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C4 Therapeutics, Inc. (CCCC)

C4 Therapeutics, Inc. brought in $32.3M of revenue over the twelve months to September 30, 2026, up 7.2% from a year earlier. It posted a net loss of $91.1M. In fiscal 2025 capital spending exceeded operating cash flow by $99.3M. At September 30, 2026 it held $32.4M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 5, 2026.

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Price
$3.14
-0.48% on the day · November 10, 2026
52-week range $1.69 to $5.17
Market cap
$385.7M
Revenue (last 12 months)
$32.3M
+7.2% year on year
Net margin
-282.2%

Key facts about C4 Therapeutics, Inc.

Net worth
C4 Therapeutics, Inc. has a market value (market cap) of $385.7M at the latest share price, and shareholders' equity of $228.2M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $35.9M (+1.0% year on year), with a net loss of $105M. Over the 12 months to September 30, 2026: revenue $32.3M, net loss $91.1M.
Cash flow
In fiscal 2025 operations used $98.7M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 5, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
C4 Therapeutics, Inc.'s next report is expected around February 25, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What C4 Therapeutics, Inc. does

C4 Therapeutics, Inc. is registered with the SEC under industry code SIC 2836 (Biological Products, (No Diagnostic Substances)). Its shares trade on NASDAQ under the ticker CCCC.

Revenue and profit by year

Revenue
FY21: $45.8M $45.8M FY21FY22: $31.1M $31.1M FY22FY23: $20.8M $20.8M FY23FY24: $35.6M $35.6M FY24FY25: $35.9M $35.9M FY25
Net income
FY20: -$34.1M -$34.1M FY20FY20: -$66.3M -$66.3M FY20FY21: -$83.9M -$83.9M FY21FY22: -$128.2M -$128.2M FY22FY23: -$132.5M -$132.5M FY23FY24: -$105.3M -$105.3M FY24FY25: -$105M -$105M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$35.9M-$115.2M-$105M-$1.27-$99.3M
2024$35.6M-$119.6M-$105.3M-$1.52-$65.3M
2023$20.8M-$139M-$132.5M-$2.67-$108.5M
2022$31.1M-$129.5M-$128.2M-$2.62-$111.4M
2021$45.8M-$82.1M-$83.9M-$1.82-$88.2M
2020n/a-$60.4M-$66.3M-$5.83-$67.9M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around February 25, 2027.

Estimated from its filing rhythm: 52 weeks after its report of February 26, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where CCCC ranks in Health care

Revenue$35.9M
#429 of 751 in Health care · Bottom 43%
Revenue growth+1.0%
#394 of 532 in Health care · Bottom 26%
Net margin-292.1%
#495 of 544 in Health care · Bottom 9%
Free cash flow margin-276.2%
#449 of 490 in Health care · Bottom 8%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What C4 Therapeutics, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 5, 2026
    Quarterly report 10-Q · period to September 30, 2026Revenue fell 25% to $8.5M versus the same quarter last year; diluted EPS -$0.16 versus -$0.44.
  2. November 5, 2026
  3. September 25, 2026
  4. August 14, 2026
  5. August 14, 2026
  6. August 14, 2026
  7. August 12, 2026
  8. August 11, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue rose 2.8% to $6.6M versus the same quarter last year; diluted EPS -$0.18 versus -$0.37.
  9. August 11, 2026
  10. July 27, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 2, 2026. Insider transactions on SEC

Insider trades

What the people running C4 Therapeutics, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider bought or sold shares on the open market in the last 90 days. The 4 reported changes were pay in shares, option exercises, shares withheld for tax or gifts.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days
DateInsiderWhatSharesPriceValueFiling
October 1, 2026 Grogan Donna RoyDirector Received as pay 4,618 $3.14 $14.5K Form 4
October 1, 2026 Anderson Kenneth CarlDirector Received as pay 3,662 $3.14 $11.5K Form 4
September 18, 2026 Adams KendraChief Financial Officer Exercised options 6,250 - - Form 4
September 18, 2026 Adams KendraChief Financial Officer Shares withheld for tax 2,775 $3.39 $9.4K Form 4
July 10, 2026 Reyno LeonardChief Medical Officer Exercised options 15,325 - - Form 4
July 10, 2026 Reyno LeonardChief Medical Officer Shares withheld for tax 7,397 $4.06 $30K Form 4
July 1, 2026 Anderson Kenneth CarlDirector Received as pay 2,650 $4.34 $11.5K Form 4
July 1, 2026 Grogan Donna RoyDirector Received as pay 3,341 $4.34 $14.5K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns CCCC

