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NYSE · Health care

Annovis Bio, Inc. (ANVS)

It posted a net loss of $49.5M. At June 30, 2026 it held $18.7M in cash. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on August 14, 2026.

Free, no password. An email when ANVS files with the SEC.

Price
$0.85
-6.18% on the day · November 10, 2026
52-week range $0.62 to $5.50
Market cap
$36M

Key facts about Annovis Bio, Inc.

Net worth
Annovis Bio, Inc. has a market value (market cap) of $36M at the latest share price, and shareholders' equity of -$4.3M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $0, with a net loss of $28.9M.
Cash flow
In fiscal 2025 operations used $25.6M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on August 14, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR
Next earnings report
Annovis Bio, Inc.'s next report is expected around November 12, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

What Annovis Bio, Inc. does

Annovis Bio, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NYSE under the ticker ANVS.

Revenue and profit by year

Revenue
FY20: $0 $0 FY20FY21: $0 $0 FY21FY22: $0 $0 FY22FY23: $0 $0 FY23FY24: $0 $0 FY24FY25: $0 $0 FY25
Net income
FY20: -$991K -$991K FY20FY20: -$5.5M -$5.5M FY20FY21: -$14.5M -$14.5M FY21FY22: -$25.3M -$25.3M FY22FY23: -$56.2M -$56.2M FY23FY24: -$24.6M -$24.6M FY24FY25: -$28.9M -$28.9M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$0-$29.7M-$28.9M-$1.40n/a
2024$0-$26.7M-$24.6M-$2.31n/a
2023$0-$45M-$56.2M-$6.23n/a
2022$0-$25.5M-$25.3M-$3.10n/a
2021$0-$14.5M-$14.5M-$1.90n/a
2020$0-$6.6M-$5.5M-$0.87n/a

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around November 12, 2026.

Estimated from its filing rhythm: 52 weeks after its report of November 13, 2025. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Latest SEC filings

What Annovis Bio, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. September 11, 2026
  2. August 25, 2026
  3. August 14, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$0.40 versus -$0.32.
  4. August 14, 2026
  5. August 14, 2026
  6. July 29, 2026
  7. July 10, 2026
  8. June 17, 2026
  9. May 20, 2026
  10. May 15, 2026
    Quarterly report 10-Q · period to March 31, 2026Diluted EPS -$0.63 versus -$0.32.

Recent insider filings (Forms 3, 4 and 144): 10, the latest on May 21, 2026. Insider transactions on SEC

Insider trades

What the people running Annovis Bio, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

No insider trades were reported in the last 90 days.

Bought (open market)
$0
last 90 days
Sold
$0
last 90 days
DateInsiderWhatSharesPriceValueFiling
May 20, 2026 Hoffman Michael BDirector Bought 2,562 $1.75 $4.5K Form 4
May 20, 2026 Hoffman Michael BDirector Bought 18,849 $1.80 $33.9K Form 4
May 20, 2026 Hoffman Michael BDirector Bought 54,933 $1.90 $104.4K Form 4
April 2, 2026 Hoffman Michael BDirector Bought 713,800 $2.10 $1.5M Form 4
December 8, 2025 Hoffman Michael BDirector Bought 30,000 $4.34 $130.2K Form 4
December 8, 2025 Hoffman Michael BDirector Bought 15,000 $4.24 $63.6K Form 4
November 24, 2025 Hoffman Michael BDirector Bought 1,489 $4.13 $6.1K Form 4
November 24, 2025 Hoffman Michael BDirector Bought 9,200 $3.85 $35.4K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns ANVS

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Highbridge Capital Management, LLC13G, passive 6.1% 2,775,578 August 14, 2026
Empery Asset Management, LP13G, passive with 1 related filers 5.64% 2,401,476 July 29, 2026

Latest filings below 5%: CVI Investments, Inc. 4.9% (May 12, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 61 managers reported a position.

HolderSharesValueChange on quarter
Empery Asset Management, LP2,401,476$4.5Mnew
Marshall Wace, Llp1,842,339$3.4M+654,840
Vanguard Capital Management LLC1,647,322$3.1M+774,941
Tudor Investment Corp ET AL1,357,134$2.5Mnew
Renaissance Technologies LLC1,002,200$1.9M+654,600
Two Sigma Investments, LP579,571$1.1M-48,088
Geode Capital Management, LLC283,817$528.1K+36,304
BlackRock, Inc.249,856$464.7K+110,323
Citadel Advisors LLC243,682$453.2Knew
Vanguard Fiduciary Trust Co177,530$330.2K+45,488
Susquehanna International Group, Llp146,804$273.1K-71,532
Quadrature Capital Ltd90,884$169Knew
State Street Corp77,735$144.6K0
Northern Trust Corp68,070$126.6K-73,660
First National Trust Co60,000$111.6K+20,000
Sherry Group, Inc.57,270$106.5K0
Headlands Technologies LLC48,071$89.4Knew
Wescott Financial Advisory Group, LLC41,607$77.4K0
Bridgeway Capital Management, LLC37,677$70.1K0
Wells Fargo & Company30,307$56.4K+16,000

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

3 insiders reported holding 4,590,612 shares in total, about $3.9M at the last price.

HolderSharesAs of
Hoffman Michael BDirector 3,364,883 May 20, 2026
Maccecchini Maria-LuisaPresident & CEO, Director 1,212,020 October 28, 2025
Bruck ClaudineDirector 13,709 September 10, 2025

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about ANVS

What does Annovis Bio, Inc. do?

Annovis Bio, Inc. is a company in the Health care sector, listed on NYSE as ANVS. Its shares trade on NYSE under the ticker ANVS.

What is Annovis Bio, Inc.'s net worth?

Annovis Bio, Inc. has a market value (market cap) of $36M at the latest share price, and shareholders' equity of -$4.3M on its balance sheet at June 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Annovis Bio, Inc. profitable?

No. Over the twelve months to June 30, 2026 it reported a net loss of $49.5M.

When did Annovis Bio, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on August 14, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the proxy statement from September 11, 2026.

When is Annovis Bio, Inc.'s next earnings report?

Annovis Bio, Inc.'s next report is expected around November 12, 2026. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Annovis Bio, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.