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Biocryst Pharmaceuticals Inc (BCRX)

Biocryst Pharmaceuticals Inc brought in $961.5M of revenue over the twelve months to September 30, 2026, up 60.3% from a year earlier. It posted a net loss of $359.7M. Operating cash flow minus capital spending left $344.9M of free cash flow in fiscal 2025. At September 30, 2026 it held $97M in cash against $395.6M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 4, 2026.

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Price
$7.63
-0.78% on the day · November 9, 2026
52-week range $6.23 to $11.22
Market cap
$1.9B
Revenue (last 12 months)
$961.5M
+60.3% year on year
Net margin
-37.4%
P/E
6.3
on FY2025 diluted EPS

Key facts about Biocryst Pharmaceuticals Inc

Net worth
Biocryst Pharmaceuticals Inc has a market value (market cap) of $1.9B at the latest share price, and shareholders' equity of -$397.4M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $874.8M (+94.1% year on year), with net income of $263.9M. Over the 12 months to September 30, 2026: revenue $961.5M, net loss $359.7M.
Cash flow
In fiscal 2025 operations brought in $347.4M of cash; after $2.5M of capital spending, free cash flow was $344.9M.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 4, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Biocryst Pharmaceuticals Inc's next report is expected around January 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Biocryst Pharmaceuticals Inc does

Biocryst Pharmaceuticals Inc is registered with the SEC under industry code SIC 2836 (Biological Products, (No Diagnostic Substances)). Its shares trade on NASDAQ under the ticker BCRX.

Revenue and profit by year

Revenue
FY18: $20.7M $20.7M FY18FY19: $48.8M $48.8M FY19FY20: $17.8M $17.8M FY20FY21: $157.2M $157.2M FY21FY22: $270.8M $270.8M FY22FY23: $331.4M $331.4M FY23FY24: $450.7M $450.7M FY24FY25: $874.8M $874.8M FY25
Net income
FY18: -$101.3M -$101.3M FY18FY19: -$108.9M -$108.9M FY19FY20: -$182.8M -$182.8M FY20FY21: -$184.1M -$184.1M FY21FY22: -$247.1M -$247.1M FY22FY23: -$226.5M -$226.5M FY23FY24: -$88.9M -$88.9M FY24FY25: $263.9M $263.9M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$874.8M$341M$263.9M$1.21$344.9M
2024$450.7M-$2.5M-$88.9M-$0.43-$53.1M
2023$331.4M-$103.7M-$226.5M-$1.18-$97.3M
2022$270.8M-$148.4M-$247.1M-$1.33-$163.2M
2021$157.2M-$177.7M-$184.1M-$1.03-$144.5M
2020$17.8M-$174.8M-$182.8M-$1.09-$135.6M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around January 11, 2027.

Estimated from its filing rhythm: 52 weeks after its report of January 12, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where BCRX ranks in Health care

Revenue$874.8M
#162 of 751 in Health care · Top 21%
Revenue growth+94.1%
#58 of 532 in Health care · Top 11%
Net margin30.2%
#33 of 544 in Health care · Top 6%
Free cash flow margin39.4%
#15 of 490 in Health care · Top 3%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Biocryst Pharmaceuticals Inc has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 4, 2026
    Quarterly report 10-Q · period to September 30, 2026Revenue rose 13% to $180.3M versus the same quarter last year; diluted EPS $0.14 versus $0.06.
  2. November 4, 2026
  3. August 14, 2026
  4. August 7, 2026
  5. August 5, 2026
  6. August 5, 2026
    Quarterly report 10-Q · period to June 30, 2026Revenue rose 34% to $218.3M versus the same quarter last year; diluted EPS $0.30 versus $0.02.
  7. August 5, 2026
  8. August 4, 2026
  9. June 29, 2026
  10. June 12, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on September 2, 2026. Insider transactions on SEC

