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NASDAQ · Health care

Aprea Therapeutics, Inc. (APRE)

It posted a net loss of $12.3M. At June 30, 2026 it held $41.2M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 12, 2026.

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Price
$0.45
+0.27% on the day · November 11, 2026
52-week range $0.41 to $1.49
Market cap
$5.6M

Key facts about Aprea Therapeutics, Inc.

Net worth
Aprea Therapeutics, Inc. has a market value (market cap) of $5.6M at the latest share price, and shareholders' equity of $38.5M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Cash flow
In fiscal 2025 operations used $12.9M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on August 12, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR
Next earnings report
Aprea Therapeutics, Inc.'s next report was expected around November 11, 2026 and is not on file with the SEC yet.

What Aprea Therapeutics, Inc. does

Aprea Therapeutics, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker APRE.

Revenue and profit by year

Net income
FY19: -$15.5M -$15.5M FY19FY19: -$28.1M -$28.1M FY19FY20: -$53.5M -$53.5M FY20FY21: -$37.1M -$37.1M FY21FY22: -$112.7M -$112.7M FY22FY23: -$14.3M -$14.3M FY23FY24: -$13M -$13M FY24FY25: -$12.6M -$12.6M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025n/a-$13.2M-$12.6M-$1.93n/a
2024n/a-$14.3M-$13M-$2.35-$13.6M
2023n/a-$15.5M-$14.3M-$3.79-$12.3M
2022n/a-$113.4M-$112.7M-$65.21n/a
2021n/a-$37.4M-$37.1M-$33.46n/a
2020n/an/a-$53.5M-$48.54-$41.8M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

A report was expected around November 11, 2026 and is not on file yet.

Estimated from its filing rhythm: 52 weeks after its report of November 12, 2025. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Latest SEC filings

What Aprea Therapeutics, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. August 28, 2026
  2. August 13, 2026
  3. August 12, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$0.07 versus -$0.53.
  4. August 12, 2026
  5. July 23, 2026
  6. June 17, 2026
  7. May 15, 2026
  8. May 13, 2026
    Quarterly report 10-Q · period to March 31, 2026Diluted EPS -$0.22 versus -$0.66.
  9. May 13, 2026
  10. April 30, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on June 17, 2026. Insider transactions on SEC

Insider trades

What the people running Aprea Therapeutics, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider trades were reported in the last 90 days.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days
DateInsiderWhatSharesPriceValueFiling
June 16, 2026 Seizinger Bernd R.Director Received as pay 3,135 - - Form 4
June 16, 2026 Pamukcu RifatDirector Received as pay 3,135 - - Form 4
June 16, 2026 Duey MarcDirector Received as pay 3,135 - - Form 4
June 16, 2026 Bizzari Jean-PierreDirector Received as pay 3,135 - - Form 4
June 16, 2026 Henneman John B IIIDirector Received as pay 3,135 - - Form 4
June 16, 2026 Peters RichardDirector Received as pay 3,135 - - Form 4
June 16, 2026 Gruia GabrielaDirector Received as pay 3,135 - - Form 4
June 16, 2026 Grissinger MichaelDirector Received as pay 3,135 - - Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns APRE

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Soleus Private Equity Fund III, L.P.13G, passive with 8 related filers 9.99% 1,271,080 April 1, 2026
Orin Hirschman13G, passive with 1 related filers 9.9% 1,186,294 April 27, 2026
Squadron Master Fund LP13G, passive with 3 related filers 9.9% 1,271,081 April 7, 2026
Vestal Point Capital, LP13G, passive with 1 related filers 9.9% 22,654,832 May 15, 2026

Latest filings below 5%: Lytton Laurence W 3.2% (August 13, 2026); Nantahala Capital Management, LLC 4.5% (February 13, 2026); Sio Capital Management, LLC 1.93% (November 12, 2025); Stonepine Capital Management, LLC 4.3% (May 14, 2025).

Largest institutional holders

No Form 13F positions imported for this company yet.

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

10 insiders reported holding 788,206 shares in total, about $352.2K at the last price.

HolderSharesAs of
Gilad OrenPresident/CEO, Director 393,895 March 12, 2026
Duey MarcDirector 259,290 June 16, 2026
Seizinger Bernd R.Director 48,910 June 16, 2026
Hamill John P.SrVP/CFO/Prin Fin & Acct Ofcr 43,528 March 12, 2026
Henneman John B IIIDirector 13,364 June 16, 2026
Pamukcu RifatDirector 8,581 June 16, 2026
Peters RichardDirector 6,254 June 16, 2026
Grissinger MichaelDirector 6,024 June 16, 2026
Gruia GabrielaDirector 4,180 June 16, 2026
Bizzari Jean-PierreDirector 4,180 June 16, 2026

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about APRE

What does Aprea Therapeutics, Inc. do?

Aprea Therapeutics, Inc. is a company in the Health care sector, listed on NASDAQ as APRE. Its shares trade on NASDAQ under the ticker APRE.

What is Aprea Therapeutics, Inc.'s net worth?

Aprea Therapeutics, Inc. has a market value (market cap) of $5.6M at the latest share price, and shareholders' equity of $38.5M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Aprea Therapeutics, Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $12.3M.

When did Aprea Therapeutics, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 12, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the other event from August 28, 2026.

When is Aprea Therapeutics, Inc.'s next earnings report?

Aprea Therapeutics, Inc.'s next report was expected around November 11, 2026 and is not on file with the SEC yet.

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Where the numbers come from

Financial figures are the values Aprea Therapeutics, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.