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NASDAQ · Health care

Aytu Biopharma, Inc (AYTU)

Aytu Biopharma, Inc reported revenue of $57.6M in fiscal 2026, down 13.3% from a year earlier. It posted a net loss of $14.3M. Operating cash flow minus capital spending left $3.3M of free cash flow in fiscal 2026. At June 30, 2026 it held $26.3M in cash against $11M of debt. Its latest periodic report to the SEC is the annual report (10-K) filed on September 22, 2026.

Watch AYTU in 60 seconds
Price
$2.28
-1.30% on the day · September 25, 2026
52-week range $1.65 to $3.07
Market cap
$24.5M
Revenue (FY2026)
$57.6M
-13.3% year on year
Net margin
-24.8%

What Aytu Biopharma, Inc does

Aytu Biopharma, Inc is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker AYTU.

Revenue and profit by year

Revenue
FY20: $7.3M $7.3M FY20FY20: $27.6M $27.6M FY20FY21: $65.6M $65.6M FY21FY22: $96.7M $96.7M FY22FY23: $107.4M $107.4M FY23FY24: $65.2M $65.2M FY24FY25: $66.4M $66.4M FY25FY26: $57.6M $57.6M FY26
Net income
FY20: -$27.1M -$27.1M FY20FY20: -$13.6M -$13.6M FY20FY21: -$58.3M -$58.3M FY21FY22: -$108.8M -$108.8M FY22FY23: -$17.1M -$17.1M FY23FY24: -$15.8M -$15.8M FY24FY25: -$13.6M -$13.6M FY25FY26: -$14.3M -$14.3M FY26

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2026$57.6M-$8.3M-$14.3M-$1.16$3.3M
2025$66.4M-$7.8M-$13.6M-$2.16-$2.2M
2024$65.2M-$1.6M-$15.8M-$2.86-$1.7M
2023$107.4M-$17.1M-$17.1M-$5.11n/a
2022$96.7M-$109.9M-$108.8M-$74.01-$28.8M
2021$65.6M-$58.9M-$58.3M-$68.68-$28.3M

Full financial statements: income, balance sheet and cash flow

Next report expected around November 12, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 13, 2025. Not a date the company has announced. See the report calendar

Where AYTU ranks in Health care

Revenue$57.6M
#362 of 646 in Health care · Bottom 44%
Revenue growth-13.3%
#424 of 474 in Health care · Bottom 11%
Net margin-24.8%
#300 of 485 in Health care · Bottom 38%
Free cash flow margin5.6%
#157 of 440 in Health care · Top 36%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Aytu Biopharma, Inc has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. September 22, 2026
    Annual report 10-K · period to June 30, 2026Revenue fell 13% to $57.6M versus the prior year; diluted EPS -$1.16 versus -$2.16.
  2. September 22, 2026
  3. August 14, 2026
  4. June 25, 2026
  5. May 13, 2026
    Quarterly report 10-Q · period to March 31, 2026Revenue fell 33% to $12.4M versus the same quarter last year; diluted EPS -$0.53 versus $0.21.
  6. May 13, 2026
  7. April 2, 2026
  8. February 17, 2026
  9. February 13, 2026
  10. February 3, 2026
    Quarterly report 10-Q · period to December 31, 2025Revenue fell 6.5% to $15.2M versus the same quarter last year; diluted EPS -$1.05 versus -$0.26.

Recent insider filings (Forms 3, 4 and 144): 10, the latest on July 30, 2026. Insider transactions on SEC

What is AYTU worth? A DCF from its reported cash flow

Insider trades

What the people running Aytu Biopharma, Inc did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider bought or sold shares on the open market in the last 90 days. The 8 reported changes were pay in shares, option exercises, shares withheld for tax or gifts.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days
DateInsiderWhatSharesPriceValueFiling
July 28, 2026 Donofrio John Jr.Director Received as pay 10,000 - - Form 4
July 28, 2026 Dockery CarlDirector Received as pay 10,000 - - Form 4
July 28, 2026 Jain AbhinavDirector Received as pay 10,000 - - Form 4
July 28, 2026 Liu Vivian HDirector Received as pay 10,000 - - Form 4
July 28, 2026 Selhorn Ryan JChief Financial Officer Received as pay 25,000 - - Form 4
July 28, 2026 Disbrow JarrettChief Business Officer Received as pay 15,000 - - Form 4
July 28, 2026 Pyszczymuka GregChief Commercial Officer Received as pay 20,000 - - Form 4
July 28, 2026 Disbrow Joshua R.Chief Executive Officer, Director Received as pay 30,000 - - Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns AYTU

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Nantahala Capital Management, LLC13D, may seek influence with 2 related filers 14.4% 1,086,812 June 9, 2025
Stonepine Capital Management, LLC13G, passive with 3 related filers 9.9% 906,063 August 13, 2025
AWM Investment Company, Inc.13G, passive 5.8% 619,574 February 13, 2026

Latest filings below 5%: Lytton Laurence W 4.99% (August 14, 2026); Philotimo Fund, LP 0% (November 12, 2025).

Largest institutional holders

No Form 13F positions imported for this company yet.

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

8 insiders reported holding 558,855 shares in total, about $1.3M at the last price.

HolderSharesAs of
Disbrow Joshua R.Chief Executive Officer, Director 237,203 July 28, 2026
Disbrow JarrettChief Business Officer 76,568 July 28, 2026
Selhorn Ryan JChief Financial Officer 74,743 July 28, 2026
Pyszczymuka GregChief Commercial Officer 56,102 July 28, 2026
Dockery CarlDirector 31,152 July 28, 2026
Liu Vivian HDirector 29,825 July 28, 2026
Jain AbhinavDirector 29,500 July 28, 2026
Donofrio John Jr.Director 23,762 July 28, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about AYTU

What does Aytu Biopharma, Inc do?

Aytu Biopharma, Inc is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker AYTU.

Is Aytu Biopharma, Inc profitable?

No. In fiscal 2026 it reported a net loss of $14.3M on revenue of $57.6M.

How much revenue does Aytu Biopharma, Inc make?

In fiscal 2026 Aytu Biopharma, Inc reported revenue of $57.6M. That is 13.3% less than a year earlier.

When did Aytu Biopharma, Inc last report?

Its most recent periodic report is the annual report (10-K) filed on September 22, 2026. It covers the period to June 30, 2026.

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Where the numbers come from

Financial figures are the values Aytu Biopharma, Inc tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.