What is BCRX worth? A DCF from its reported cash flow

Insider trades

What the people running Biocryst Pharmaceuticals Inc did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider bought or sold shares on the open market in the last 90 days. The 5 reported changes were pay in shares, option exercises, shares withheld for tax or gifts.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days
DateInsiderWhatSharesPriceValueFiling
August 31, 2026 Frank StevenDirector Received as pay 1,288 $9.70 $12.5K Form 4
August 31, 2026 McKee Amy EDirector Received as pay 644 $9.70 $6.2K Form 4
August 31, 2026 Milano VincentDirector Received as pay 1,159 $9.70 $11.2K Form 4
August 31, 2026 Milne Jill C.Director Received as pay 1,288 $9.70 $12.5K Form 4
August 31, 2026 Stonehouse Jon PDirector Received as pay 644 $9.70 $6.2K Form 4
June 11, 2026 Heggie TheresaDirector Received as pay 15,294 - - Form 4
June 11, 2026 McKee Amy EDirector Received as pay 15,294 - - Form 4
June 11, 2026 Stonehouse Jon PDirector Received as pay 15,294 - - Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns BCRX

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Deerfield Mgmt, L.P.13G, passive with 3 related filers 6.81% 14,341,000 February 12, 2026
RA Capital Management, L.P.13G, passive with 3 related filers 6.2% 15,827,186 August 14, 2026
Vanguard Capital Management13G, passive 5.16% 12,961,172 April 29, 2026

Latest filings below 5%: The Vanguard Group 0% (March 26, 2026); Avoro Capital Advisors LLC 4.2% (May 15, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 318 managers reported a position.

HolderSharesValueChange on quarter
BlackRock, Inc.23,893,036$238.9M+1,242,048
RA Capital Management, L.P.15,827,186$158.3M0
State Street Corp15,191,098$151.9M+2,982,738
Deerfield Management Company, L.P.15,096,403$151M+58,403
Vanguard Capital Management LLC11,364,236$113.6M+228,474
Vanguard Portfolio Management LLC11,139,158$111.4M-105,467
TCG Crossover Management, LLC11,020,968$110.2M0
Perceptive Advisors LLC10,308,888$103.1M+2,874,855
Jupiter Topco LLC9,540,764$95.3Mnew
Vestal Point Capital, LP8,300,000$83M+1,275,000
Two Sigma Investments, LP6,775,349$67.8M+382,721
Geode Capital Management, LLC6,248,046$62.5M+465,270
Aberdeen Group plc5,310,871$53.1M+270,201
UBS Group AG5,078,280$50.8M+134,286
Bank of America Corp4,801,284$48M-290,481
Goldman Sachs Group Inc4,481,874$44.8M+2,134,431
Frazier Life Sciences Management, L.P.4,009,240$40.1M0
Nuveen, LLC4,007,237$40.1M+187,974
Nantahala Capital Management, LLC3,802,320$38M+1,814,923
Millennium Management LLC3,394,729$33.9M+3,207,008

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

13 insiders reported holding 3,668,932 shares in total, about $28M at the last price.

HolderSharesAs of
Stonehouse Jon PChief Executive Officer, Director 1,380,41940,000 held indirectly August 31, 2026
Gayer Charles KPresident and CCO 952,583 December 22, 2025
Barnes Alane PChief Legal Officer 400,703 May 13, 2026
Ghias BabarChief Financial Officer 268,700 December 17, 2025
Menon SandeepChief R&D Officer 205,150 April 6, 2026
Milano VincentDirector 109,642 August 31, 2026
Heggie TheresaDirector 80,646 June 11, 2026
Levin Alan GDirector 79,565 June 11, 2026
McKee Amy EDirector 47,821 August 31, 2026
Sanders MachelleDirector 45,936 June 11, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about BCRX

What does Biocryst Pharmaceuticals Inc do?

Biocryst Pharmaceuticals Inc is a company in the Health care sector, listed on NASDAQ as BCRX. Its shares trade on NASDAQ under the ticker BCRX.

What is Biocryst Pharmaceuticals Inc's net worth?

Biocryst Pharmaceuticals Inc has a market value (market cap) of $1.9B at the latest share price, and shareholders' equity of -$397.4M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Biocryst Pharmaceuticals Inc profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $359.7M on revenue of $961.5M.

How much revenue does Biocryst Pharmaceuticals Inc make?

Over the twelve months to September 30, 2026 Biocryst Pharmaceuticals Inc reported revenue of $961.5M. That is 60.3% more than a year earlier.

When did Biocryst Pharmaceuticals Inc last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 4, 2026. It covers the period to September 30, 2026.

When is Biocryst Pharmaceuticals Inc's next earnings report?

Biocryst Pharmaceuticals Inc's next report is expected around January 11, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Biocryst Pharmaceuticals Inc tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.