1,565,781$133.4M+168,736
Susquehanna International Group, Llp1,549,458$132M+650,507

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

14 insiders reported holding 892,296 shares in total, about $50.9M at the last price.

HolderSharesAs of
Blum Robert IPresident & CEO, Director 278,544 November 2, 2026
Malik Fady IbrahamEVP Research & Development 153,902 November 3, 2026
Hessekiel JeffreyChief Legal & Admin Officer 107,943 March 15, 2026
Henderson John TDirector 78,712 October 16, 2026
Lee SungEVP, Chief Financial Officer 63,221 July 1, 2026
Callos AndrewEVP, Chief Commercial Officer 58,555 August 31, 2026
Wierenga WendellDirector 35,660 October 16, 2026
Wysenski NancyDirector 34,089 October 16, 2026
Bhanji MunaDirector 26,361 May 27, 2026
Harrington Robert ArthurDirector 22,127 October 16, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about CYTK

What does Cytokinetics Inc do?

Cytokinetics Inc is a company in the Health care sector, listed on NASDAQ as CYTK. Its shares trade on NASDAQ under the ticker CYTK.

What is Cytokinetics Inc's net worth?

Cytokinetics Inc has a market value (market cap) of $7.9B at the latest share price, and shareholders' equity of -$321.2M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Cytokinetics Inc profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $777.9M on revenue of $113.3M.

How much revenue does Cytokinetics Inc make?

Over the twelve months to September 30, 2026 Cytokinetics Inc reported revenue of $113.3M. That is 29.9% more than a year earlier.

When did Cytokinetics Inc last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 4, 2026. It covers the period to September 30, 2026. Its newest filing of any kind is the planned insider sale from November 9, 2026.

When is Cytokinetics Inc's next earnings report?

Cytokinetics Inc's next report is expected around February 23, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Cytokinetics Inc tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.