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NASDAQ · Health care

Clene Inc. (CLNN)

Clene Inc. brought in $197K of revenue over the twelve months to June 30, 2026, down 31.1% from a year earlier. It posted a net loss of $39.5M. In fiscal 2025 capital spending exceeded operating cash flow by $18.6M. At June 30, 2026 it held $9.7M in cash against $17.6M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 14, 2026.

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Price
$4.38
+10.89% on the day · November 9, 2026
52-week range $3.02 to $10.84
Market cap
$56.3M
Revenue (last 12 months)
$197K
-31.1% year on year
Net margin
-20,059.9%

Key facts about Clene Inc.

Net worth
Clene Inc. has a market value (market cap) of $56.3M at the latest share price, and shareholders' equity of -$24.8M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $200K (-41.5% year on year), with a net loss of $26.2M. Over the 12 months to June 30, 2026: revenue $197K, net loss $39.5M.
Cash flow
In fiscal 2025 operations used $18.5M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on August 14, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR
Next earnings report
Clene Inc.'s next report was expected around October 13, 2026 and is not on file with the SEC yet.

What Clene Inc. does

Clene Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker CLNN.

Revenue and profit by year

Revenue
FY20: $206K $206K FY20FY21: $723K $723K FY21FY22: $473K $473K FY22FY23: $654K $654K FY23FY24: $342K $342K FY24FY25: $200K $200K FY25
Net income
FY20: -$16.2M -$16.2M FY20FY20: -$19.3M -$19.3M FY20FY21: -$9.7M -$9.7M FY21FY22: -$29.9M -$29.9M FY22FY23: -$49.5M -$49.5M FY23FY24: -$39.4M -$39.4M FY24FY25: -$26.2M -$26.2M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$200K-$23.1M-$26.2M-$2.65-$18.6M
2024$342K-$33.1M-$39.4M-$5.67-$21.3M
2023$654K-$40.5M-$49.5M-$9.43-$30.5M
2022$473K-$48.4M-$29.9M-$9.23-$44.2M
2021$723K-$50M-$9.7M-$3.21-$36M
2020$206K-$20.2M-$19.3M-$22.07-$19.3M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

A report was expected around October 13, 2026 and is not on file yet.

Estimated from its filing rhythm: 52 weeks after its report of October 14, 2025. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where CLNN ranks in Health care

Revenue$200K
#704 of 751 in Health care · Bottom 6%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Clene Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. September 16, 2026
  2. August 14, 2026
  3. August 14, 2026
  4. August 14, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue rose 233% to $90K versus the same quarter last year; diluted EPS -$1.08 versus -$0.78.
  5. August 11, 2026
  6. August 10, 2026
  7. August 4, 2026
  8. June 5, 2026
  9. May 22, 2026
  10. May 22, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on September 18, 2026. Insider transactions on SEC

Insider trades

What the people running Clene Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider bought or sold shares on the open market in the last 90 days. The 3 reported changes were pay in shares, option exercises, shares withheld for tax or gifts.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days
DateInsiderWhatSharesPriceValueFiling
September 16, 2026 Mosca AlisonDirector, 10% owner Received as payindirect 198,171 $3.28 $650K Form 4
September 16, 2026 Etherington Robert DeePresident & CEO, Director Received as pay 15,244 $3.28 $50K Form 4
September 16, 2026 Matlin David JDirector Received as pay 434,451 $3.28 $1.4M Form 4
May 12, 2026 Ugwumba Chidozie10% owner Soldindirect 73,296 $6.20 $454.4K Form 4
May 11, 2026 Ugwumba Chidozie10% owner Soldindirect 22,177 $6.75 $149.7K Form 4
May 4, 2026 Ugwumba Chidozie10% owner Soldindirect 72,884 $6.80 $495.6K Form 4
May 1, 2026 Ugwumba Chidozie10% owner Soldindirect 5,795 $6.01 $34.8K Form 4
April 30, 2026 Ugwumba Chidozie10% owner Soldindirect 5,736 $6.08 $34.9K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns CLNN

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Alison Mosca13G, passive 13% 1,831,990 May 14, 2026
Vivo Opportunity Fund Holdings, L.P.13G, passive with 3 related filers 9.99% 1,321,675 August 14, 2026
Empery Asset Management, LP13G, passive with 1 related filers 7.17% 916,532 August 4, 2026
David Lisonbee13G, passive with 1 related filers 6.5% 555,328 February 14, 2025

Latest filings below 5%: Ugwumba Chidozie 0% (August 11, 2026); AWM Investment Company, Inc. 4.7% (November 13, 2025); Armistice Capital, LLC 4.99% (February 14, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 33 managers reported a position.

HolderSharesValueChange on quarter
Empery Asset Management, LP916,532$5.6Mnew
Scoggin Management LP600,000$3.7M+300,000
Boxer Capital Management, LLC477,515$2.9M0
Ensign Peak Advisors, Inc348,062$2.1M+90,190
Vanguard Capital Management LLC333,706$2.1M+25,476
Geode Capital Management, LLC102,215$629.6K+6,341
BlackRock, Inc.61,559$378.9K+27,760
Vanguard Fiduciary Trust Co57,765$355.5K+14,050
Lunt Capital Management, Inc.52,260$321.7K0
Parsons Capital Management Inc37,243$229.2K0
PEAK6 LLC30,012$184.7K-20,000
State Street Corp29,801$183.4K0
Morgan Stanley19,858$122.2K+26
Northern Trust Corp19,723$121.4K+3,580
ADAR1 Capital Management, LLC15,000$92.3Knew
Arax Advisory Partners11,140$68.6K+10,570
Penn Davis McFarland Inc11,000$67.7K0
Jane Street Group, LLC10,203$62.8Knew
Wells Fargo & Company5,927$36.5K0
Vanguard Global Advisers, LLC5,609$34.5K0

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

4 insiders reported holding 1,830,256 shares in total, about $8M at the last price.

HolderSharesAs of
Matlin David JDirector 912,275 September 16, 2026
Mosca AlisonDirector, 10% owner 759,171759,171 held indirectly September 16, 2026
Ugwumba Chidozie10% owner 103,417103,417 held indirectly May 12, 2026
Etherington Robert DeePresident & CEO, Director 55,393 September 16, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about CLNN

What does Clene Inc. do?

Clene Inc. is a company in the Health care sector, listed on NASDAQ as CLNN. Its shares trade on NASDAQ under the ticker CLNN.

What is Clene Inc.'s net worth?

Clene Inc. has a market value (market cap) of $56.3M at the latest share price, and shareholders' equity of -$24.8M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Clene Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $39.5M on revenue of $197K.

How much revenue does Clene Inc. make?

Over the twelve months to June 30, 2026 Clene Inc. reported revenue of $197K. That is 31.1% less than a year earlier.

When did Clene Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 14, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the insider trade from September 18, 2026.

When is Clene Inc.'s next earnings report?

Clene Inc.'s next report was expected around October 13, 2026 and is not on file with the SEC yet.

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Where the numbers come from

Financial figures are the values Clene Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.