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NASDAQ · Health care

Annexon, Inc. (ANNX)

It posted a net loss of $199M. In fiscal 2025 capital spending exceeded operating cash flow by $186.5M. At September 30, 2026 it held $102.4M in cash against $49.3M of debt. Its latest periodic report to the SEC is the quarterly report (10-Q) filed on November 9, 2026.

Free, no password. An email when ANNX files with the SEC.

Price
$4.23
+0.71% on the day · November 9, 2026
52-week range $2.54 to $7.18
Market cap
$801.9M

Key facts about Annexon, Inc.

Net worth
Annexon, Inc. has a market value (market cap) of $801.9M at the latest share price, and shareholders' equity of $142.8M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Cash flow
In fiscal 2025 operations used $186.4M of cash.
Latest report
The latest periodic report (quarterly report, 10-Q) was filed with the SEC on November 9, 2026 and covers the period to September 30, 2026. Open on SEC EDGAR
Next earnings report
Annexon, Inc.'s next report is expected around March 29, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

What Annexon, Inc. does

Annexon, Inc. is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker ANNX.

Revenue and profit by year

Net income
FY20: -$37.2M -$37.2M FY20FY20: -$63.4M -$63.4M FY20FY21: -$130.3M -$130.3M FY21FY22: -$141.9M -$141.9M FY22FY23: -$134.2M -$134.2M FY23FY24: -$138.2M -$138.2M FY24FY25: -$206.7M -$206.7M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025n/a-$216.4M-$206.7M-$1.34-$186.5M
2024n/a-$154.1M-$138.2M-$1.01-$118M
2023n/a-$143.7M-$134.2M-$1.77-$121.3M
2022n/a-$145.6M-$141.9M-$2.60-$122.8M
2021n/a-$130.7M-$130.3M-$3.40-$107.8M
2020n/a-$63.5M-$63.4M-$4.15-$53.6M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Next report expected around March 29, 2027.

Estimated from its filing rhythm: 52 weeks after its report of March 30, 2026. Not a date the company has announced. See the report calendar · Earnings, quarter by quarter

Latest SEC filings

What Annexon, Inc. has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. November 9, 2026
    Quarterly report 10-Q · period to September 30, 2026Diluted EPS -$0.25 versus -$0.37.
  2. November 9, 2026
  3. November 5, 2026
  4. August 12, 2026
    Quarterly report 10-Q · period to June 30, 2026Diluted EPS -$0.28 versus -$0.34.
  5. August 12, 2026
  6. August 10, 2026
  7. August 7, 2026
  8. August 6, 2026
  9. July 30, 2026
  10. July 27, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on September 25, 2026. Insider transactions on SEC

Insider trades

What the people running Annexon, Inc. did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders bought $99.8K worth of shares on the open market in the last 90 days and sold none.

Bought (open market)
$99.8K
last 90 days
Sold
$0
last 90 days
Net bought
26,065
$99.8K
DateInsiderWhatSharesPriceValueFiling
September 24, 2026 Love DouglasPRESIDENT AND CEO, Director Bought 26,065 $3.83 $99.8K Form 4
June 11, 2026 Yednock TedEVP & CHIEF INNOVATION OFFICER Exercised options 30,646 $1.85 $56.7K Form 4
May 28, 2026 Satter Muneer ADirector Boughtindirect 613,497 $5.41 $3.3M Form 4
May 11, 2026 Carson William H.Director Bought 8,000 $5.78 $46.2K Form 4
April 10, 2026 Carson William H.Director Bought 8,000 $6.20 $49.6K Form 4
March 10, 2026 Carson William H.Director Bought 8,000 $5.67 $45.4K Form 4
March 2, 2026 Lew JenniferEVP & CHIEF FINANCIAL OFFICER Sold 5,565 $5.42 $30.2K Form 4
March 2, 2026 Dananberg JamieCHIEF MEDICAL OFFICER Sold 5,820 $5.43 $31.6K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns ANNX

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
Fmr LLC13G, passive with 1 related filers 11.9% 19,518,496 July 8, 2026
Redmile Group, LLC13G, passive with 2 related filers 9.9% 17,918,459 July 8, 2026
Satter Muneer A13D, may seek influence 7.2% 10,444,134 November 21, 2025
Bvf Partners L P13G, passive with 9 related filers 5.4% 8,698,173 May 15, 2026

Latest filings below 5%: The Vanguard Group 0% (March 26, 2026); Logos Global Management LP 0% (August 14, 2025); Point72 Asset Management, L.P. 0.1% (May 15, 2025); BCLS I Investco, LP 4.9% (February 14, 2025); BB Biotech AG 4.9% (November 14, 2024).

Largest institutional holders

No Form 13F positions imported for this company yet.

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

9 insiders reported holding 11,685,822 shares in total, about $49.4M at the last price.

HolderSharesAs of
Satter Muneer ADirector 10,342,13410,342,134 held indirectly May 28, 2026
Love DouglasPRESIDENT AND CEO, Director 390,476 September 24, 2026
Yednock TedEVP & CHIEF INNOVATION OFFICER 184,807 June 11, 2026
Overdorf MichaelEVP & CHIEF BUSINESS OFFICER 182,625 March 2, 2026
Artis Dean RichardEVP & CHIEF SCIENTIFIC OFFICER 180,093 March 2, 2026
Lew JenniferEVP & CHIEF FINANCIAL OFFICER 170,700 March 2, 2026
Dananberg JamieCHIEF MEDICAL OFFICER 123,582 March 2, 2026
Carson William H.Director 78,405 May 11, 2026
Choi JungDirector 33,00033,000 held indirectly December 1, 2025

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about ANNX

What does Annexon, Inc. do?

Annexon, Inc. is a company in the Health care sector, listed on NASDAQ as ANNX. Its shares trade on NASDAQ under the ticker ANNX.

What is Annexon, Inc.'s net worth?

Annexon, Inc. has a market value (market cap) of $801.9M at the latest share price, and shareholders' equity of $142.8M on its balance sheet at September 30, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Annexon, Inc. profitable?

No. Over the twelve months to September 30, 2026 it reported a net loss of $199M.

When did Annexon, Inc. last report?

Its most recent periodic report is the quarterly report (10-Q) filed on November 9, 2026. It covers the period to September 30, 2026.

When is Annexon, Inc.'s next earnings report?

Annexon, Inc.'s next report is expected around March 29, 2027. That is an estimate from its filing rhythm, not a date the company has announced.

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Where the numbers come from

Financial figures are the values Annexon, Inc. tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.