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Lynx1 Capital Management LP13G, passive with 1 related filers 9.99% 15,423,691 August 14, 2026
Soleus Capital Master Fund, L.P.13G, passive with 8 related filers 9.99% 10,361,860 February 12, 2026
RA Capital Management, L.P.13G, passive with 3 related filers 9.9% 11,383,696 August 14, 2026
Sirenia Capital Management LP13G, passive with 1 related filers 9.9% 23,505,000 May 15, 2026
Squadron Master Fund LP13G, passive with 3 related filers 6.9% 7,600,000 August 14, 2026
BCLS II Equity Opportunities, LP13G, passive with 2 related filers 6.25% 6,060,000 October 24, 2025

Latest filings below 5%: Point72 Asset Management, L.P. 0.2% (May 15, 2026); Wasatch Advisors LP 4.7% (April 22, 2026); OrbiMed Capital LLC 1% (February 17, 2026); Commodore Capital LP 4.8% (November 14, 2024); T. Rowe Price Associates, Inc. 0.6% (November 14, 2024).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 148 managers reported a position.

HolderSharesValueChange on quarter
Morgan Stanley8,867,338$41.4M-205,062
RA Capital Management, L.P.8,000,000$37.4M0
BlackRock, Inc.7,896,718$36.9M+5,848,192
Lynx1 Capital Management LP7,326,691$34.2M+327,789
Squadron Capital Management LLC7,200,000$33.6M+4,950,000
Bain Capital Life Sciences Investors, LLC7,171,910$33.5M0
Jpmorgan Chase & Co4,747,424$20.7M+1,524,370
Vanguard Capital Management LLC4,417,731$20.6M+555,879
Citadel Advisors LLC4,187,580$19.6M+1,676,565
Goldman Sachs Group Inc3,530,991$16.5M+1,143,613
Wasatch Advisors LP3,522,644$16.5M+560,883
Two Sigma Investments, LP3,469,707$16.2M+434,073
Soleus Capital Management, L.P.3,377,981$15.8M-425,961
Silverarc Capital Management, LLC3,032,060$14.2M+1,120,275
Bank of America Corp2,656,359$12.4M+297,118
Geode Capital Management, LLC2,522,163$11.8M+1,571,120
Ikarian Capital, LLC2,433,000$11.4Mnew
State Street Corp2,115,621$9.9M+1,732,648
Candriam S.C.A.1,796,937$8.4Mnew
D. E. Shaw & Co., Inc.1,740,989$8.1M+680,658

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

9 insiders reported holding 2,992,254 shares in total, about $9.4M at the last price.

HolderSharesAs of
Hirsch AndrewPresident & CEO, Director 1,074,934 February 15, 2026
Adams KendraChief Financial Officer 382,323 September 18, 2026
Reyno LeonardChief Medical Officer 372,406 July 10, 2026
Mahaney PaigeChief Scientific Officer 336,910 February 14, 2026
Schick KellyChief People Officer 299,881 February 14, 2026
Boyle Scott NChief Business Officer 298,801 February 14, 2026
Grogan Donna RoyDirector 79,471 October 1, 2026
Anderson Kenneth CarlDirector 75,612 October 1, 2026
Mossler MarkChief Accounting Officer 71,916 February 14, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about CCCC

What does C4 Therapeutics, Inc. do?

C4 Therapeutics, Inc. is a company in the Health care sector, listed on NASDAQ as CCCC. Its shares trade on NASDAQ under the ticker CCCC.

What is C4 Therapeutics, Inc.'s net worth?

C4 Therapeutics, Inc. has a market value (market cap) of $385.7M at the latest share price, and shareholders' equity of $228.2M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is C4 Therapeutics, Inc. profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $91.1M on revenue of $32.3M.

How much revenue does C4 Therapeutics, Inc. make?

Over the twelve months to September 30, 2026 C4 Therapeutics, Inc. reported revenue of $32.3M. That is 7.2% more than a year earlier.

When did C4 Therapeutics, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 5, 2026. It covers the period to September 30, 2026.

When is C4 Therapeutics, Inc.'s next earnings report?

C4 Therapeutics, Inc.'s next report is expected around February 25, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values C4 Therapeutics, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.