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NASDAQ · Health care

aTYR PHARMA INC (ATYR)

It posted a net loss of $60.8M. In fiscal 2025 capital spending exceeded operating cash flow by $62.1M. At June 30, 2026 it held $16.2M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 7, 2026.

Free, no password. An email when ATYR files with the SEC.

Price
$7.56
-0.26% on the day · November 10, 2026
52-week range $4.08 to $44.40
Market cap
$741.5M

Key facts about aTYR PHARMA INC

Net worth
aTYR PHARMA INC has a market value (market cap) of $741.5M at the latest share price, and shareholders' equity of $48.8M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $190K (-19.1% year on year), with a net loss of $74.1M.
Cash flow
In fiscal 2025 operations used $62M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on August 7, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR
Next earnings report
aTYR PHARMA INC's next report was expected around November 5, 2026 and is not on file with the SEC yet.

What aTYR PHARMA INC does

aTYR PHARMA INC is registered with the SEC under industry code SIC 2836 (Biological Products, (No Diagnostic Substances)). Its shares trade on NASDAQ under the ticker ATYR.

Revenue and profit by year

Revenue
FY19: $422K $422K FY19FY20: $10.5M $10.5M FY20FY21: $0 $0 FY21FY22: $10.4M $10.4M FY22FY23: $353K $353K FY23FY24: $235K $235K FY24FY25: $190K $190K FY25
Net income
FY18: -$34.5M -$34.5M FY18FY19: -$16.2M -$16.2M FY19FY20: -$16.2M -$16.2M FY20FY21: -$33.8M -$33.8M FY21FY22: -$45.3M -$45.3M FY22FY23: -$50.4M -$50.4M FY23FY24: -$64M -$64M FY24FY25: -$74.1M -$74.1M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$190K-$77.6M-$74.1M-$0.80-$62.1M
2024$235K-$67.9M-$64M-$0.86-$69.2M
2023$353K-$54.9M-$50.4M-$0.94-$37.4M
2022$10.4M-$46.4M-$45.3M-$1.60-$43.5M
2021$0-$34M-$33.8M-$1.77-$33.3M
2020$10.5M-$15.9M-$16.2M-$1.77-$15.5M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

A report was expected around November 5, 2026 and is not on file yet.

Estimated from its filing rhythm: 52 weeks after its report of November 6, 2025. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Where ATYR ranks in Health care

Revenue$190K
#705 of 751 in Health care · Bottom 6%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What aTYR PHARMA INC has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. September 24, 2026
  2. September 11, 2026
  3. August 31, 2026
  4. August 7, 2026
  5. August 7, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$0.11 versus -$0.22.
  6. August 7, 2026
  7. August 6, 2026
  8. July 31, 2026
  9. July 27, 2026
  10. June 8, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 1, 2026. Insider transactions on SEC

Insider trades

What the people running aTYR PHARMA INC did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider trades were reported in the last 90 days.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days
DateInsiderWhatSharesPriceValueFiling
May 27, 2026 Schimmel PaulDirector Boughtindirect 100,000 $0.50 $49.6K Form 4
February 4, 2026 Denyes NancyGeneral Counsel Sold 1,118 $0.98 $1.1K Form 4
February 4, 2026 Broadfoot Jill MarieChief Financial Officer Sold 1,558 $0.98 $1.5K Form 4
February 4, 2026 Shukla SanjayPresident and CEO, Director Sold 3,745 $0.98 $3.7K Form 4
February 3, 2026 Denyes NancyGeneral Counsel Exercised options 2,687 - - Form 4
February 3, 2026 Broadfoot Jill MarieChief Financial Officer Exercised options 3,750 - - Form 4
February 3, 2026 Shukla SanjayPresident and CEO, Director Exercised options 10,375 - - Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns ATYR

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

No holder of 5% or more has filed about this company in that window.

Latest filings below 5%: Fmr LLC 2.5% (August 6, 2026); The Vanguard Group 0% (March 26, 2026); Point72 Asset Management, L.P. 3.2% (May 15, 2025); Logos Global Management LP 2.1% (November 14, 2024).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 90 managers reported a position.

HolderSharesValueChange on quarter
Federated Hermes, Inc.8,509,678$5.1M-2,000,000
Vanguard Capital Management LLC3,808,091$2.3M-4,041
Kalehua Capital Management LLC3,576,334$2.1Mnew
Aqr Capital Management LLC2,610,548$1.6M+2,114,530
Fmr LLC2,471,418$1.5M-12,235,425
BlackRock, Inc.1,827,332$1.1M-4,616,572
Jane Street Group, LLC1,721,297$1M+1,672,795
UBS Group AG1,531,151$914.1K-2,336,062
Morgan Stanley1,343,636$801.9K+118,169
Two Sigma Investments, LP1,245,147$743.1K+100,582
Citadel Advisors LLC1,242,067$741.3K+1,194,695
Geode Capital Management, LLC1,177,020$702.7K-1,208,465
Susquehanna International Group, Llp747,039$445.8K-119,705
Millennium Management LLC656,051$391.5K-985,195
Goldman Sachs Group Inc641,208$382.7K+357,972
Vanguard Fiduciary Trust Co576,125$343.9K-75,707
State Street Corp494,951$295.4K-1,259,448
Marshall Wace, Llp368,120$220.9K+230,002
XTX Topco Ltd226,678$135.3K+115,255
Northern Trust Corp220,141$131.4K-490,964

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

4 insiders reported holding 1,003,116 shares in total, about $7.6M at the last price.

HolderSharesAs of
Schimmel PaulDirector 779,143779,143 held indirectly May 27, 2026
Shukla SanjayPresident and CEO, Director 153,553 February 4, 2026
Broadfoot Jill MarieChief Financial Officer 37,296 February 4, 2026
Denyes NancyGeneral Counsel 33,124 February 4, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about ATYR

What does aTYR PHARMA INC do?

aTYR PHARMA INC is a company in the Health care sector, listed on NASDAQ as ATYR. Its shares trade on NASDAQ under the ticker ATYR.

What is aTYR PHARMA INC's net worth?

aTYR PHARMA INC has a market value (market cap) of $741.5M at the latest share price, and shareholders' equity of $48.8M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is aTYR PHARMA INC profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $60.8M.

When did aTYR PHARMA INC last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 7, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the insider trade from October 1, 2026.

When is aTYR PHARMA INC's next earnings report?

aTYR PHARMA INC's next report was expected around November 5, 2026 and is not on file with the SEC yet.

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Where the numbers come from

Financial figures are the values aTYR PHARMA INC tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.