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Axsome Therapeutics, Inc. (AXSM)

Axsome Therapeutics, Inc. brought in $776.6M of revenue over the twelve months to June 30, 2026, up 56.9% from a year earlier. It posted a net loss of $191.6M. In fiscal 2025 capital spending exceeded operating cash flow by $93.9M. At June 30, 2026 it held $319.9M in cash against $188M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 10, 2026.

Price
$195.09
-0.48% on the day · September 25, 2026
52-week range $116.18 to $260.19
Market cap
$10.2B
Revenue (last 12 months)
$776.6M
+56.9% year on year
Net margin
-24.7%

What Axsome Therapeutics, Inc. does

Axsome Therapeutics, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker AXSM.

Revenue and profit by year

Revenue
FY22: $50M $50M FY22FY23: $270.6M $270.6M FY23FY24: $385.7M $385.7M FY24FY25: $638.5M $638.5M FY25
Net income
FY18: -$31M -$31M FY18FY19: -$68.3M -$68.3M FY19FY20: -$102.9M -$102.9M FY20FY21: -$130.4M -$130.4M FY21FY22: -$187.1M -$187.1M FY22FY23: -$239.2M -$239.2M FY23FY24: -$287.2M -$287.2M FY24FY25: -$183.2M -$183.2M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$638.5M-$166.8M-$183.2M-$3.68-$93.9M
2024$385.7M-$280.6M-$287.2M-$5.99-$128.7M
2023$270.6M-$231.8M-$239.2M-$5.27-$145.7M
2022$50M-$179.8M-$187.1M-$4.60-$117.2M
2021n/a-$124.7M-$130.4M-$3.47-$108.5M
2020n/a-$99.1M-$102.9M-$2.77-$78.5M
Next report expected around November 2, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 3, 2025. Not a date the company has announced. See the report calendar

Where AXSM ranks in Health care

Revenue$638.5M
#177 of 523 in Health care · Top 34%
Revenue growth+65.5%
#59 of 437 in Health care · Top 13%
Net margin-28.7%
#286 of 447 in Health care · Bottom 36%
Free cash flow margin-14.7%
#262 of 408 in Health care · Bottom 36%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Axsome Therapeutics, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. August 10, 2026
    Quarterly report 10-Q · period to June 30, 2026
  2. August 10, 2026
  3. July 27, 2026
  4. July 15, 2026
  5. June 9, 2026
  6. June 9, 2026
  7. June 3, 2026
  8. May 4, 2026
    Quarterly report 10-Q · period to March 31, 2026
  9. May 4, 2026
  10. April 30, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on September 3, 2026. Insider transactions on SEC

Insider trades

What the people running Axsome Therapeutics, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $2.1M worth of shares in the last 90 days and bought none on the open market. All of the selling was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$2.1M
last 90 days
Net sold
10,000
$2.1M
DateInsiderWhatSharesPriceValueFiling
September 3, 2026 Jacobson Mark L.Chief Operating Officer Exercised options 10,000 $12.95 $129.5K Form 4
September 3, 2026 Jacobson Mark L.Chief Operating Officer Soldpre-planned (10b5-1) 10,000 $208.65 $2.1M Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

All filings on SEC EDGAR

Questions about AXSM

What does Axsome Therapeutics, Inc. do?

Axsome Therapeutics, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker AXSM.

Is Axsome Therapeutics, Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $191.6M on revenue of $776.6M.

How much revenue does Axsome Therapeutics, Inc. make?

Over the twelve months to June 30, 2026 Axsome Therapeutics, Inc. reported revenue of $776.6M. That is 56.9% more than a year earlier.

When did Axsome Therapeutics, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 10, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the insider trade from September 3, 2026.

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Where the numbers come from

Financial figures are the values Axsome Therapeutics, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.