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NASDAQ · Health care

Anaptysbio, Inc (ANAB)

Anaptysbio, Inc brought in $232.4M of revenue over the twelve months to March 31, 2026, up 107.7% from a year earlier. It posted a net loss of $26.8M. Operating cash flow minus capital spending left $19.6M of free cash flow in fiscal 2025. At March 31, 2026 it held $248.5M in cash. Its latest periodic report to the SEC is the transition-period annual report (10-KT) filed on September 21, 2026.

Free, no password. An email when ANAB files with the SEC.

Price
$47.97
+3.27% on the day · November 9, 2026
52-week range $21.47 to $72.36
Market cap
$1.4B
Revenue (last 12 months)
$232.4M
+107.7% year on year
Net margin
-11.5%

Key facts about Anaptysbio, Inc

Net worth
Anaptysbio, Inc has a market value (market cap) of $1.4B at the latest share price, and shareholders' equity of $12.7M on its balance sheet at March 31, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.
Revenue and profit
In fiscal 2025 revenue was $234.6M (+157.0% year on year), with a net loss of $13.2M. Over the 12 months to March 31, 2026: revenue $232.4M, net loss $26.8M.
Cash flow
In fiscal 2025 operations brought in $19.7M of cash; after $87K of capital spending, free cash flow was $19.6M.
Latest report
The latest periodic report (transition-period annual report, 10-KT) was filed with the SEC on September 21, 2026 and covers the period to June 30, 2026. Open on SEC EDGAR

What Anaptysbio, Inc does

Anaptysbio, Inc is registered with the SEC under industry code SIC 2834 (Pharmaceutical Preparations). Its shares trade on NASDAQ under the ticker ANAB.

Revenue and profit by year

Revenue
FY18: $5M $5M FY18FY19: $8M $8M FY19FY20: $75M $75M FY20FY21: $63.2M $63.2M FY21FY22: $10.3M $10.3M FY22FY23: $17.2M $17.2M FY23FY24: $91.3M $91.3M FY24FY25: $234.6M $234.6M FY25
Net income
FY18: -$61.7M -$61.7M FY18FY19: -$97.3M -$97.3M FY19FY20: -$19.9M -$19.9M FY20FY21: -$57.8M -$57.8M FY21FY22: -$128.7M -$128.7M FY22FY23: -$163.6M -$163.6M FY23FY24: -$145.2M -$145.2M FY24FY25: -$13.2M -$13.2M FY25

Fiscal years as reported in annual reports. Amounts in USD.

Key figures

Fiscal yearRevenueOperating incomeNet incomeDiluted EPSFree cash flow
2025$234.6M$226.9M-$13.2M-$0.44$19.6M
2024$91.3M$66.2M-$145.2M-$4.92-$135.7M
2023$17.2M-$164.4M-$163.6M-$6.08-$121.6M
2022$10.3M-$115.2M-$128.7M-$4.57-$74M
2021$63.2M-$56.8M-$57.8M-$2.11-$47.3M
2020$75M-$23.9M-$19.9M-$0.73-$14.7M

Earnings: every quarter and the next report date

Full financial statements: income, balance sheet and cash flow

Where ANAB ranks in Health care

Revenue$234.6M
#261 of 751 in Health care · Top 35%
Revenue growth+157.0%
#38 of 532 in Health care · Top 7%
Net margin-5.6%
#255 of 544 in Health care · Top 47%
Free cash flow margin8.4%
#147 of 490 in Health care · Top 30%

Latest fiscal year of every company in the sector with the figure reported. Revenue is ranked among companies reporting in US dollars; growth and margins among companies with at least 10 million of revenue. Health care

Latest SEC filings

What Anaptysbio, Inc has filed recently, newest first. Each links to the original document on SEC EDGAR.

  1. September 21, 2026
    Transition-period annual report 10-KT · period to June 30, 2026
  2. September 21, 2026
  3. August 14, 2026
  4. August 11, 2026
  5. July 30, 2026
  6. June 29, 2026
  7. June 29, 2026
  8. June 29, 2026
  9. June 22, 2026
  10. May 29, 2026

Recent insider filings (Forms 3, 4 and 144): 10, the latest on October 2, 2026. Insider transactions on SEC

What is ANAB worth? A DCF from its reported cash flow

Insider trades

What the people running Anaptysbio, Inc did with its shares, from the Form 4 filings they must send the SEC within two business days.

Insiders sold $249.4K worth of shares in the last 90 days and bought none on the open market. All of the selling was pre-planned under Rule 10b5-1 trading plans.

Bought (open market)
$0
last 90 days
Sold
$249.4K
last 90 days
Net sold
5,000
$249.4K
DateInsiderWhatSharesPriceValueFiling
October 1, 2026 Renton HollingsDirector Exercised options 5,000 $18.03 $90.2K Form 4
October 1, 2026 Renton HollingsDirector Soldpre-planned (10b5-1) 5,000 $49.87 $249.4K Form 4
September 15, 2026 Orwin John ADirector Exercised options 1,300 - - Form 4
June 15, 2026 Renton HollingsDirector Exercised options 6,030 - - Form 4
June 15, 2026 Orwin John ADirector Exercised options 6,030 - - Form 4
June 15, 2026 Schmid John P.Director Exercised options 6,030 - - Form 4
March 30, 2026 Schmid John P.Director Sold 12,596 $55.71 $701.7K Form 4
March 30, 2026 Schmid John P.Director Sold 7,527 $56.70 $426.8K Form 4

All insider filings on SEC.gov · Where insiders are buying across the market

Who owns ANAB

Three views from three kinds of SEC filings, each with its own date. They overlap and are not added up.

5% holders

Anyone who owns more than 5% of a class of shares must say so on Schedule 13D (if they may seek to influence the company) or 13G (a passive holder). The latest filing of each holder is shown: 13G filings of the last 2 years, 13D of the last 3.

HolderOf classSharesFiled
EcoR1 Capital, LLC13D, may seek influence with 2 related filers 25.8% 7,794,996 August 16, 2024
Sirenia Capital Management LP13G, passive with 1 related filers 5% 1,491,959 August 14, 2026

Latest filings below 5%: Point72 Asset Management, L.P. 0.2% (May 15, 2026); The Vanguard Group 0% (March 26, 2026); Millennium Management LLC 2.9% (January 16, 2026); Mathew P. Arens 3.12% (November 14, 2025); Fmr LLC 0.9% (June 6, 2025).

Largest institutional holders

Positions that investment managers reported on Form 13F for the quarter ended June 30, 2026, largest first, with the change on the quarter ended March 31, 2026. Managers file 13F up to 45 days after a quarter ends. 213 managers reported a position.

HolderSharesValueChange on quarter
EcoR1 Capital, LLC7,880,094$531.9M0
BlackRock, Inc.1,844,049$124.5M+162,669
Tang Capital Management LLC1,330,879$89.8M0
State Street Corp1,286,194$86.8M+293,749
Vanguard Capital Management LLC906,233$61.2M+53,082
Affinity Asset Advisors, LLC826,109$55.8M-113,891
Sanofi821,917$55.5M0
Millennium Management LLC807,316$54.5M+331,744
Woodline Partners LP717,014$48.4M+372,758
683 Capital Management, LLC660,000$44.6M+35,000
Geode Capital Management, LLC637,873$43.1M+117,632
Palo Alto Investors LP603,489$40.7M-34,672
Goldman Sachs Group Inc584,070$39.4M+251,327
First Light Asset Management, LLC582,004$39.3M+16,573
D. E. Shaw & Co., Inc.539,666$36.4M-39,630
Vanguard Portfolio Management LLC527,858$35.6M+7,988
Apis Capital Advisors, LLC497,000$33.5M+259,000
Sofinnova Investments, Inc.493,536$33.3M+245,283
Arrowstreet Capital, Limited Partnership488,651$33M-3,469
Nuveen, LLC420,664$28.4M+104,599

Insiders

Reported holdings of insiders who filed a Form 4 in the last 12 months: the shares each one held after their latest reported transaction. This is not the total held by all insiders.

9 insiders reported holding 658,942 shares in total, about $31.6M at the last price.

HolderSharesAs of
Faga DanielPresident, CEO, Director 495,965 March 27, 2026
Lizzul Paul F.Chief Medical Officer 42,088 January 8, 2026
Schmid John P.Director 37,652 June 15, 2026
Mulroy DennisCHIEF FINANCIAL OFFICER 21,852 January 8, 2026
Orwin John ADirector 17,995 September 15, 2026
Loumeau Eric JCHIEF LEGAL OFFICER 12,835 February 11, 2026
Renton HollingsDirector 10,995 October 1, 2026
Marquet MagdaDirector 9,930 January 15, 2026
Ware J. AnthonyDirector 9,630 December 23, 2025

Schedule 13D/13G filings on SEC.gov

All filings on SEC EDGAR

Questions about ANAB

What does Anaptysbio, Inc do?

Anaptysbio, Inc is a company in the Health care sector, listed on NASDAQ as ANAB. Its shares trade on NASDAQ under the ticker ANAB.

What is Anaptysbio, Inc's net worth?

Anaptysbio, Inc has a market value (market cap) of $1.4B at the latest share price, and shareholders' equity of $12.7M on its balance sheet at March 31, 2026. A company's "net worth" usually means one of these: what the market pays for all its shares, or its assets minus its liabilities.

Is Anaptysbio, Inc profitable?

No. Over the twelve months to March 31, 2026 it reported a net loss of $26.8M on revenue of $232.4M.

How much revenue does Anaptysbio, Inc make?

Over the twelve months to March 31, 2026 Anaptysbio, Inc reported revenue of $232.4M. That is 107.7% more than a year earlier.

When did Anaptysbio, Inc last report?

Its most recent periodic report is the transition-period annual report (10-KT) filed on September 21, 2026. It covers the period to June 30, 2026. Its newest filing of any kind is the insider trade from October 2, 2026.

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Where the numbers come from

Financial figures are the values Anaptysbio, Inc tagged in its own SEC filings (XBRL), taken from the latest filing for each period, so restatements replace older figures. Revenue, profit and cash flow are for full fiscal years unless marked as the last twelve months, which is the sum of the four most recent quarters. Where a company reports only the full year, the fourth quarter is the year minus the first three.

Prices are delayed end-of-day market data in the listing currency, and market cap moves with the price. P/E is shown only when earnings per share are positive. Nothing here is investment advice.